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In the fall of 2015, the US Food and Drug Administration approved the addition of a novel, much-needed treatment option for patients with metastatic pancreatic cancer, a particularly hard-to-treat form of the disease, in the second-line setting following progression on gemcitabine- based chemotherapy.1 MM-398 is a modified version of the chemotherapeutic agent irinotecan, in which the drug is encapsulated in a nanoliposomal construct that is designed to improve delivery to the tumor and enhance anti-tumor efficacy while minimizing side effects in the rest of the body.

 

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Edited by Jame Abraham, MD; report prepared by Jane de Lartigue, PhD

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The Journal of Community and Supportive Oncology - 14(3)
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91-93
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irinotecan, pancreatic cancer, NAPOLI-1 trial, fluorouracil, leucovorin
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Author and Disclosure Information

Edited by Jame Abraham, MD; report prepared by Jane de Lartigue, PhD

Author and Disclosure Information

Edited by Jame Abraham, MD; report prepared by Jane de Lartigue, PhD

Article PDF
Article PDF

In the fall of 2015, the US Food and Drug Administration approved the addition of a novel, much-needed treatment option for patients with metastatic pancreatic cancer, a particularly hard-to-treat form of the disease, in the second-line setting following progression on gemcitabine- based chemotherapy.1 MM-398 is a modified version of the chemotherapeutic agent irinotecan, in which the drug is encapsulated in a nanoliposomal construct that is designed to improve delivery to the tumor and enhance anti-tumor efficacy while minimizing side effects in the rest of the body.

 

Click on the PDF icon at the top of this introduction to read the full article.

 

In the fall of 2015, the US Food and Drug Administration approved the addition of a novel, much-needed treatment option for patients with metastatic pancreatic cancer, a particularly hard-to-treat form of the disease, in the second-line setting following progression on gemcitabine- based chemotherapy.1 MM-398 is a modified version of the chemotherapeutic agent irinotecan, in which the drug is encapsulated in a nanoliposomal construct that is designed to improve delivery to the tumor and enhance anti-tumor efficacy while minimizing side effects in the rest of the body.

 

Click on the PDF icon at the top of this introduction to read the full article.

 

Issue
The Journal of Community and Supportive Oncology - 14(3)
Issue
The Journal of Community and Supportive Oncology - 14(3)
Page Number
91-93
Page Number
91-93
Publications
Publications
Topics
Article Type
Legacy Keywords
irinotecan, pancreatic cancer, NAPOLI-1 trial, fluorouracil, leucovorin
Legacy Keywords
irinotecan, pancreatic cancer, NAPOLI-1 trial, fluorouracil, leucovorin
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Citation Override
JCSO 2017;14(3):91-93
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