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Elevated BP in Young Adults & Subsequent CVD Risk

JAMA; 2018 Nov 6; Yano, Reis, et al

Young adults with elevated blood pressure (BP), stage 1 hypertension, and stage 2 hypertension before age 40 years, as defined by the BP classification in the 2017 American College of Cardiology/American Heart Association (ACC/AHA) guidelines, had significantly higher risk for subsequent cardiovascular disease (CVD) events compared to those with normal BP before age 40, a new study found. The prospective cohort study included 4,851 young adults (aged 18‒30 years) with CVD events as the primary outcome. Researchers found:

  • Over a median follow-up of 18.8 years, 228 incident CVD events occurred.
  • CVD incidence rates for normal BP, elevated BP, stage 1 hypertension, and stage 2 hypertension were 1.37, 2.74, 3.15, and 8.04 per 1,000 person-years, respectively.
  • After multivariable adjustment, hazard ratios (HRs) for CVD events for elevated BP, stage 1 hypertension, and stage 2 hypertension vs normal BP were 1.67, 1.75, and 3.49, respectively.

Citation:

Yano Y, Reis JP, Colangelo LA, et al. Association of blood pressure classification in young adults using the 2017 American College of Cardiology/American Heart Association Blood Pressure Guideline with cardiovascular events later in life. JAMA. 2018;320(17):1774–1782. doi:10.1001/jama.2018.13551.