Metabolic pathway perturbation of patients with chronic heart failure and comorbid major depressive disorder

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Metabolic pathway perturbation of patients with chronic heart failure and comorbid major depressive disorder
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*Metabolomics: A global biochemical approach to the study of neuropsychiatric diseases. Metabolomics, the omics science of biochemistry, is a global approach to understanding regulation of metabolic pathways and metabolic networks of a biological system. Metabolomics complements data derived from genomics, transcriptomics, and proteomics to assist in providing a systems approach to the study of human health and disease. The metabolome defines a metabolic state as regulated by a net of interactions between genes and environment and provides useful information to bridge the gap between genotype and phenotype. Metabolomics became part of the NIH Roadmap vision in 2003 and is a rapidly expanding field.

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Wei Jiang, MD
Duke University Medical Center, Durham, NC

David Steffens, MD
Duke University Medical Center, Durham, NC

Edward Karoly, PhD
Metabolon Inc., Research Triangle Park, NC

Maragatha Kuchibhatla, PhD
Duke University Medical Center, Durham, NC

Michael S. Cuffe, MD
Duke University Medical Center, Durham, NC

Christopher M. O’Connor, MD
Duke University Medical Center, Durham, NC

Ranga Krishnan, MD
Duke University Medical Center, Durham, NC

Rima Kaddurah-Daouk, PhD
Duke University Medical Center, Durham, NC

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S96a
Author and Disclosure Information

Wei Jiang, MD
Duke University Medical Center, Durham, NC

David Steffens, MD
Duke University Medical Center, Durham, NC

Edward Karoly, PhD
Metabolon Inc., Research Triangle Park, NC

Maragatha Kuchibhatla, PhD
Duke University Medical Center, Durham, NC

Michael S. Cuffe, MD
Duke University Medical Center, Durham, NC

Christopher M. O’Connor, MD
Duke University Medical Center, Durham, NC

Ranga Krishnan, MD
Duke University Medical Center, Durham, NC

Rima Kaddurah-Daouk, PhD
Duke University Medical Center, Durham, NC

Author and Disclosure Information

Wei Jiang, MD
Duke University Medical Center, Durham, NC

David Steffens, MD
Duke University Medical Center, Durham, NC

Edward Karoly, PhD
Metabolon Inc., Research Triangle Park, NC

Maragatha Kuchibhatla, PhD
Duke University Medical Center, Durham, NC

Michael S. Cuffe, MD
Duke University Medical Center, Durham, NC

Christopher M. O’Connor, MD
Duke University Medical Center, Durham, NC

Ranga Krishnan, MD
Duke University Medical Center, Durham, NC

Rima Kaddurah-Daouk, PhD
Duke University Medical Center, Durham, NC

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References

*Metabolomics: A global biochemical approach to the study of neuropsychiatric diseases. Metabolomics, the omics science of biochemistry, is a global approach to understanding regulation of metabolic pathways and metabolic networks of a biological system. Metabolomics complements data derived from genomics, transcriptomics, and proteomics to assist in providing a systems approach to the study of human health and disease. The metabolome defines a metabolic state as regulated by a net of interactions between genes and environment and provides useful information to bridge the gap between genotype and phenotype. Metabolomics became part of the NIH Roadmap vision in 2003 and is a rapidly expanding field.

References

*Metabolomics: A global biochemical approach to the study of neuropsychiatric diseases. Metabolomics, the omics science of biochemistry, is a global approach to understanding regulation of metabolic pathways and metabolic networks of a biological system. Metabolomics complements data derived from genomics, transcriptomics, and proteomics to assist in providing a systems approach to the study of human health and disease. The metabolome defines a metabolic state as regulated by a net of interactions between genes and environment and provides useful information to bridge the gap between genotype and phenotype. Metabolomics became part of the NIH Roadmap vision in 2003 and is a rapidly expanding field.

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S96a
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S96a
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Metabolic pathway perturbation of patients with chronic heart failure and comorbid major depressive disorder
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Metabolic pathway perturbation of patients with chronic heart failure and comorbid major depressive disorder
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Cleveland Clinic Journal of Medicine 2011 August;78(suppl 1):S96a
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