DDSEP® 8 Quick Quiz

July 2019 - Question 2

Q2. A 63-year-old woman is admitted with abdominal pain and iron deficiency anemia. She reports long-standing anemia and a negative workup in the past year including an upper endoscopy, colonoscopy, and video capsule endoscopy. She was started on iron infusions with a modest improvement in her anemia. Her other medical history includes osteoporosis; osteoarthritis, for which she takes over the counter NSAIDs, breast cancer (20 years ago treated with lumpectomy and local radiation); and migraines for which she takes sumatriptan once or twice a month.

Which of her medications puts her at the highest risk for peptic ulcer disease?

Iron

Sumatriptan

Alendronate

Tamoxifen

Q2. Correct answer: C

Rationale
Oral iron, and not infusions, are associated with peptic ulcer disease. Sumatriptan alone, or tamoxifen, are not known to cause ulcers.

Reference:
Miyake K., Kusunoki M., Shinji Y., et al. Bisphosphonate increases risk of gastroduodenal ulcer in rheumatoid arthritis patients on long-term nonsteroidal anti-inflammatory drug therapy. J Gastroenterol. 2009;44(2):113.

ginews@gastro.org

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