Key clinical point: Cardiovascular risk factors (CVRF), such as current smoking status and diabetes mellitus, were associated with a decreased prevalence of migraine in middle-aged and older-aged women, whereas elevated diastolic blood pressure (BP) was associated with an increased prevalence.
Major findings: Among women, current smokers (odds ratio [OR] 0.72; 95% CI 0.58-0.90) and those with diabetes mellitus (OR 0.74; 95% CI 0.56-0.98) had a decreased prevalence of migraine. Conversely, women with elevated diastolic BP had an increased prevalence of migraine (OR per standard deviation increase 1.16; 95% CI 1.04-1.29). No significant association was observed between CVRF and migraine in men.
Study details: This cross-sectional analysis assessed sex-specific associations of CVRF with migraine in 7266 middle-aged and older participants (4181 women and 3085 men) from the Rotterdam Study .
Disclosures: The Rotterdam Study was funded by the Erasmus Medical Center, Erasmus University Rotterdam, and others . Antoinette MaassenVanDenBrink declared receiving research grants or consultation fees from various sources.
Source: Al-Hassany L, Acarsoy C, Ikram MK, et al. Sex-specific association of cardiovascular risk factors with migraine: The Population-Based Rotterdam Study. Neurology. 2024;103:e209700 (Aug 27). Doi: 10.1212/WNL.0000000000209700 Source