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LOS ANGELES — Surveillance data indicate that 10% of people in the United States who become infected with HIV have acquired a virus with some resistance, Dr. Ulana Bodnar said at the 14th Conference on Retroviruses and Opportunistic Infections.
The 11-state survey represents the largest survey done to date regarding HIV resistance. The survey, which looked at specimens from 3,130 newly diagnosed, drug-naive individuals, found that 4% of infections had mutations conferring resistance to nucleoside reverse transcriptase inhibitors, 7% to nonnucleoside reverse transcriptase inhibitors, and 2% to protease inhibitors.
The percentages add up to more than 10% because some viruses were resistant to more than one class of drug.
Multidrug resistance was found in 2% of individuals, with 0.5% having resistance to drugs in all three classes, reported Dr. Bodnar, of the Centers for Disease Control and Prevention, Atlanta.
Overall, 94% were infected with subtype B virus. After subtype B, subtypes C and CRF02-AG were the most common, accounting for 2% and 1% of the infections, respectively, he said in a poster presentation.
The non-B variants were somewhat less likely to have resistance than were the B subtypes (8% vs. 11%); however, the ?difference was not statistically significant.
The findings of the survey “are consistent with what other studies have shown over the past 5 years,” Dr. Bodnar said in an interview. “It is a good baseline with which to consider the data we get down the road.”
The 11 states included in the survey were Colorado, Illinois, Louisiana, Maryland, Massachusetts, Michigan, Mississippi, North Carolina, South Carolina, Virginia, and Washington. The specimens came from a total of 409 sites.
LOS ANGELES — Surveillance data indicate that 10% of people in the United States who become infected with HIV have acquired a virus with some resistance, Dr. Ulana Bodnar said at the 14th Conference on Retroviruses and Opportunistic Infections.
The 11-state survey represents the largest survey done to date regarding HIV resistance. The survey, which looked at specimens from 3,130 newly diagnosed, drug-naive individuals, found that 4% of infections had mutations conferring resistance to nucleoside reverse transcriptase inhibitors, 7% to nonnucleoside reverse transcriptase inhibitors, and 2% to protease inhibitors.
The percentages add up to more than 10% because some viruses were resistant to more than one class of drug.
Multidrug resistance was found in 2% of individuals, with 0.5% having resistance to drugs in all three classes, reported Dr. Bodnar, of the Centers for Disease Control and Prevention, Atlanta.
Overall, 94% were infected with subtype B virus. After subtype B, subtypes C and CRF02-AG were the most common, accounting for 2% and 1% of the infections, respectively, he said in a poster presentation.
The non-B variants were somewhat less likely to have resistance than were the B subtypes (8% vs. 11%); however, the ?difference was not statistically significant.
The findings of the survey “are consistent with what other studies have shown over the past 5 years,” Dr. Bodnar said in an interview. “It is a good baseline with which to consider the data we get down the road.”
The 11 states included in the survey were Colorado, Illinois, Louisiana, Maryland, Massachusetts, Michigan, Mississippi, North Carolina, South Carolina, Virginia, and Washington. The specimens came from a total of 409 sites.
LOS ANGELES — Surveillance data indicate that 10% of people in the United States who become infected with HIV have acquired a virus with some resistance, Dr. Ulana Bodnar said at the 14th Conference on Retroviruses and Opportunistic Infections.
The 11-state survey represents the largest survey done to date regarding HIV resistance. The survey, which looked at specimens from 3,130 newly diagnosed, drug-naive individuals, found that 4% of infections had mutations conferring resistance to nucleoside reverse transcriptase inhibitors, 7% to nonnucleoside reverse transcriptase inhibitors, and 2% to protease inhibitors.
The percentages add up to more than 10% because some viruses were resistant to more than one class of drug.
Multidrug resistance was found in 2% of individuals, with 0.5% having resistance to drugs in all three classes, reported Dr. Bodnar, of the Centers for Disease Control and Prevention, Atlanta.
Overall, 94% were infected with subtype B virus. After subtype B, subtypes C and CRF02-AG were the most common, accounting for 2% and 1% of the infections, respectively, he said in a poster presentation.
The non-B variants were somewhat less likely to have resistance than were the B subtypes (8% vs. 11%); however, the ?difference was not statistically significant.
The findings of the survey “are consistent with what other studies have shown over the past 5 years,” Dr. Bodnar said in an interview. “It is a good baseline with which to consider the data we get down the road.”
The 11 states included in the survey were Colorado, Illinois, Louisiana, Maryland, Massachusetts, Michigan, Mississippi, North Carolina, South Carolina, Virginia, and Washington. The specimens came from a total of 409 sites.