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Summit Directors and Editors:
Michael A. DeGeorgia, MD; Derk Krieger, MD, PhD; and Anthony Furlan, MD
Contents
Foreword
Michael DeGeorgia, MD
Historical Perspectives: Neurointensive Care
The development of neurologic intensive care
Allan H. Ropper, MD, St. Elizabeth's Medical Center and Tufts University School of Medicine, Boston, MA
Intracranial Pressure
The pathophysiology of brain edema and elevated intracranial pressure
Anthony Marmarou, PhD, Virginia Commonwealth University Medical Center, Richmond, VA
Hypertonic saline for cerebral edema and elevated intracranial pressure
José I. Suarez, MD, University Hospitals of Cleveland and Case Western Reserve University, Cleveland, OH
Every breath you take: Hyperventilation and intracranial pressure
Claudia Robertson, MD, Baylor College of Medicine, Houston, TX
Multimodal monitoring in neurocritical care
Michael A. DeGeorgia, MD, The Cleveland Clinic Foundation, Cleveland, OH
Hemorrhagic Stroke
Endovascular coiling: The end of conventional neurosurgery?
Peter A. Rasmussen, MD, The Cleveland Clinic Foundation, Cleveland, OH
Fundamentals of Cricital Care
Lessons from the medical and surgical ICU
J. Javier Provencio, MD, The Cleveland Clinic Foundation, Cleveland, OH
Historical Perspectives: Cerebrovascular Disease
Cerebrovascular disease: Historical background, with an eye to the future
Louis R. Caplan, MD, Harvard Medical School and Beth Israel Deaconess Medical Center, Boston, MA
Acute Ischemic Stroke
Pathophysiology of acute ischemic stroke
Midori A. Yenari, MD, Stanford University, Stanford, CA
Intravenous thrombolysis for acute stroke
Joseph P. Broderick, MD, University of Cincinnati College of Medicine, Cincinnati, OH
Intra-arterial thrombolysis for acute stroke
Anthony Furlan, MD, The Cleveland Clinic Foundation, Cleveland, OH
Therapeutic hypothermia may enhance reperfusion in acute ischemic stroke
Derk W. Krieger, MD, PhD, The Cleveland Clinic Foundation, Cleveland, OH
Stem cell transplantation for stroke
Lawrence R. Wechsler, MD, University of Pittsburgh Medical School, Pittsburgh, PA
Extracranial Disease
Carotid artery disease: From knife to stent
Marc R. Mayberg, MD, The Cleveland Clinic Foundation, Cleveland, OH
Carotid stenting in high-risk patients: Design and rationale of the SAPPHIRE trial
Jay S. Yadav, MD, The Cleveland Clinic Foundation, Cleveland, OH
Intracranial Disease
Medical management of intracranial atherosclerosis: Current state of the art
Cathy A. Sila, MD, The Cleveland Clinic Foundation, Cleveland, OH
Intracranial stentings: Which patients and when?
Randall T. Higashida, MD, University of California, San Francisco, Medical Center, San Francisco, CA
Antithrombotic Therapy
Anticoagulation for stroke prevention: Yes, no, maybe
J.P. Mohr, MD, The Neurological Institute, New York, NY
Antiplatelet therapy for acute stroke: Aspirin and beyond
Cathy A. Sila, MD, The Cleveland Clinic Foundation, Cleveland, OH
Abstracts/Poster Presentations
Abstract 1: Hyponatremia-related focal cerebral edema, a mimic of worsening cerebral edema due to intracerebral hemorrhage
P. Widdes-Walsh, V. Sabharwal
Abstract 2: Suboccipital craniectomy for acute cerebellar ischemic stroke
B.R. Cohen, G.L. Bernardini, D. Friedlich, A.J. Popp
Abstract 3: The feasibility and safety of mild brain hypothermia obtained by local surface cooling in acute stroke
K. Yamada, H. Moriwaki, H. Oe, K. Miyashita, K. Nagatsuka, T. Yamawaki, H. Naritomi
Abstract 4: The Diverter, a novel permanent arterial diversion device
J. Leor, Y. Grad, O. Oz, Y. Assaf
Abstract 5: Fatal arrhythmia in an anxious patient during recovery from lateral medullary infarction
J.G. Lattore
Abstract 6: Motor, behavioral, and cognitive changes in patients with thalamic lesions
A.V. Srinivasan, B.S. Virudhagirinathan, C.U. Velmurugendran
Abstract 7: Reversal of locked-in syndrome with anticoagulation, induced hypertension, and intravenous t-PA
K.E. Wartenberg, N.S. Janjua, S.A. Mayer, P. Meyers
Abstract 8: Dantrolene reduces the threshold and gain for shivering
R. Lenhardt
Abstract 9: Predicting outcome after subarachnoid hemorrhage: Comparison of different grading systems
M. Berker, A. Deogaonkar, V. Sabharwal, P. Rasmussen, M. Mayberg, M. DeGeorgia
Abstract 10: Integrative monitoring methods in neurocricital care
A. Deogaonkar, A. Vander Kouwe, K. Horning, R. Burgess, M. DeGerogia
Summit Directors and Editors:
Michael A. DeGeorgia, MD; Derk Krieger, MD, PhD; and Anthony Furlan, MD
Contents
Foreword
Michael DeGeorgia, MD
Historical Perspectives: Neurointensive Care
The development of neurologic intensive care
Allan H. Ropper, MD, St. Elizabeth's Medical Center and Tufts University School of Medicine, Boston, MA
Intracranial Pressure
The pathophysiology of brain edema and elevated intracranial pressure
Anthony Marmarou, PhD, Virginia Commonwealth University Medical Center, Richmond, VA
Hypertonic saline for cerebral edema and elevated intracranial pressure
José I. Suarez, MD, University Hospitals of Cleveland and Case Western Reserve University, Cleveland, OH
Every breath you take: Hyperventilation and intracranial pressure
Claudia Robertson, MD, Baylor College of Medicine, Houston, TX
Multimodal monitoring in neurocritical care
Michael A. DeGeorgia, MD, The Cleveland Clinic Foundation, Cleveland, OH
Hemorrhagic Stroke
Endovascular coiling: The end of conventional neurosurgery?
Peter A. Rasmussen, MD, The Cleveland Clinic Foundation, Cleveland, OH
Fundamentals of Cricital Care
Lessons from the medical and surgical ICU
J. Javier Provencio, MD, The Cleveland Clinic Foundation, Cleveland, OH
Historical Perspectives: Cerebrovascular Disease
Cerebrovascular disease: Historical background, with an eye to the future
Louis R. Caplan, MD, Harvard Medical School and Beth Israel Deaconess Medical Center, Boston, MA
Acute Ischemic Stroke
Pathophysiology of acute ischemic stroke
Midori A. Yenari, MD, Stanford University, Stanford, CA
Intravenous thrombolysis for acute stroke
Joseph P. Broderick, MD, University of Cincinnati College of Medicine, Cincinnati, OH
Intra-arterial thrombolysis for acute stroke
Anthony Furlan, MD, The Cleveland Clinic Foundation, Cleveland, OH
Therapeutic hypothermia may enhance reperfusion in acute ischemic stroke
Derk W. Krieger, MD, PhD, The Cleveland Clinic Foundation, Cleveland, OH
Stem cell transplantation for stroke
Lawrence R. Wechsler, MD, University of Pittsburgh Medical School, Pittsburgh, PA
Extracranial Disease
Carotid artery disease: From knife to stent
Marc R. Mayberg, MD, The Cleveland Clinic Foundation, Cleveland, OH
Carotid stenting in high-risk patients: Design and rationale of the SAPPHIRE trial
Jay S. Yadav, MD, The Cleveland Clinic Foundation, Cleveland, OH
Intracranial Disease
Medical management of intracranial atherosclerosis: Current state of the art
Cathy A. Sila, MD, The Cleveland Clinic Foundation, Cleveland, OH
Intracranial stentings: Which patients and when?
Randall T. Higashida, MD, University of California, San Francisco, Medical Center, San Francisco, CA
Antithrombotic Therapy
Anticoagulation for stroke prevention: Yes, no, maybe
J.P. Mohr, MD, The Neurological Institute, New York, NY
Antiplatelet therapy for acute stroke: Aspirin and beyond
Cathy A. Sila, MD, The Cleveland Clinic Foundation, Cleveland, OH
Abstracts/Poster Presentations
Abstract 1: Hyponatremia-related focal cerebral edema, a mimic of worsening cerebral edema due to intracerebral hemorrhage
P. Widdes-Walsh, V. Sabharwal
Abstract 2: Suboccipital craniectomy for acute cerebellar ischemic stroke
B.R. Cohen, G.L. Bernardini, D. Friedlich, A.J. Popp
Abstract 3: The feasibility and safety of mild brain hypothermia obtained by local surface cooling in acute stroke
K. Yamada, H. Moriwaki, H. Oe, K. Miyashita, K. Nagatsuka, T. Yamawaki, H. Naritomi
Abstract 4: The Diverter, a novel permanent arterial diversion device
J. Leor, Y. Grad, O. Oz, Y. Assaf
Abstract 5: Fatal arrhythmia in an anxious patient during recovery from lateral medullary infarction
J.G. Lattore
Abstract 6: Motor, behavioral, and cognitive changes in patients with thalamic lesions
A.V. Srinivasan, B.S. Virudhagirinathan, C.U. Velmurugendran
Abstract 7: Reversal of locked-in syndrome with anticoagulation, induced hypertension, and intravenous t-PA
K.E. Wartenberg, N.S. Janjua, S.A. Mayer, P. Meyers
Abstract 8: Dantrolene reduces the threshold and gain for shivering
R. Lenhardt
Abstract 9: Predicting outcome after subarachnoid hemorrhage: Comparison of different grading systems
M. Berker, A. Deogaonkar, V. Sabharwal, P. Rasmussen, M. Mayberg, M. DeGeorgia
Abstract 10: Integrative monitoring methods in neurocricital care
A. Deogaonkar, A. Vander Kouwe, K. Horning, R. Burgess, M. DeGerogia
Summit Directors and Editors:
Michael A. DeGeorgia, MD; Derk Krieger, MD, PhD; and Anthony Furlan, MD
Contents
Foreword
Michael DeGeorgia, MD
Historical Perspectives: Neurointensive Care
The development of neurologic intensive care
Allan H. Ropper, MD, St. Elizabeth's Medical Center and Tufts University School of Medicine, Boston, MA
Intracranial Pressure
The pathophysiology of brain edema and elevated intracranial pressure
Anthony Marmarou, PhD, Virginia Commonwealth University Medical Center, Richmond, VA
Hypertonic saline for cerebral edema and elevated intracranial pressure
José I. Suarez, MD, University Hospitals of Cleveland and Case Western Reserve University, Cleveland, OH
Every breath you take: Hyperventilation and intracranial pressure
Claudia Robertson, MD, Baylor College of Medicine, Houston, TX
Multimodal monitoring in neurocritical care
Michael A. DeGeorgia, MD, The Cleveland Clinic Foundation, Cleveland, OH
Hemorrhagic Stroke
Endovascular coiling: The end of conventional neurosurgery?
Peter A. Rasmussen, MD, The Cleveland Clinic Foundation, Cleveland, OH
Fundamentals of Cricital Care
Lessons from the medical and surgical ICU
J. Javier Provencio, MD, The Cleveland Clinic Foundation, Cleveland, OH
Historical Perspectives: Cerebrovascular Disease
Cerebrovascular disease: Historical background, with an eye to the future
Louis R. Caplan, MD, Harvard Medical School and Beth Israel Deaconess Medical Center, Boston, MA
Acute Ischemic Stroke
Pathophysiology of acute ischemic stroke
Midori A. Yenari, MD, Stanford University, Stanford, CA
Intravenous thrombolysis for acute stroke
Joseph P. Broderick, MD, University of Cincinnati College of Medicine, Cincinnati, OH
Intra-arterial thrombolysis for acute stroke
Anthony Furlan, MD, The Cleveland Clinic Foundation, Cleveland, OH
Therapeutic hypothermia may enhance reperfusion in acute ischemic stroke
Derk W. Krieger, MD, PhD, The Cleveland Clinic Foundation, Cleveland, OH
Stem cell transplantation for stroke
Lawrence R. Wechsler, MD, University of Pittsburgh Medical School, Pittsburgh, PA
Extracranial Disease
Carotid artery disease: From knife to stent
Marc R. Mayberg, MD, The Cleveland Clinic Foundation, Cleveland, OH
Carotid stenting in high-risk patients: Design and rationale of the SAPPHIRE trial
Jay S. Yadav, MD, The Cleveland Clinic Foundation, Cleveland, OH
Intracranial Disease
Medical management of intracranial atherosclerosis: Current state of the art
Cathy A. Sila, MD, The Cleveland Clinic Foundation, Cleveland, OH
Intracranial stentings: Which patients and when?
Randall T. Higashida, MD, University of California, San Francisco, Medical Center, San Francisco, CA
Antithrombotic Therapy
Anticoagulation for stroke prevention: Yes, no, maybe
J.P. Mohr, MD, The Neurological Institute, New York, NY
Antiplatelet therapy for acute stroke: Aspirin and beyond
Cathy A. Sila, MD, The Cleveland Clinic Foundation, Cleveland, OH
Abstracts/Poster Presentations
Abstract 1: Hyponatremia-related focal cerebral edema, a mimic of worsening cerebral edema due to intracerebral hemorrhage
P. Widdes-Walsh, V. Sabharwal
Abstract 2: Suboccipital craniectomy for acute cerebellar ischemic stroke
B.R. Cohen, G.L. Bernardini, D. Friedlich, A.J. Popp
Abstract 3: The feasibility and safety of mild brain hypothermia obtained by local surface cooling in acute stroke
K. Yamada, H. Moriwaki, H. Oe, K. Miyashita, K. Nagatsuka, T. Yamawaki, H. Naritomi
Abstract 4: The Diverter, a novel permanent arterial diversion device
J. Leor, Y. Grad, O. Oz, Y. Assaf
Abstract 5: Fatal arrhythmia in an anxious patient during recovery from lateral medullary infarction
J.G. Lattore
Abstract 6: Motor, behavioral, and cognitive changes in patients with thalamic lesions
A.V. Srinivasan, B.S. Virudhagirinathan, C.U. Velmurugendran
Abstract 7: Reversal of locked-in syndrome with anticoagulation, induced hypertension, and intravenous t-PA
K.E. Wartenberg, N.S. Janjua, S.A. Mayer, P. Meyers
Abstract 8: Dantrolene reduces the threshold and gain for shivering
R. Lenhardt
Abstract 9: Predicting outcome after subarachnoid hemorrhage: Comparison of different grading systems
M. Berker, A. Deogaonkar, V. Sabharwal, P. Rasmussen, M. Mayberg, M. DeGeorgia
Abstract 10: Integrative monitoring methods in neurocricital care
A. Deogaonkar, A. Vander Kouwe, K. Horning, R. Burgess, M. DeGerogia
