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Disaster response and global health

Corona virus and disaster preparedness campaign

On January 28, 2020, the US Centers for Disease Control and Prevention (CDC) issued a travel advisory recommending against all nonessential travel to China, in light of the 2019 novel coronavirus (2019-nCoV) outbreak.

Shortly thereafter, a plane that flew out of China was directed to land on a US air force base in California on Friday, January 31. Since then, other US government flights have evacuated patients to military bases throughout the country. The CDC issued a federal quarantine order lasting the 14-day incubation period to these repatriated US citizens. Nearby hospitals were debriefed and command centers set up in anticipation of any required intervention.

Dr. John Agapian
Dr. John Agapian


Initial diagnostic testing for 2019-nCoV could only be conducted at the CDC, but testing has recently become available at a larger number of laboratories via the CDC’s International Reagent Resource (IRR) network. Signs and symptoms that would warrant diagnostic testing include fever, cough, respiratory symptoms, shortness of breath, and breathing difficulties, in the context of travel to China within the prior 14 days or a high-risk contact with an ill patient. Severe cases can lead to pneumonia, kidney failure, severe acute respiratory distress, and death, with an in-hospital mortality of approximately 4% reported by clinicians in Wuhan, the epicenter of the outbreak (Wang D, et al. JAMA. Published online February 07, 2020. doi: 10.1001/jama.2020.1585).

The influenza vaccine will not protect against 2019-nCoV, and, currently, there is no available vaccine. The best prevention is to cover your mouth and nose with a tissue or your sleeve (not your hands) when coughing or sneezing. Surgical masks are not currently recommended as protection against 2019-nCoV. Hospitalized patients should be in negative-pressure rooms under respiratory and contact precautions, with gowns, gloves, eye protection, and either N95 masks or a powered air purifying respirator (PAPR) worn by clinical staff. Human-to human transmission is reported both within and outside of China (Rothe C, et al. N Engl J Med. Published online, Jan 30, 2020. doi: 10.1056/NEJMc2001468).

Clinical updates are available via the CDC at https://www.cdc.gov/coronavirus/2019-ncov/index.html. Clinicians are advised to check frequently, given the rapidly changing state of this epidemic.

John Agapian, MD, MS, FCCP

Steering Committee Member

 

Practice operations

New Medicare billing rules bring welcome documentation relief

At the end of 2019, the Centers for Medicare and Medicaid Services (CMS) released several changes to the Medicare Physician Fee Schedule, which will go into effect starting January 1, 2021. Though the adjustments are substantial (the document outlining the revisions is nearly 2,500 pages!), there are a few that deserve highlighting.

The most significant modification contained within the policy involves revisions to E/M codes for office visits. While the changes eliminate 99201, they preserve other graded levels for visits, with increases to the relative value units (RVUs) for most levels.

The most welcome changes for clinicians are twofold. First, billing no longer needs to be based on the maddening practice of trying to meet a minimum number of points from the history and exam. Clinicians can instead now bill based on time spent. The second refreshing modification is that time-based billing need no longer be solely face-to-face but can now be based on the realities of clinical practice today, ie, reviewing information and coordinating care with others.

Dr. Timothy Dempsey
Dr. Timothy Dempsey


Thus, these re-valued levels will allow outpatient physicians to bill based on time spent on things other than the office visit, such as time to review lab work and coordinate care with other specialties.

Dr. Deep Ramachandran
Dr. Deep Ramachandran


There will also be small changes to billing for pulmonary function testing, bronchoscopy (including the option for new indications for endobronchial valves), and for “brief communications via technology.” For a recap of these and other changes coming in January 2021, CHEST and ATS have produced a free webinar which is found online at: http://www.chestnet.org/Guidelines-and-Resources/Resources/Clinical-Practice-Resources.

Timothy Dempsey, MD, MPH

Steering Committee Fellow-in-Training

Deep Ramachandran, MD, FCCP

Steering Committee Member

 

 

 

Transplant

Investigating clinical practice of lung transplantation in systemic sclerosis

Interstitial lung disease (ILD) as a sequela of systemic sclerosis (SSc) poses a significant health concern. Patients with SSc-ILD experience symptoms of shortness of breath, reduced exercise capacity, and limited activities of daily living. Inducing fibrotic parenchymal change and pulmonary hypertension, SSc-ILD presents as both the most common extra-cutaneous manifestation and cause for mortality in this cohort (Mathai et al. Springer. 2014;139). Although rare, the prognosis of SSc-ILD is both difficult to understand and complex to manage.

Dr. Clauden Louis
Dr. Clauden Louis

With lung transplant being a treatment for end stage pulmonary disease, the role for lung transplantation in SSc-ILD is considered; however, remains controversial. Published literature exist without consensus. According to the recommendations of ISHLT, SSc is to be “carefully selected,” however, for some institutions, SSc remains a relative contraindication for lung transplant as definitive therapy (Weill et al. J Heart Lung Transplant. 2014;34[1]:1). Disease-specific concerns for SSc patients following lung transplant are esophageal dysmotility, dysphagia, gastroparesis, aspiration, and reflux disease. These comorbidities are associated with worsening prognosis in transplant survival (De Cruz, et al. Curr Opin Rheumatol. 2013;25[6]:714).

As clinical practices vary significantly in the management of SSc-ILD, we will survey transplant pulmonologist and surgeons from programs listed in Scientific Registry of Transplant Recipients (SRTR). We will evaluate transplant candidacy, preoperative transplant testing, postoperative transplant care, and outcomes. With this survey, we plan to determine the key practices of lung transplant programs regarding candidacy of patients with SSc-ILD perioperative management.

Clauden Louis, MD

Fellow-in-Training Member

 

Women’s lung health

Asthma and sex hormones

Overall asthma prevalence, severity, exacerbation rate, hospitalizations, and mortality are higher among women than men. Population studies show that asthma becomes more prevalent and severe in women following puberty, particularly in women with early menarche or multiple gestations. These findings suggest that sex hormones are important to the development and severity of asthma. Additional confounding variables include obesity, exposures, atopy, and age (Zien, et al. Curr Allergy Asthma Rep. 2015;15[6]:28).

Dr. Candace Huebert
Dr. Candace Huebert


Recent studies further define the gender disparity by detailing sex hormone differences in men and women with asthma. Han and colleagues recently reported on a cross-sectional study of serum-free testosterone and estradiol levels in over 7,000 adults in the National Health and Nutrition Examination Survey (NHANES, 2013-2016) (Han, et al. Am J Respir Crit Care Med. 2020;201[2]:158).

Dr. Margaret Pisani
Dr. Margaret Pisani


Elevated free testosterone levels were associated with lower odds of current asthma in women. After stratification for obesity, elevated free testosterone and estradiol levels were associated with reduced odds of current asthma in obese women, and elevated estradiol was associated with lower odds of asthma in non-obese men. It should be noted that increased luteal phase progesterone levels have also been implicated in increasing airway hyperresponsiveness (AHR) in asthmatics (Lipworth, et al. Am J Respir Crit Care Med. 2019; Oct 22, 2019).

Dr. Jill Poole
Dr. Jill Poole

In summary, testosterone is suggested to provide a protective, anti-inflammatory effect in women with asthma (Sathish, et al. Pharmacol Ther. 2015;150:94). Obesity interaction with sex hormones highlights its role as an important risk factor and disease modifier (Peters, et al. J Allergy Clin Immunol. 2018;141:1169). Future studies should continue to expand upon the role of sex hormones in relationship to multiple confounders. These insights will continue to define mechanisms that can be manipulated leading to novel pathway targeted therapies.

Candace Huebert, MD, FCCP

Margaret Pisani, MD, MPH, FCCP

Jill Poole, MD

Steering Committee Members

 

Publications
Topics
Sections

 

Disaster response and global health

Corona virus and disaster preparedness campaign

On January 28, 2020, the US Centers for Disease Control and Prevention (CDC) issued a travel advisory recommending against all nonessential travel to China, in light of the 2019 novel coronavirus (2019-nCoV) outbreak.

Shortly thereafter, a plane that flew out of China was directed to land on a US air force base in California on Friday, January 31. Since then, other US government flights have evacuated patients to military bases throughout the country. The CDC issued a federal quarantine order lasting the 14-day incubation period to these repatriated US citizens. Nearby hospitals were debriefed and command centers set up in anticipation of any required intervention.

Dr. John Agapian
Dr. John Agapian


Initial diagnostic testing for 2019-nCoV could only be conducted at the CDC, but testing has recently become available at a larger number of laboratories via the CDC’s International Reagent Resource (IRR) network. Signs and symptoms that would warrant diagnostic testing include fever, cough, respiratory symptoms, shortness of breath, and breathing difficulties, in the context of travel to China within the prior 14 days or a high-risk contact with an ill patient. Severe cases can lead to pneumonia, kidney failure, severe acute respiratory distress, and death, with an in-hospital mortality of approximately 4% reported by clinicians in Wuhan, the epicenter of the outbreak (Wang D, et al. JAMA. Published online February 07, 2020. doi: 10.1001/jama.2020.1585).

The influenza vaccine will not protect against 2019-nCoV, and, currently, there is no available vaccine. The best prevention is to cover your mouth and nose with a tissue or your sleeve (not your hands) when coughing or sneezing. Surgical masks are not currently recommended as protection against 2019-nCoV. Hospitalized patients should be in negative-pressure rooms under respiratory and contact precautions, with gowns, gloves, eye protection, and either N95 masks or a powered air purifying respirator (PAPR) worn by clinical staff. Human-to human transmission is reported both within and outside of China (Rothe C, et al. N Engl J Med. Published online, Jan 30, 2020. doi: 10.1056/NEJMc2001468).

Clinical updates are available via the CDC at https://www.cdc.gov/coronavirus/2019-ncov/index.html. Clinicians are advised to check frequently, given the rapidly changing state of this epidemic.

John Agapian, MD, MS, FCCP

Steering Committee Member

 

Practice operations

New Medicare billing rules bring welcome documentation relief

At the end of 2019, the Centers for Medicare and Medicaid Services (CMS) released several changes to the Medicare Physician Fee Schedule, which will go into effect starting January 1, 2021. Though the adjustments are substantial (the document outlining the revisions is nearly 2,500 pages!), there are a few that deserve highlighting.

The most significant modification contained within the policy involves revisions to E/M codes for office visits. While the changes eliminate 99201, they preserve other graded levels for visits, with increases to the relative value units (RVUs) for most levels.

The most welcome changes for clinicians are twofold. First, billing no longer needs to be based on the maddening practice of trying to meet a minimum number of points from the history and exam. Clinicians can instead now bill based on time spent. The second refreshing modification is that time-based billing need no longer be solely face-to-face but can now be based on the realities of clinical practice today, ie, reviewing information and coordinating care with others.

Dr. Timothy Dempsey
Dr. Timothy Dempsey


Thus, these re-valued levels will allow outpatient physicians to bill based on time spent on things other than the office visit, such as time to review lab work and coordinate care with other specialties.

Dr. Deep Ramachandran
Dr. Deep Ramachandran


There will also be small changes to billing for pulmonary function testing, bronchoscopy (including the option for new indications for endobronchial valves), and for “brief communications via technology.” For a recap of these and other changes coming in January 2021, CHEST and ATS have produced a free webinar which is found online at: http://www.chestnet.org/Guidelines-and-Resources/Resources/Clinical-Practice-Resources.

Timothy Dempsey, MD, MPH

Steering Committee Fellow-in-Training

Deep Ramachandran, MD, FCCP

Steering Committee Member

 

 

 

Transplant

Investigating clinical practice of lung transplantation in systemic sclerosis

Interstitial lung disease (ILD) as a sequela of systemic sclerosis (SSc) poses a significant health concern. Patients with SSc-ILD experience symptoms of shortness of breath, reduced exercise capacity, and limited activities of daily living. Inducing fibrotic parenchymal change and pulmonary hypertension, SSc-ILD presents as both the most common extra-cutaneous manifestation and cause for mortality in this cohort (Mathai et al. Springer. 2014;139). Although rare, the prognosis of SSc-ILD is both difficult to understand and complex to manage.

Dr. Clauden Louis
Dr. Clauden Louis

With lung transplant being a treatment for end stage pulmonary disease, the role for lung transplantation in SSc-ILD is considered; however, remains controversial. Published literature exist without consensus. According to the recommendations of ISHLT, SSc is to be “carefully selected,” however, for some institutions, SSc remains a relative contraindication for lung transplant as definitive therapy (Weill et al. J Heart Lung Transplant. 2014;34[1]:1). Disease-specific concerns for SSc patients following lung transplant are esophageal dysmotility, dysphagia, gastroparesis, aspiration, and reflux disease. These comorbidities are associated with worsening prognosis in transplant survival (De Cruz, et al. Curr Opin Rheumatol. 2013;25[6]:714).

As clinical practices vary significantly in the management of SSc-ILD, we will survey transplant pulmonologist and surgeons from programs listed in Scientific Registry of Transplant Recipients (SRTR). We will evaluate transplant candidacy, preoperative transplant testing, postoperative transplant care, and outcomes. With this survey, we plan to determine the key practices of lung transplant programs regarding candidacy of patients with SSc-ILD perioperative management.

Clauden Louis, MD

Fellow-in-Training Member

 

Women’s lung health

Asthma and sex hormones

Overall asthma prevalence, severity, exacerbation rate, hospitalizations, and mortality are higher among women than men. Population studies show that asthma becomes more prevalent and severe in women following puberty, particularly in women with early menarche or multiple gestations. These findings suggest that sex hormones are important to the development and severity of asthma. Additional confounding variables include obesity, exposures, atopy, and age (Zien, et al. Curr Allergy Asthma Rep. 2015;15[6]:28).

Dr. Candace Huebert
Dr. Candace Huebert


Recent studies further define the gender disparity by detailing sex hormone differences in men and women with asthma. Han and colleagues recently reported on a cross-sectional study of serum-free testosterone and estradiol levels in over 7,000 adults in the National Health and Nutrition Examination Survey (NHANES, 2013-2016) (Han, et al. Am J Respir Crit Care Med. 2020;201[2]:158).

Dr. Margaret Pisani
Dr. Margaret Pisani


Elevated free testosterone levels were associated with lower odds of current asthma in women. After stratification for obesity, elevated free testosterone and estradiol levels were associated with reduced odds of current asthma in obese women, and elevated estradiol was associated with lower odds of asthma in non-obese men. It should be noted that increased luteal phase progesterone levels have also been implicated in increasing airway hyperresponsiveness (AHR) in asthmatics (Lipworth, et al. Am J Respir Crit Care Med. 2019; Oct 22, 2019).

Dr. Jill Poole
Dr. Jill Poole

In summary, testosterone is suggested to provide a protective, anti-inflammatory effect in women with asthma (Sathish, et al. Pharmacol Ther. 2015;150:94). Obesity interaction with sex hormones highlights its role as an important risk factor and disease modifier (Peters, et al. J Allergy Clin Immunol. 2018;141:1169). Future studies should continue to expand upon the role of sex hormones in relationship to multiple confounders. These insights will continue to define mechanisms that can be manipulated leading to novel pathway targeted therapies.

Candace Huebert, MD, FCCP

Margaret Pisani, MD, MPH, FCCP

Jill Poole, MD

Steering Committee Members

 

 

Disaster response and global health

Corona virus and disaster preparedness campaign

On January 28, 2020, the US Centers for Disease Control and Prevention (CDC) issued a travel advisory recommending against all nonessential travel to China, in light of the 2019 novel coronavirus (2019-nCoV) outbreak.

Shortly thereafter, a plane that flew out of China was directed to land on a US air force base in California on Friday, January 31. Since then, other US government flights have evacuated patients to military bases throughout the country. The CDC issued a federal quarantine order lasting the 14-day incubation period to these repatriated US citizens. Nearby hospitals were debriefed and command centers set up in anticipation of any required intervention.

Dr. John Agapian
Dr. John Agapian


Initial diagnostic testing for 2019-nCoV could only be conducted at the CDC, but testing has recently become available at a larger number of laboratories via the CDC’s International Reagent Resource (IRR) network. Signs and symptoms that would warrant diagnostic testing include fever, cough, respiratory symptoms, shortness of breath, and breathing difficulties, in the context of travel to China within the prior 14 days or a high-risk contact with an ill patient. Severe cases can lead to pneumonia, kidney failure, severe acute respiratory distress, and death, with an in-hospital mortality of approximately 4% reported by clinicians in Wuhan, the epicenter of the outbreak (Wang D, et al. JAMA. Published online February 07, 2020. doi: 10.1001/jama.2020.1585).

The influenza vaccine will not protect against 2019-nCoV, and, currently, there is no available vaccine. The best prevention is to cover your mouth and nose with a tissue or your sleeve (not your hands) when coughing or sneezing. Surgical masks are not currently recommended as protection against 2019-nCoV. Hospitalized patients should be in negative-pressure rooms under respiratory and contact precautions, with gowns, gloves, eye protection, and either N95 masks or a powered air purifying respirator (PAPR) worn by clinical staff. Human-to human transmission is reported both within and outside of China (Rothe C, et al. N Engl J Med. Published online, Jan 30, 2020. doi: 10.1056/NEJMc2001468).

Clinical updates are available via the CDC at https://www.cdc.gov/coronavirus/2019-ncov/index.html. Clinicians are advised to check frequently, given the rapidly changing state of this epidemic.

John Agapian, MD, MS, FCCP

Steering Committee Member

 

Practice operations

New Medicare billing rules bring welcome documentation relief

At the end of 2019, the Centers for Medicare and Medicaid Services (CMS) released several changes to the Medicare Physician Fee Schedule, which will go into effect starting January 1, 2021. Though the adjustments are substantial (the document outlining the revisions is nearly 2,500 pages!), there are a few that deserve highlighting.

The most significant modification contained within the policy involves revisions to E/M codes for office visits. While the changes eliminate 99201, they preserve other graded levels for visits, with increases to the relative value units (RVUs) for most levels.

The most welcome changes for clinicians are twofold. First, billing no longer needs to be based on the maddening practice of trying to meet a minimum number of points from the history and exam. Clinicians can instead now bill based on time spent. The second refreshing modification is that time-based billing need no longer be solely face-to-face but can now be based on the realities of clinical practice today, ie, reviewing information and coordinating care with others.

Dr. Timothy Dempsey
Dr. Timothy Dempsey


Thus, these re-valued levels will allow outpatient physicians to bill based on time spent on things other than the office visit, such as time to review lab work and coordinate care with other specialties.

Dr. Deep Ramachandran
Dr. Deep Ramachandran


There will also be small changes to billing for pulmonary function testing, bronchoscopy (including the option for new indications for endobronchial valves), and for “brief communications via technology.” For a recap of these and other changes coming in January 2021, CHEST and ATS have produced a free webinar which is found online at: http://www.chestnet.org/Guidelines-and-Resources/Resources/Clinical-Practice-Resources.

Timothy Dempsey, MD, MPH

Steering Committee Fellow-in-Training

Deep Ramachandran, MD, FCCP

Steering Committee Member

 

 

 

Transplant

Investigating clinical practice of lung transplantation in systemic sclerosis

Interstitial lung disease (ILD) as a sequela of systemic sclerosis (SSc) poses a significant health concern. Patients with SSc-ILD experience symptoms of shortness of breath, reduced exercise capacity, and limited activities of daily living. Inducing fibrotic parenchymal change and pulmonary hypertension, SSc-ILD presents as both the most common extra-cutaneous manifestation and cause for mortality in this cohort (Mathai et al. Springer. 2014;139). Although rare, the prognosis of SSc-ILD is both difficult to understand and complex to manage.

Dr. Clauden Louis
Dr. Clauden Louis

With lung transplant being a treatment for end stage pulmonary disease, the role for lung transplantation in SSc-ILD is considered; however, remains controversial. Published literature exist without consensus. According to the recommendations of ISHLT, SSc is to be “carefully selected,” however, for some institutions, SSc remains a relative contraindication for lung transplant as definitive therapy (Weill et al. J Heart Lung Transplant. 2014;34[1]:1). Disease-specific concerns for SSc patients following lung transplant are esophageal dysmotility, dysphagia, gastroparesis, aspiration, and reflux disease. These comorbidities are associated with worsening prognosis in transplant survival (De Cruz, et al. Curr Opin Rheumatol. 2013;25[6]:714).

As clinical practices vary significantly in the management of SSc-ILD, we will survey transplant pulmonologist and surgeons from programs listed in Scientific Registry of Transplant Recipients (SRTR). We will evaluate transplant candidacy, preoperative transplant testing, postoperative transplant care, and outcomes. With this survey, we plan to determine the key practices of lung transplant programs regarding candidacy of patients with SSc-ILD perioperative management.

Clauden Louis, MD

Fellow-in-Training Member

 

Women’s lung health

Asthma and sex hormones

Overall asthma prevalence, severity, exacerbation rate, hospitalizations, and mortality are higher among women than men. Population studies show that asthma becomes more prevalent and severe in women following puberty, particularly in women with early menarche or multiple gestations. These findings suggest that sex hormones are important to the development and severity of asthma. Additional confounding variables include obesity, exposures, atopy, and age (Zien, et al. Curr Allergy Asthma Rep. 2015;15[6]:28).

Dr. Candace Huebert
Dr. Candace Huebert


Recent studies further define the gender disparity by detailing sex hormone differences in men and women with asthma. Han and colleagues recently reported on a cross-sectional study of serum-free testosterone and estradiol levels in over 7,000 adults in the National Health and Nutrition Examination Survey (NHANES, 2013-2016) (Han, et al. Am J Respir Crit Care Med. 2020;201[2]:158).

Dr. Margaret Pisani
Dr. Margaret Pisani


Elevated free testosterone levels were associated with lower odds of current asthma in women. After stratification for obesity, elevated free testosterone and estradiol levels were associated with reduced odds of current asthma in obese women, and elevated estradiol was associated with lower odds of asthma in non-obese men. It should be noted that increased luteal phase progesterone levels have also been implicated in increasing airway hyperresponsiveness (AHR) in asthmatics (Lipworth, et al. Am J Respir Crit Care Med. 2019; Oct 22, 2019).

Dr. Jill Poole
Dr. Jill Poole

In summary, testosterone is suggested to provide a protective, anti-inflammatory effect in women with asthma (Sathish, et al. Pharmacol Ther. 2015;150:94). Obesity interaction with sex hormones highlights its role as an important risk factor and disease modifier (Peters, et al. J Allergy Clin Immunol. 2018;141:1169). Future studies should continue to expand upon the role of sex hormones in relationship to multiple confounders. These insights will continue to define mechanisms that can be manipulated leading to novel pathway targeted therapies.

Candace Huebert, MD, FCCP

Margaret Pisani, MD, MPH, FCCP

Jill Poole, MD

Steering Committee Members

 

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