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We read with interest the article by Maxwell and Mirza.1 We appreciate using the large National Surgical Quality Improvement Project (NSQIP) database to assess comanagement outcomes, although we have concerns about the study design. Propensity score–matching (PSM) studies are limited; PSMs generate an average effect that neither establishes whether a treatment is optimal for a given patient nor control for unmeasured confounders.2 Some baseline characteristics suggest that the comanaged and noncomanaged populations are quite different and, therefore, likely had unmeasured confounders that contributed to not detecting true effects. Also, as suggested by the authors, the NSQIP definitions of comanagement and standardized hip fracture program are broad. Recent studies in hip fracture comanagement attribute best outcomes to an organized program, shared decision making, expert comanagers, and each service having full responsibility including writing their own orders.3-5 As no large database captures this distinction, it is not yet possible to perform a large, multicenter analysis. This type of comanagement cannot be studied in a randomized controlled trial. We recommend caution in overinterpreting the conclusions because there is substantial evidence in favor of optimized comanagement.

References

1. Maxwell BG, Mirza A. Medical comanagement of hip fracture patients is not associated with superior perioperative outcomes: a propensity score-matched retrospective cohort analysis of the National Surgical Quality Improvement Project J Hosp Med. 2020;15:468-474. https://doi.org/10.12788/jhm.3343
2. Benedetto U, Head SJ, Angelini GD, Blackstone EH. Statistical primer: propensity score matching and its alternatives. Eur J Cardiothorac Surg. 2018;53(6):1112-1117. https://doi.org/10.1093/ejcts/ezy167
3. Friedman SM, Mendelson DA, Kates SL, McCann RM. Geriatric co-management of proximal femur fractures: total quality management and protocol-­driven care result in better outcomes for a frail patient population. J Am Geriatr Soc. 2008;56(7):1349-1356. https://doi.org/10.1111/j.1532-5415.2008.01770.x
4. Schnell S, Friedman SM, Mendelson DA, Bingham KW, Kates SL. The 1-year mortality of patients treated in a hip fracture program for elders. Geriatr Orthop Surg Rehabil. 2010;1(1):6-14. https://doi.org/10.1177/2151458510378105
5. Mendelson DA, Friedman SM. Principles of comanagement and the geriatric fracture center. Clin Geriatr Med. 2014;30(2):183-189. https://doi.org/10.1016/j.cger.2014.01.016

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1Konar Professor of Geriatrics & Palliative Care, School of Medicine & Dentistry, University of Rochester, Rochester, New York; 2Geriatric Fracture Center, Highland Hospital, Rochester, New York; 3Orthopaedic Surgery, Brown University, Providence, Rhode Island; 4Trauma Orthopedics, Rhode Island Hospital, Providence, Rhode Island; 5Institute of Health Innovations & Outcomes Research, Feinstein Institutes for Medical Research, Manhasset, New York; 6Geriatric Hospitalist Service, Northwell Health, Manhasset, New York; 7Medicine, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Hempstead, New York.

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The authors have nothing to disclose.

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1Konar Professor of Geriatrics & Palliative Care, School of Medicine & Dentistry, University of Rochester, Rochester, New York; 2Geriatric Fracture Center, Highland Hospital, Rochester, New York; 3Orthopaedic Surgery, Brown University, Providence, Rhode Island; 4Trauma Orthopedics, Rhode Island Hospital, Providence, Rhode Island; 5Institute of Health Innovations & Outcomes Research, Feinstein Institutes for Medical Research, Manhasset, New York; 6Geriatric Hospitalist Service, Northwell Health, Manhasset, New York; 7Medicine, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Hempstead, New York.

Disclosures

The authors have nothing to disclose.

Author and Disclosure Information

1Konar Professor of Geriatrics & Palliative Care, School of Medicine & Dentistry, University of Rochester, Rochester, New York; 2Geriatric Fracture Center, Highland Hospital, Rochester, New York; 3Orthopaedic Surgery, Brown University, Providence, Rhode Island; 4Trauma Orthopedics, Rhode Island Hospital, Providence, Rhode Island; 5Institute of Health Innovations & Outcomes Research, Feinstein Institutes for Medical Research, Manhasset, New York; 6Geriatric Hospitalist Service, Northwell Health, Manhasset, New York; 7Medicine, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Hempstead, New York.

Disclosures

The authors have nothing to disclose.

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We read with interest the article by Maxwell and Mirza.1 We appreciate using the large National Surgical Quality Improvement Project (NSQIP) database to assess comanagement outcomes, although we have concerns about the study design. Propensity score–matching (PSM) studies are limited; PSMs generate an average effect that neither establishes whether a treatment is optimal for a given patient nor control for unmeasured confounders.2 Some baseline characteristics suggest that the comanaged and noncomanaged populations are quite different and, therefore, likely had unmeasured confounders that contributed to not detecting true effects. Also, as suggested by the authors, the NSQIP definitions of comanagement and standardized hip fracture program are broad. Recent studies in hip fracture comanagement attribute best outcomes to an organized program, shared decision making, expert comanagers, and each service having full responsibility including writing their own orders.3-5 As no large database captures this distinction, it is not yet possible to perform a large, multicenter analysis. This type of comanagement cannot be studied in a randomized controlled trial. We recommend caution in overinterpreting the conclusions because there is substantial evidence in favor of optimized comanagement.

We read with interest the article by Maxwell and Mirza.1 We appreciate using the large National Surgical Quality Improvement Project (NSQIP) database to assess comanagement outcomes, although we have concerns about the study design. Propensity score–matching (PSM) studies are limited; PSMs generate an average effect that neither establishes whether a treatment is optimal for a given patient nor control for unmeasured confounders.2 Some baseline characteristics suggest that the comanaged and noncomanaged populations are quite different and, therefore, likely had unmeasured confounders that contributed to not detecting true effects. Also, as suggested by the authors, the NSQIP definitions of comanagement and standardized hip fracture program are broad. Recent studies in hip fracture comanagement attribute best outcomes to an organized program, shared decision making, expert comanagers, and each service having full responsibility including writing their own orders.3-5 As no large database captures this distinction, it is not yet possible to perform a large, multicenter analysis. This type of comanagement cannot be studied in a randomized controlled trial. We recommend caution in overinterpreting the conclusions because there is substantial evidence in favor of optimized comanagement.

References

1. Maxwell BG, Mirza A. Medical comanagement of hip fracture patients is not associated with superior perioperative outcomes: a propensity score-matched retrospective cohort analysis of the National Surgical Quality Improvement Project J Hosp Med. 2020;15:468-474. https://doi.org/10.12788/jhm.3343
2. Benedetto U, Head SJ, Angelini GD, Blackstone EH. Statistical primer: propensity score matching and its alternatives. Eur J Cardiothorac Surg. 2018;53(6):1112-1117. https://doi.org/10.1093/ejcts/ezy167
3. Friedman SM, Mendelson DA, Kates SL, McCann RM. Geriatric co-management of proximal femur fractures: total quality management and protocol-­driven care result in better outcomes for a frail patient population. J Am Geriatr Soc. 2008;56(7):1349-1356. https://doi.org/10.1111/j.1532-5415.2008.01770.x
4. Schnell S, Friedman SM, Mendelson DA, Bingham KW, Kates SL. The 1-year mortality of patients treated in a hip fracture program for elders. Geriatr Orthop Surg Rehabil. 2010;1(1):6-14. https://doi.org/10.1177/2151458510378105
5. Mendelson DA, Friedman SM. Principles of comanagement and the geriatric fracture center. Clin Geriatr Med. 2014;30(2):183-189. https://doi.org/10.1016/j.cger.2014.01.016

References

1. Maxwell BG, Mirza A. Medical comanagement of hip fracture patients is not associated with superior perioperative outcomes: a propensity score-matched retrospective cohort analysis of the National Surgical Quality Improvement Project J Hosp Med. 2020;15:468-474. https://doi.org/10.12788/jhm.3343
2. Benedetto U, Head SJ, Angelini GD, Blackstone EH. Statistical primer: propensity score matching and its alternatives. Eur J Cardiothorac Surg. 2018;53(6):1112-1117. https://doi.org/10.1093/ejcts/ezy167
3. Friedman SM, Mendelson DA, Kates SL, McCann RM. Geriatric co-management of proximal femur fractures: total quality management and protocol-­driven care result in better outcomes for a frail patient population. J Am Geriatr Soc. 2008;56(7):1349-1356. https://doi.org/10.1111/j.1532-5415.2008.01770.x
4. Schnell S, Friedman SM, Mendelson DA, Bingham KW, Kates SL. The 1-year mortality of patients treated in a hip fracture program for elders. Geriatr Orthop Surg Rehabil. 2010;1(1):6-14. https://doi.org/10.1177/2151458510378105
5. Mendelson DA, Friedman SM. Principles of comanagement and the geriatric fracture center. Clin Geriatr Med. 2014;30(2):183-189. https://doi.org/10.1016/j.cger.2014.01.016

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Daniel Ari Mendelson, MS, MD; Email: daniel_mendelson@urmc.rochester.edu; Telephone: 585-341-6776; Twitter: @DMendelsonMD.
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