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Improving the ability of people with schizophrenia to perform tasks that are important to daily functioning is a key component for any therapeutic intervention, a cross-sectional study of 740 patients shows.
“Our study confirms that [the four domains of] social cognition, neurocognition, resilience, and real-life functioning represent robust and independent constructs,” wrote Silvana Galderisi, MD, and her associates. The report was published in JAMA Psychiatry.
Dr. Galderisi and her associates recruited community-dwelling patients with schizophrenia as defined in the DSM-IV over an 18-month period. The patients were stabilized on antipsychotics and were seen in the outpatient units of 26 psychiatric clinics and/or mental health departments in Italy.
Several measures were administered, including the Brief Negative Symptom Scale (BNSS), the Calgary Depression Scale for Schizophrenia (CDSS), the Measurement and Treatment Research to Improve Cognition in Schizophrenia Consensus Cognitive Battery (MCCB), and the Positive and Negative Syndrome Scale (PANSS).
Using network analysis, the researchers analyzed the results found by the measures and the relationships between the four domains. “The study clearly shows that functional capacity and everyday life skills play a key role,” Dr. Galderisi and her associates wrote. “Functional capacity ... links neurocognition and social cognition with real-life functioning nodes, in particular with everyday life skills, such as household activities, handling of personal finances, and use of the telephone or public transportation.”
Dr. Galderisi and her associates said their findings show that patients with schizophrenia need treatment that goes beyond antipsychotics. “Therefore, with schizophrenia,” they wrote.
Read the full study in JAMA Psychiatry. 2018 Feb 14. doi: 10.1001/jamapsychiatry.2017.4607.
Improving the ability of people with schizophrenia to perform tasks that are important to daily functioning is a key component for any therapeutic intervention, a cross-sectional study of 740 patients shows.
“Our study confirms that [the four domains of] social cognition, neurocognition, resilience, and real-life functioning represent robust and independent constructs,” wrote Silvana Galderisi, MD, and her associates. The report was published in JAMA Psychiatry.
Dr. Galderisi and her associates recruited community-dwelling patients with schizophrenia as defined in the DSM-IV over an 18-month period. The patients were stabilized on antipsychotics and were seen in the outpatient units of 26 psychiatric clinics and/or mental health departments in Italy.
Several measures were administered, including the Brief Negative Symptom Scale (BNSS), the Calgary Depression Scale for Schizophrenia (CDSS), the Measurement and Treatment Research to Improve Cognition in Schizophrenia Consensus Cognitive Battery (MCCB), and the Positive and Negative Syndrome Scale (PANSS).
Using network analysis, the researchers analyzed the results found by the measures and the relationships between the four domains. “The study clearly shows that functional capacity and everyday life skills play a key role,” Dr. Galderisi and her associates wrote. “Functional capacity ... links neurocognition and social cognition with real-life functioning nodes, in particular with everyday life skills, such as household activities, handling of personal finances, and use of the telephone or public transportation.”
Dr. Galderisi and her associates said their findings show that patients with schizophrenia need treatment that goes beyond antipsychotics. “Therefore, with schizophrenia,” they wrote.
Read the full study in JAMA Psychiatry. 2018 Feb 14. doi: 10.1001/jamapsychiatry.2017.4607.
Improving the ability of people with schizophrenia to perform tasks that are important to daily functioning is a key component for any therapeutic intervention, a cross-sectional study of 740 patients shows.
“Our study confirms that [the four domains of] social cognition, neurocognition, resilience, and real-life functioning represent robust and independent constructs,” wrote Silvana Galderisi, MD, and her associates. The report was published in JAMA Psychiatry.
Dr. Galderisi and her associates recruited community-dwelling patients with schizophrenia as defined in the DSM-IV over an 18-month period. The patients were stabilized on antipsychotics and were seen in the outpatient units of 26 psychiatric clinics and/or mental health departments in Italy.
Several measures were administered, including the Brief Negative Symptom Scale (BNSS), the Calgary Depression Scale for Schizophrenia (CDSS), the Measurement and Treatment Research to Improve Cognition in Schizophrenia Consensus Cognitive Battery (MCCB), and the Positive and Negative Syndrome Scale (PANSS).
Using network analysis, the researchers analyzed the results found by the measures and the relationships between the four domains. “The study clearly shows that functional capacity and everyday life skills play a key role,” Dr. Galderisi and her associates wrote. “Functional capacity ... links neurocognition and social cognition with real-life functioning nodes, in particular with everyday life skills, such as household activities, handling of personal finances, and use of the telephone or public transportation.”
Dr. Galderisi and her associates said their findings show that patients with schizophrenia need treatment that goes beyond antipsychotics. “Therefore, with schizophrenia,” they wrote.
Read the full study in JAMA Psychiatry. 2018 Feb 14. doi: 10.1001/jamapsychiatry.2017.4607.
FROM JAMA PSYCHIATRY