Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Virtual microscopy holds its own for prostate cancer histopathology

Publish date:: February 23, 2021

Key clinical point: Virtual microscopy was noninferior to standard light microscopy for the histopathological evaluation of prostate cancer.

Major finding: The agreement for Gleason grading score characteristics for primary and secondary patterns were similar with both methods, and virtual microscopy showed narrower limits of agreement than light microscopy, which suggests better repeatability.

Study details: The data come from a review by two uropathologists of 413 cores on 352 slides from 60 men with prostate cancer.

Disclosures: The study was supported by the Swedish Prostate Cancer Federation and the Swedish Cancer Society. The researchers had no financial conflicts to disclose.

Citation:

Zelic R et al. Sci Rep. 2021 Feb 5. doi: 10.1038/s41598-021-82911-z.

This Week's Must Reads

Consider potential cognitive complications prior to androgen deprivation therapy,

Diabetes raises risk of prostate cancer mortality in obese men,

Salivation inhibition fails to reduce radioiodine toxicity in prostate cancer,

Highest positive surgical margin predicts poor survival after prostatectomy,

Young minority men are underinformed about prostate cancer screening,

Must Reads in Prostate Cancer

Consider potential cognitive complications prior to androgen deprivation therapy,

Diabetes raises risk of prostate cancer mortality in obese men,

Salivation inhibition fails to reduce radioiodine toxicity in prostate cancer,

Highest positive surgical margin predicts poor survival after prostatectomy,

Young minority men are underinformed about prostate cancer screening,