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In reply: Methicillin-resistant Staphylococcus aureus: A link to statin therapy?

In Reply: While there may be some theoretical increased risk of S aureus cutaneous infections because of the effect of statins on lipids in the skin, it is not clear what role statin use has played in the changing epidemiology of S aureus infections. Other studies suggest that statins may ameliorate sepsis because of their anti-inflammatory effect.1

References
  1. Almog Y, Shefer A, Novack V, et al. Prior statin therapy is associated with a decreased rate of severe sepsis. Circulation 2004; 110:880–885.
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Susan Rehm, MD
Department of Infectious Diseases, Cleveland Clinic

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Cleveland Clinic Journal of Medicine - 75(5)
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Susan Rehm, MD
Department of Infectious Diseases, Cleveland Clinic

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Susan Rehm, MD
Department of Infectious Diseases, Cleveland Clinic

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In Reply: While there may be some theoretical increased risk of S aureus cutaneous infections because of the effect of statins on lipids in the skin, it is not clear what role statin use has played in the changing epidemiology of S aureus infections. Other studies suggest that statins may ameliorate sepsis because of their anti-inflammatory effect.1

In Reply: While there may be some theoretical increased risk of S aureus cutaneous infections because of the effect of statins on lipids in the skin, it is not clear what role statin use has played in the changing epidemiology of S aureus infections. Other studies suggest that statins may ameliorate sepsis because of their anti-inflammatory effect.1

References
  1. Almog Y, Shefer A, Novack V, et al. Prior statin therapy is associated with a decreased rate of severe sepsis. Circulation 2004; 110:880–885.
References
  1. Almog Y, Shefer A, Novack V, et al. Prior statin therapy is associated with a decreased rate of severe sepsis. Circulation 2004; 110:880–885.
Issue
Cleveland Clinic Journal of Medicine - 75(5)
Issue
Cleveland Clinic Journal of Medicine - 75(5)
Page Number
328-329
Page Number
328-329
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In reply: Methicillin-resistant Staphylococcus aureus: A link to statin therapy?
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In reply: Methicillin-resistant Staphylococcus aureus: A link to statin therapy?
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