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Short QT syndrome

To the Editor: We read with great interest the article by Drs. Al Maluli and Meshkov on short QT syndrome in the January 2013 issue.1 We are wondering whether Holter monitoring and giving a beta-blocker can help in the diagnosis of this syndrome.

Compared with the normal population, patients with short QT syndrome have less variation of the QT interval in relation to the change in heart rate. This will result in misinterpretation of the corrected QT interval with a faster heart rate and subsequently false-negative diagnosis of this possibly fatal syndrome. Holter monitoring can be helpful in this situation because it allows measurement of the corrected QT interval during a period of slower heart rate, such as sleep.

Bjerregaard2 mentioned the use of a beta-blocker to slow the heart rate when measuring the corrected QT interval. According to the diagnostic criteria, a shorter corrected QT interval correlates with a higher probability of short QT syndrome. Using the above measures may reveal the true corrected QT interval and improve the diagnostic accuracy of short QT syndrome in patients with a rapid heart rate.

References
  1. Al Maluli H, Meshkov AB. A short story of the short QT syndrome. Cleve Clin J Med 2013; 80:40–47.
  2. Bjerregaard P. Proposed diagnostic criteria for short QT syndrome are badly founded. J Am Coll Cardiol 2011; 58:549–550.
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Supawat Ratanapo, MD
Bassett Medical Center, Cooperstown, NY

Narat Srivali, MD
Bassett Medical Center, Cooperstown, NY

Wisit Cheungpasitporn, MD
Bassett Medical Center, Cooperstown, NY

Saeed Ahmed, MB, BS
Bassett Medical Center, Cooperstown, NY

Promporn Suksaranjit, MD
Bassett Medical Center, Cooperstown, NY

Daych Chongnarungsin, MD
Bassett Medical Center, Cooperstown, NY

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Supawat Ratanapo, MD
Bassett Medical Center, Cooperstown, NY

Narat Srivali, MD
Bassett Medical Center, Cooperstown, NY

Wisit Cheungpasitporn, MD
Bassett Medical Center, Cooperstown, NY

Saeed Ahmed, MB, BS
Bassett Medical Center, Cooperstown, NY

Promporn Suksaranjit, MD
Bassett Medical Center, Cooperstown, NY

Daych Chongnarungsin, MD
Bassett Medical Center, Cooperstown, NY

Author and Disclosure Information

Supawat Ratanapo, MD
Bassett Medical Center, Cooperstown, NY

Narat Srivali, MD
Bassett Medical Center, Cooperstown, NY

Wisit Cheungpasitporn, MD
Bassett Medical Center, Cooperstown, NY

Saeed Ahmed, MB, BS
Bassett Medical Center, Cooperstown, NY

Promporn Suksaranjit, MD
Bassett Medical Center, Cooperstown, NY

Daych Chongnarungsin, MD
Bassett Medical Center, Cooperstown, NY

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To the Editor: We read with great interest the article by Drs. Al Maluli and Meshkov on short QT syndrome in the January 2013 issue.1 We are wondering whether Holter monitoring and giving a beta-blocker can help in the diagnosis of this syndrome.

Compared with the normal population, patients with short QT syndrome have less variation of the QT interval in relation to the change in heart rate. This will result in misinterpretation of the corrected QT interval with a faster heart rate and subsequently false-negative diagnosis of this possibly fatal syndrome. Holter monitoring can be helpful in this situation because it allows measurement of the corrected QT interval during a period of slower heart rate, such as sleep.

Bjerregaard2 mentioned the use of a beta-blocker to slow the heart rate when measuring the corrected QT interval. According to the diagnostic criteria, a shorter corrected QT interval correlates with a higher probability of short QT syndrome. Using the above measures may reveal the true corrected QT interval and improve the diagnostic accuracy of short QT syndrome in patients with a rapid heart rate.

To the Editor: We read with great interest the article by Drs. Al Maluli and Meshkov on short QT syndrome in the January 2013 issue.1 We are wondering whether Holter monitoring and giving a beta-blocker can help in the diagnosis of this syndrome.

Compared with the normal population, patients with short QT syndrome have less variation of the QT interval in relation to the change in heart rate. This will result in misinterpretation of the corrected QT interval with a faster heart rate and subsequently false-negative diagnosis of this possibly fatal syndrome. Holter monitoring can be helpful in this situation because it allows measurement of the corrected QT interval during a period of slower heart rate, such as sleep.

Bjerregaard2 mentioned the use of a beta-blocker to slow the heart rate when measuring the corrected QT interval. According to the diagnostic criteria, a shorter corrected QT interval correlates with a higher probability of short QT syndrome. Using the above measures may reveal the true corrected QT interval and improve the diagnostic accuracy of short QT syndrome in patients with a rapid heart rate.

References
  1. Al Maluli H, Meshkov AB. A short story of the short QT syndrome. Cleve Clin J Med 2013; 80:40–47.
  2. Bjerregaard P. Proposed diagnostic criteria for short QT syndrome are badly founded. J Am Coll Cardiol 2011; 58:549–550.
References
  1. Al Maluli H, Meshkov AB. A short story of the short QT syndrome. Cleve Clin J Med 2013; 80:40–47.
  2. Bjerregaard P. Proposed diagnostic criteria for short QT syndrome are badly founded. J Am Coll Cardiol 2011; 58:549–550.
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