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Muscular Strength and Incidence of Type 2 Diabetes

Mayo Clin Proc; ePub 2019 Mar 11; Wang, et al

In a large cohort study of adult patients with no diabetes at baseline, a moderate level of muscular strength was associated with a lower risk of type 2 diabetes (T2D), independent of estimated cardiorespiratory fitness (CRF). A total of 4,681 adults aged 20‒100 years underwent muscular strength tests and maximal treadmill exercise tests between January 1, 1981, and December 31, 2006. Among the findings:

  • During a mean follow-up of 8.3 years, 229 of 4,681 participants (4.9%) had development of T2D.
  • Those with the middle level of muscular strength had a 32% lower risk of development of T2D compared with those with the lower level of muscular strength.
  • There was no significant association between the upper level of muscular strength and incident T2D.

Citation:

Wang Y, Lee D, Brellenthin AG, et al. Association of muscular strength and incidence of type 2 diabetes. [Published online ahead of print March 11, 2019]. Mayo Clin Proc. doi:10.1016/j.mayocp.2018.08.037.