Pharmacology
Fluoroquinolones and the Risk of Kidney Damage
Fed Pract. 2013 November;30(11):e2
Kidney injury isn’t usually a top consideration when prescribing fluoroquinolones, even though reports of acute kidney injury have been published and the product label includes renal failure as a rare but possible adverse reaction. But oral fluoroquinolones more than doubled the risk of acute kidney injury, severe enough to require hospital admission in adult men, according to researchers from the Department of Health and Human Services in Silver Spring, Maryland; the University of Florida in Gainesville; the University of British Columbia in Vancouver and McGill University Health Center in Montréal, Quebec, both in Canada; and the University of Washington in Seattle.