Clinical impression that fibroids is a major risk factor for preterm birth needs reconsideration

Key clinical point: Uterine fibroids did not increase the risk for preterm births and were not associated with any clinical preterm birth subtype.

Major finding: Prevalence of fibroids was similar in pregnancies ending in preterm and term births (10.2% and 10.3%, respectively). Presence of fibroids was not associated with an overall risk for preterm birth (adjusted risk ratio [aRR], 0.88; 95% confidence interval [CI], 0.62-1.24) or preterm birth subtypes like medically indicated (aRR, 0.92; 95% CI, 0.43-1.96) or spontaneous (aRR, 1.27; 95% CI, 0.76-2.11) preterm births.

Study details: Findings are from a prospective cohort including 4,622 women with singleton pregnancies resulting in a live birth after 20 weeks of gestation.

Disclosures: This study was funded by National Institutes of Health, American Water Works Association Research Foundation, and the National Institute of General Medical Studies. The authors declared no conflict of interests.

Source: Sundermann AC et al. BMC Pregnancy Childbirth. 2021 Aug 17. doi: 10.1186/s12884-021-03968-2.

Key clinical point: Uterine fibroids did not increase the risk for preterm births and were not associated with any clinical preterm birth subtype.

Major finding: Prevalence of fibroids was similar in pregnancies ending in preterm and term births (10.2% and 10.3%, respectively). Presence of fibroids was not associated with an overall risk for preterm birth (adjusted risk ratio [aRR], 0.88; 95% confidence interval [CI], 0.62-1.24) or preterm birth subtypes like medically indicated (aRR, 0.92; 95% CI, 0.43-1.96) or spontaneous (aRR, 1.27; 95% CI, 0.76-2.11) preterm births.

Study details: Findings are from a prospective cohort including 4,622 women with singleton pregnancies resulting in a live birth after 20 weeks of gestation.

Disclosures: This study was funded by National Institutes of Health, American Water Works Association Research Foundation, and the National Institute of General Medical Studies. The authors declared no conflict of interests.

Source: Sundermann AC et al. BMC Pregnancy Childbirth. 2021 Aug 17. doi: 10.1186/s12884-021-03968-2.

Key clinical point: Uterine fibroids did not increase the risk for preterm births and were not associated with any clinical preterm birth subtype.

Major finding: Prevalence of fibroids was similar in pregnancies ending in preterm and term births (10.2% and 10.3%, respectively). Presence of fibroids was not associated with an overall risk for preterm birth (adjusted risk ratio [aRR], 0.88; 95% confidence interval [CI], 0.62-1.24) or preterm birth subtypes like medically indicated (aRR, 0.92; 95% CI, 0.43-1.96) or spontaneous (aRR, 1.27; 95% CI, 0.76-2.11) preterm births.

Study details: Findings are from a prospective cohort including 4,622 women with singleton pregnancies resulting in a live birth after 20 weeks of gestation.

Disclosures: This study was funded by National Institutes of Health, American Water Works Association Research Foundation, and the National Institute of General Medical Studies. The authors declared no conflict of interests.

Source: Sundermann AC et al. BMC Pregnancy Childbirth. 2021 Aug 17. doi: 10.1186/s12884-021-03968-2.