User login
Key clinical point: Fetal echocardiography can diagnose most major congenital heart diseases (CHD) with high accuracy. The accuracy can be affected by factors such as gestational age at diagnosis and double outlet right ventricle (DORV) diagnosis.
Major finding: Diagnostic accuracy rates were highest for univentricular hearts (97.6%; CI, 86.3%-99.9%), followed by tetralogy of Fallot (97.2%; CI 90.0%-99.2%) and transposition of the great arteries (96.2%; CI 89.2%-98.6%) and the lowest for heterotaxy syndrome (71.1%; CI 56.6%-82.2%). Factors such as a >25-week gestational age at diagnosis (adjusted risk ratio [aRR] 2.1; P = .023) and DORV diagnosis (aRR 8.33; P = .032) affected the diagnostic accuracy.
Study details: The data come from a retrospective, single-center study including 827 fetuses prenatally diagnosed with a major CHD that was confirmed for 589 either postnatally or via fetal autopsies.
Disclosures: This research was sponsored by the Stollery Children’s Hospital Foundation and Lois Hole Women’s Hospital/Royal Alexandra Hospital Foundation. The authors declared no conflicts of interest.
Source: Haberer K et al. Accuracy of fetal echocardiography in defining anatomical details: A single institutional experience over a 12-year period. J Am Soc Echocardiogr. 2022 (Mar 11). Doi: 10.1016/j.echo.2022.02.015
Key clinical point: Fetal echocardiography can diagnose most major congenital heart diseases (CHD) with high accuracy. The accuracy can be affected by factors such as gestational age at diagnosis and double outlet right ventricle (DORV) diagnosis.
Major finding: Diagnostic accuracy rates were highest for univentricular hearts (97.6%; CI, 86.3%-99.9%), followed by tetralogy of Fallot (97.2%; CI 90.0%-99.2%) and transposition of the great arteries (96.2%; CI 89.2%-98.6%) and the lowest for heterotaxy syndrome (71.1%; CI 56.6%-82.2%). Factors such as a >25-week gestational age at diagnosis (adjusted risk ratio [aRR] 2.1; P = .023) and DORV diagnosis (aRR 8.33; P = .032) affected the diagnostic accuracy.
Study details: The data come from a retrospective, single-center study including 827 fetuses prenatally diagnosed with a major CHD that was confirmed for 589 either postnatally or via fetal autopsies.
Disclosures: This research was sponsored by the Stollery Children’s Hospital Foundation and Lois Hole Women’s Hospital/Royal Alexandra Hospital Foundation. The authors declared no conflicts of interest.
Source: Haberer K et al. Accuracy of fetal echocardiography in defining anatomical details: A single institutional experience over a 12-year period. J Am Soc Echocardiogr. 2022 (Mar 11). Doi: 10.1016/j.echo.2022.02.015
Key clinical point: Fetal echocardiography can diagnose most major congenital heart diseases (CHD) with high accuracy. The accuracy can be affected by factors such as gestational age at diagnosis and double outlet right ventricle (DORV) diagnosis.
Major finding: Diagnostic accuracy rates were highest for univentricular hearts (97.6%; CI, 86.3%-99.9%), followed by tetralogy of Fallot (97.2%; CI 90.0%-99.2%) and transposition of the great arteries (96.2%; CI 89.2%-98.6%) and the lowest for heterotaxy syndrome (71.1%; CI 56.6%-82.2%). Factors such as a >25-week gestational age at diagnosis (adjusted risk ratio [aRR] 2.1; P = .023) and DORV diagnosis (aRR 8.33; P = .032) affected the diagnostic accuracy.
Study details: The data come from a retrospective, single-center study including 827 fetuses prenatally diagnosed with a major CHD that was confirmed for 589 either postnatally or via fetal autopsies.
Disclosures: This research was sponsored by the Stollery Children’s Hospital Foundation and Lois Hole Women’s Hospital/Royal Alexandra Hospital Foundation. The authors declared no conflicts of interest.
Source: Haberer K et al. Accuracy of fetal echocardiography in defining anatomical details: A single institutional experience over a 12-year period. J Am Soc Echocardiogr. 2022 (Mar 11). Doi: 10.1016/j.echo.2022.02.015