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High-dose azithromycin or amoxicillin-clavulanate for recurrent otitis media?
PRACTICE RECOMMENDATIONS

Use high-dose azithromycin for 3 days if antibiotics are needed, instead of a 10-day course of high-dose amoxicillin-clavulanate for the treatment of recurrent or persistent acute otitis media. For every 10 children using azithromycin instead of amoxicillin-clavulanate, there is 1 additional clinical cure at 1 month and 1 less episode of diarrhea. However, no difference in clinical success is seen at 2 weeks.

 
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Practice Recommendations from Key Studies

Arrieta A, Arguedas A, Fernandez P, et al. High-dose azithromycin versus high-dose amoxicillin-clavulanate for treatment of children with recurrent or persistent acute otitis media. Antimicrob Agents Chemother 2003; 47:3179–3186.

Adrienne Z. Ables, PharmD
Petra K. Warren, MD
Spartanburg Family Medicine Residency Program, Spartanburg, SC. E-mail: aables@srhs.com.

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The Journal of Family Practice - 53(3)
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172-188
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Practice Recommendations from Key Studies

Arrieta A, Arguedas A, Fernandez P, et al. High-dose azithromycin versus high-dose amoxicillin-clavulanate for treatment of children with recurrent or persistent acute otitis media. Antimicrob Agents Chemother 2003; 47:3179–3186.

Adrienne Z. Ables, PharmD
Petra K. Warren, MD
Spartanburg Family Medicine Residency Program, Spartanburg, SC. E-mail: aables@srhs.com.

Author and Disclosure Information

Practice Recommendations from Key Studies

Arrieta A, Arguedas A, Fernandez P, et al. High-dose azithromycin versus high-dose amoxicillin-clavulanate for treatment of children with recurrent or persistent acute otitis media. Antimicrob Agents Chemother 2003; 47:3179–3186.

Adrienne Z. Ables, PharmD
Petra K. Warren, MD
Spartanburg Family Medicine Residency Program, Spartanburg, SC. E-mail: aables@srhs.com.

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PRACTICE RECOMMENDATIONS

Use high-dose azithromycin for 3 days if antibiotics are needed, instead of a 10-day course of high-dose amoxicillin-clavulanate for the treatment of recurrent or persistent acute otitis media. For every 10 children using azithromycin instead of amoxicillin-clavulanate, there is 1 additional clinical cure at 1 month and 1 less episode of diarrhea. However, no difference in clinical success is seen at 2 weeks.

 
PRACTICE RECOMMENDATIONS

Use high-dose azithromycin for 3 days if antibiotics are needed, instead of a 10-day course of high-dose amoxicillin-clavulanate for the treatment of recurrent or persistent acute otitis media. For every 10 children using azithromycin instead of amoxicillin-clavulanate, there is 1 additional clinical cure at 1 month and 1 less episode of diarrhea. However, no difference in clinical success is seen at 2 weeks.

 
Issue
The Journal of Family Practice - 53(3)
Issue
The Journal of Family Practice - 53(3)
Page Number
172-188
Page Number
172-188
Publications
Publications
Topics
Article Type
Display Headline
High-dose azithromycin or amoxicillin-clavulanate for recurrent otitis media?
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High-dose azithromycin or amoxicillin-clavulanate for recurrent otitis media?
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