App tied to reducing insomnia, depression in adults

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ROCKVILLE, MD. – Using a digital application could allow more adults to try cognitive-behavioral therapy (CBT) to combat insomnia and expand access to a technique that’s been shown to ward off depression, a researcher said at a National Institute of Mental Health conference on mental health services research.

Dr. Philip C. Cheng


Previous research has shown that CBT for insomnia (CBT-I) that’s conducted in person is not only effective for insomnia but also can reduce co-occurring depression. In fact, the treatment effects for depression are roughly the same magnitude as antidepressants but with fewer side effects and contraindications, said Philip C. Cheng, PhD, of the Sleep Disorders & Research Center at the Henry Ford Health System in Detroit. He cited a systematic literature review published recently that found CBT-I to be a promising treatment for depression comorbid with insomnia (J Psychosom Res. 2018 Mar;106:1-2).

“We’ve got a two-birds-with-one-stone kind of a deal,” Dr. Cheng said, referring to the ability of CBT-I to address both disorders. “It’s hard to resist the impulse to say: ‘This is great. Let’s get this out to everyone who has insomnia.’ ”

But there’s only a limited pool of about 1,200 health care professionals experienced in CBT-I to serve a much larger pool of people who might need help warding off depression, he said. The NIMH estimates that 16.2 million adults in the United States had at least one major depressive episode in 2016, which is about 6.7% of all U.S. adults. To address the shortage, developers have created digital apps such as Sleepio, which Dr. Cheng and his colleagues used in their research.

For this study, they recruited people with insomnia who did not at the time have depression. Patients were assigned to either use the Sleepio app or follow a more traditional sleep education program. The latter consisted of six weekly emails with tips on sleep hygiene, Dr. Cheng said. These contained the typical messages that a patient would receive from a physician to address a sleep disorder, he added.

“The doctor says: ‘Don’t drink caffeine; make sure you sleep in a dark room,’ things like that,” Dr. Cheng said. “A lot of evidence has shown that this is not an effective stand-alone treatment for insomnia.”

With Sleepio, users get online assistance in addressing their challenges with sleep. Dr. Cheng said he and his colleagues used Sleepio because of its grounding in CBT methods. Other apps built with the same commitment to CBT might deliver similar results, according to Dr. Cheng. He presented the results seen in 166 people who used the digital CBT-I approach and 146 who received sleep education.

An interim analysis of results showed that within a period of 12 months after treatment, 20% of those in the sleep education control group developed incident depression, whereas only 10% of those in the CBT-I did, Dr. Cheng said. Analyzing the results, Dr. Cheng and his colleagues said those numbers indicate that the number needed to treat to prevent one case of depression was 10.

The subscription for this online tool costs about $400 a year, so it would cost $4,000 to prevent one case of depression, Dr. Cheng said.

Sleepio, also available on web-based platforms, is compatible with personal tracking devices, such as Fitbit. Sleepio users also have online community members who can share their experiences and support (Cogn Behav Pract. 2018 Aug;25[3]:442-8). It was created by Colin Espie, PhD, DSc, of the University of Oxford (England) and Peter Hames. Dr. Espie and Mr. Hames are cofounders of Big Health, a company that creates automated behavioral programs.

The Robert Wood Johnson Foundation funded the study. Dr. Cheng also is funded by a National Institutes of Health grant (K23HL138166). Sleepio provided its product for the study free of charge. Dr. Cheng said that he has no relevant conflicts of interest and that he has funding from Harmony Biosciences for a study unrelated to this work.

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ROCKVILLE, MD. – Using a digital application could allow more adults to try cognitive-behavioral therapy (CBT) to combat insomnia and expand access to a technique that’s been shown to ward off depression, a researcher said at a National Institute of Mental Health conference on mental health services research.

Dr. Philip C. Cheng


Previous research has shown that CBT for insomnia (CBT-I) that’s conducted in person is not only effective for insomnia but also can reduce co-occurring depression. In fact, the treatment effects for depression are roughly the same magnitude as antidepressants but with fewer side effects and contraindications, said Philip C. Cheng, PhD, of the Sleep Disorders & Research Center at the Henry Ford Health System in Detroit. He cited a systematic literature review published recently that found CBT-I to be a promising treatment for depression comorbid with insomnia (J Psychosom Res. 2018 Mar;106:1-2).

“We’ve got a two-birds-with-one-stone kind of a deal,” Dr. Cheng said, referring to the ability of CBT-I to address both disorders. “It’s hard to resist the impulse to say: ‘This is great. Let’s get this out to everyone who has insomnia.’ ”

But there’s only a limited pool of about 1,200 health care professionals experienced in CBT-I to serve a much larger pool of people who might need help warding off depression, he said. The NIMH estimates that 16.2 million adults in the United States had at least one major depressive episode in 2016, which is about 6.7% of all U.S. adults. To address the shortage, developers have created digital apps such as Sleepio, which Dr. Cheng and his colleagues used in their research.

For this study, they recruited people with insomnia who did not at the time have depression. Patients were assigned to either use the Sleepio app or follow a more traditional sleep education program. The latter consisted of six weekly emails with tips on sleep hygiene, Dr. Cheng said. These contained the typical messages that a patient would receive from a physician to address a sleep disorder, he added.

“The doctor says: ‘Don’t drink caffeine; make sure you sleep in a dark room,’ things like that,” Dr. Cheng said. “A lot of evidence has shown that this is not an effective stand-alone treatment for insomnia.”

With Sleepio, users get online assistance in addressing their challenges with sleep. Dr. Cheng said he and his colleagues used Sleepio because of its grounding in CBT methods. Other apps built with the same commitment to CBT might deliver similar results, according to Dr. Cheng. He presented the results seen in 166 people who used the digital CBT-I approach and 146 who received sleep education.

An interim analysis of results showed that within a period of 12 months after treatment, 20% of those in the sleep education control group developed incident depression, whereas only 10% of those in the CBT-I did, Dr. Cheng said. Analyzing the results, Dr. Cheng and his colleagues said those numbers indicate that the number needed to treat to prevent one case of depression was 10.

The subscription for this online tool costs about $400 a year, so it would cost $4,000 to prevent one case of depression, Dr. Cheng said.

Sleepio, also available on web-based platforms, is compatible with personal tracking devices, such as Fitbit. Sleepio users also have online community members who can share their experiences and support (Cogn Behav Pract. 2018 Aug;25[3]:442-8). It was created by Colin Espie, PhD, DSc, of the University of Oxford (England) and Peter Hames. Dr. Espie and Mr. Hames are cofounders of Big Health, a company that creates automated behavioral programs.

The Robert Wood Johnson Foundation funded the study. Dr. Cheng also is funded by a National Institutes of Health grant (K23HL138166). Sleepio provided its product for the study free of charge. Dr. Cheng said that he has no relevant conflicts of interest and that he has funding from Harmony Biosciences for a study unrelated to this work.

 

ROCKVILLE, MD. – Using a digital application could allow more adults to try cognitive-behavioral therapy (CBT) to combat insomnia and expand access to a technique that’s been shown to ward off depression, a researcher said at a National Institute of Mental Health conference on mental health services research.

Dr. Philip C. Cheng


Previous research has shown that CBT for insomnia (CBT-I) that’s conducted in person is not only effective for insomnia but also can reduce co-occurring depression. In fact, the treatment effects for depression are roughly the same magnitude as antidepressants but with fewer side effects and contraindications, said Philip C. Cheng, PhD, of the Sleep Disorders & Research Center at the Henry Ford Health System in Detroit. He cited a systematic literature review published recently that found CBT-I to be a promising treatment for depression comorbid with insomnia (J Psychosom Res. 2018 Mar;106:1-2).

“We’ve got a two-birds-with-one-stone kind of a deal,” Dr. Cheng said, referring to the ability of CBT-I to address both disorders. “It’s hard to resist the impulse to say: ‘This is great. Let’s get this out to everyone who has insomnia.’ ”

But there’s only a limited pool of about 1,200 health care professionals experienced in CBT-I to serve a much larger pool of people who might need help warding off depression, he said. The NIMH estimates that 16.2 million adults in the United States had at least one major depressive episode in 2016, which is about 6.7% of all U.S. adults. To address the shortage, developers have created digital apps such as Sleepio, which Dr. Cheng and his colleagues used in their research.

For this study, they recruited people with insomnia who did not at the time have depression. Patients were assigned to either use the Sleepio app or follow a more traditional sleep education program. The latter consisted of six weekly emails with tips on sleep hygiene, Dr. Cheng said. These contained the typical messages that a patient would receive from a physician to address a sleep disorder, he added.

“The doctor says: ‘Don’t drink caffeine; make sure you sleep in a dark room,’ things like that,” Dr. Cheng said. “A lot of evidence has shown that this is not an effective stand-alone treatment for insomnia.”

With Sleepio, users get online assistance in addressing their challenges with sleep. Dr. Cheng said he and his colleagues used Sleepio because of its grounding in CBT methods. Other apps built with the same commitment to CBT might deliver similar results, according to Dr. Cheng. He presented the results seen in 166 people who used the digital CBT-I approach and 146 who received sleep education.

An interim analysis of results showed that within a period of 12 months after treatment, 20% of those in the sleep education control group developed incident depression, whereas only 10% of those in the CBT-I did, Dr. Cheng said. Analyzing the results, Dr. Cheng and his colleagues said those numbers indicate that the number needed to treat to prevent one case of depression was 10.

The subscription for this online tool costs about $400 a year, so it would cost $4,000 to prevent one case of depression, Dr. Cheng said.

Sleepio, also available on web-based platforms, is compatible with personal tracking devices, such as Fitbit. Sleepio users also have online community members who can share their experiences and support (Cogn Behav Pract. 2018 Aug;25[3]:442-8). It was created by Colin Espie, PhD, DSc, of the University of Oxford (England) and Peter Hames. Dr. Espie and Mr. Hames are cofounders of Big Health, a company that creates automated behavioral programs.

The Robert Wood Johnson Foundation funded the study. Dr. Cheng also is funded by a National Institutes of Health grant (K23HL138166). Sleepio provided its product for the study free of charge. Dr. Cheng said that he has no relevant conflicts of interest and that he has funding from Harmony Biosciences for a study unrelated to this work.

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Key clinical point: The number needed to prevent one case of depression using the app is estimated to be 10.

Major finding: Within a period of 12 months after treatment, 20% of those in the sleep education control group developed incident depression, whereas only 10% of those in the CBT-I group did.

Study details: An interim analysis of results for 312 patients.

Disclosures: The Robert Wood Johnson Foundation funded the study. Dr. Cheng also is funded by a National Institutes of Health grant (K23HL138166). Sleepio provided its product for the study free of charge. Dr. Cheng said that he has no relevant conflicts of interest and that he receives funding from Harmony Biosciences for a study unrelated to this work.
 

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Address physical health risks of people with SMI

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ROCKVILLE, MD. – The problem of medical comorbidities in people with serious mental illness (SMI) persists and must be addressed, researchers said at a National Institute on Mental Health conference on mental health services research. Part of that effort, they said, is a more careful consideration of risks tied to the off-label use of second-generation antipsychotics.

Dr. Joshua Breslau of the Rand Corporation
Courtesy Dr. Joshua Breslau
Dr. Joshua Breslau


The researchers discussed strategies aimed at combating obesity and diabetes, as well as behaviors such as smoking and sedentary lifestyle.

“One of the things that jumps out is the tremendous need for evidence-based strategies to address these physical health problems that are common in general population but even more of a burden for people with serious mental illness,” said Susan T. Azrin, PhD, of the NIMH, in an interview.

A study published in 2015, estimated that people with schizophrenia, for example, might lose almost 30 years of life because of premature death. Individuals with serious mental illness also experience elevated morbidity from cardiovascular disease and cancer. The NIMH and other federal agencies have in recent years looked for ways to help people with SMI quit smoking, and better control their weight and cholesterol.

But approaches that sound promising for boosting physical fitness in this group of patients have not always proven successful. Joshua Breslau, PhD, ScD, of the Rand Corp. discussed findings from a 2014 paper where he and his colleagues reported somewhat disappointing results from a study of federal Primary and Behavioral Health Care Integration grants.

The researchers matched clinics receiving this funding with similar ones that did not. They found that people with mental illness treated at the clinics receiving the grants showed improvements in some indicators of physical health (diastolic blood pressure, total cholesterol, LDL cholesterol, and fasting plasma glucose) but not in others (systolic blood pressure, body mass index, HDL cholesterol, hemoglobin A1c, triglycerides, self-reported smoking). Dr. Breslau said he and his colleagues also found only limited benefits in quality of care for physical health conditions associated with the grant program. Still, he remains hopeful.

“There is some potential here,” Dr. Breslau said. “Sometimes, we are seeing positive effects, but it’s certainly not a slam-dunk.”

He noted that opening a new setting for primary care services could strain a workforce that’s already in short supply. In addition, he said, attempts to fold primary care services into mental health programs could, in some cases, result in replication of care of chronic conditions for certain patients with SMI.

We “may still not reach that portion of the target population that has the greatest need,” Dr. Breslau said in an interview. “The new services may turn out to be duplicative rather than filling a gap.”

In another session, Gail L. Daumit, MD, MHS, of Johns Hopkins University, Baltimore, discussed her plan to build on a past success in helping people with SMI lose weight.

In the ACHIEVE (Achieving Healthy Lifestyles In Psych Rehabilitation) trial, Dr. Daumit and her colleagues found that people enrolled in an intervention group lost an average of 3.2 kg more than did a control group after 18 months (N Engl J Med. 2013;368:1594-602). The intervention steps included alternating group and individual weight management sessions, on-site group physical activity three times weekly, and weigh-ins. The study had 291 patients who were randomized between the control and intervention groups.

Dr. Daumit said she intends to adapt the weight loss intervention approach tested in the ACHIEVE trial to a more portable method of intervention that can be used more broadly. She’s seeking to scale up effective interventions to address cardiovascular risk factors in people with SMI.

“Our goal is not just to get process-of-care measures like ‘counseling was delivered,’ ‘a medicine was started,’ but to actually show impact on health outcomes,” Dr. Daumit said.
 

 

 

Risks tied to antipsychotics

People with SMI face cardiovascular risks not only from unhealthy behaviors but also from the medications used to treat their psychiatric conditions. The American Diabetes Association and American Psychiatric Association in 2004 released a consensus statement on the impact of antipsychotics such as clozapine, olanzapine, and risperidone on obesity and diabetes. It included guidelines for monitoring the metabolic status of patients both at baseline and after initiating treatment, including checking body mass index, waist circumference, blood pressure, fasting glucose, and fasting lipids.

Yet, substantial evidence suggests that the medical community still has not paid enough attention to the health risks of those medications, said Alisa Busch, MD, of Harvard Medical School, Boston.

“A slew of research has shown since then that we have done a very poor job in adhering to those monitoring guidelines,” Dr. Busch said.



A fellow panelist, Marcela Horvitz-Lennon, MD, MPH, of the Rand Corp., presented results from her study showing continued common use of second-generation antipsychotics for off-label use for treatment of anxiety, posttraumatic stress disorder, and dementia in people of all ages.

Consistent with previous research, Dr. Horvitz-Lennon and her colleagues found that off-label use of second-generation antipsychotics was common during 2008-2012 in the four states they studied. They looked at available data from fee-for-service Medicare, Medicaid, and dually (Medicaid-Medicare) covered adult beneficiaries in California, Georgia, Mississippi, and Oklahoma.

Throughout the study period, California had the highest rate of fee-for-service beneficiaries whose SGA use was consistently off label (44.6%). Georgia had the lowest rate of always off-label use (35.1%), while Mississippi (42%) and Oklahoma (36.3%) fell somewhere in the middle.

When second-generation antipsychotics have approved uses such as schizophrenia, the known profile of a medication gives some assurance that the benefit of the medications will exceed the risk for that patient, she said. “When the medication is used off label, the implication is that there is no good evidence that the benefits are there,” Dr. Horvitz-Lennon said. “Hence, the potential for harm is most likely exceeding that likely or unlikely benefit.”

Dr. Daumit, Dr. Breslau, and Dr. Horvitz-Lennon said they had no financial disclosures.

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ROCKVILLE, MD. – The problem of medical comorbidities in people with serious mental illness (SMI) persists and must be addressed, researchers said at a National Institute on Mental Health conference on mental health services research. Part of that effort, they said, is a more careful consideration of risks tied to the off-label use of second-generation antipsychotics.

Dr. Joshua Breslau of the Rand Corporation
Courtesy Dr. Joshua Breslau
Dr. Joshua Breslau


The researchers discussed strategies aimed at combating obesity and diabetes, as well as behaviors such as smoking and sedentary lifestyle.

“One of the things that jumps out is the tremendous need for evidence-based strategies to address these physical health problems that are common in general population but even more of a burden for people with serious mental illness,” said Susan T. Azrin, PhD, of the NIMH, in an interview.

A study published in 2015, estimated that people with schizophrenia, for example, might lose almost 30 years of life because of premature death. Individuals with serious mental illness also experience elevated morbidity from cardiovascular disease and cancer. The NIMH and other federal agencies have in recent years looked for ways to help people with SMI quit smoking, and better control their weight and cholesterol.

But approaches that sound promising for boosting physical fitness in this group of patients have not always proven successful. Joshua Breslau, PhD, ScD, of the Rand Corp. discussed findings from a 2014 paper where he and his colleagues reported somewhat disappointing results from a study of federal Primary and Behavioral Health Care Integration grants.

The researchers matched clinics receiving this funding with similar ones that did not. They found that people with mental illness treated at the clinics receiving the grants showed improvements in some indicators of physical health (diastolic blood pressure, total cholesterol, LDL cholesterol, and fasting plasma glucose) but not in others (systolic blood pressure, body mass index, HDL cholesterol, hemoglobin A1c, triglycerides, self-reported smoking). Dr. Breslau said he and his colleagues also found only limited benefits in quality of care for physical health conditions associated with the grant program. Still, he remains hopeful.

“There is some potential here,” Dr. Breslau said. “Sometimes, we are seeing positive effects, but it’s certainly not a slam-dunk.”

He noted that opening a new setting for primary care services could strain a workforce that’s already in short supply. In addition, he said, attempts to fold primary care services into mental health programs could, in some cases, result in replication of care of chronic conditions for certain patients with SMI.

We “may still not reach that portion of the target population that has the greatest need,” Dr. Breslau said in an interview. “The new services may turn out to be duplicative rather than filling a gap.”

In another session, Gail L. Daumit, MD, MHS, of Johns Hopkins University, Baltimore, discussed her plan to build on a past success in helping people with SMI lose weight.

In the ACHIEVE (Achieving Healthy Lifestyles In Psych Rehabilitation) trial, Dr. Daumit and her colleagues found that people enrolled in an intervention group lost an average of 3.2 kg more than did a control group after 18 months (N Engl J Med. 2013;368:1594-602). The intervention steps included alternating group and individual weight management sessions, on-site group physical activity three times weekly, and weigh-ins. The study had 291 patients who were randomized between the control and intervention groups.

Dr. Daumit said she intends to adapt the weight loss intervention approach tested in the ACHIEVE trial to a more portable method of intervention that can be used more broadly. She’s seeking to scale up effective interventions to address cardiovascular risk factors in people with SMI.

“Our goal is not just to get process-of-care measures like ‘counseling was delivered,’ ‘a medicine was started,’ but to actually show impact on health outcomes,” Dr. Daumit said.
 

 

 

Risks tied to antipsychotics

People with SMI face cardiovascular risks not only from unhealthy behaviors but also from the medications used to treat their psychiatric conditions. The American Diabetes Association and American Psychiatric Association in 2004 released a consensus statement on the impact of antipsychotics such as clozapine, olanzapine, and risperidone on obesity and diabetes. It included guidelines for monitoring the metabolic status of patients both at baseline and after initiating treatment, including checking body mass index, waist circumference, blood pressure, fasting glucose, and fasting lipids.

Yet, substantial evidence suggests that the medical community still has not paid enough attention to the health risks of those medications, said Alisa Busch, MD, of Harvard Medical School, Boston.

“A slew of research has shown since then that we have done a very poor job in adhering to those monitoring guidelines,” Dr. Busch said.



A fellow panelist, Marcela Horvitz-Lennon, MD, MPH, of the Rand Corp., presented results from her study showing continued common use of second-generation antipsychotics for off-label use for treatment of anxiety, posttraumatic stress disorder, and dementia in people of all ages.

Consistent with previous research, Dr. Horvitz-Lennon and her colleagues found that off-label use of second-generation antipsychotics was common during 2008-2012 in the four states they studied. They looked at available data from fee-for-service Medicare, Medicaid, and dually (Medicaid-Medicare) covered adult beneficiaries in California, Georgia, Mississippi, and Oklahoma.

Throughout the study period, California had the highest rate of fee-for-service beneficiaries whose SGA use was consistently off label (44.6%). Georgia had the lowest rate of always off-label use (35.1%), while Mississippi (42%) and Oklahoma (36.3%) fell somewhere in the middle.

When second-generation antipsychotics have approved uses such as schizophrenia, the known profile of a medication gives some assurance that the benefit of the medications will exceed the risk for that patient, she said. “When the medication is used off label, the implication is that there is no good evidence that the benefits are there,” Dr. Horvitz-Lennon said. “Hence, the potential for harm is most likely exceeding that likely or unlikely benefit.”

Dr. Daumit, Dr. Breslau, and Dr. Horvitz-Lennon said they had no financial disclosures.

 

ROCKVILLE, MD. – The problem of medical comorbidities in people with serious mental illness (SMI) persists and must be addressed, researchers said at a National Institute on Mental Health conference on mental health services research. Part of that effort, they said, is a more careful consideration of risks tied to the off-label use of second-generation antipsychotics.

Dr. Joshua Breslau of the Rand Corporation
Courtesy Dr. Joshua Breslau
Dr. Joshua Breslau


The researchers discussed strategies aimed at combating obesity and diabetes, as well as behaviors such as smoking and sedentary lifestyle.

“One of the things that jumps out is the tremendous need for evidence-based strategies to address these physical health problems that are common in general population but even more of a burden for people with serious mental illness,” said Susan T. Azrin, PhD, of the NIMH, in an interview.

A study published in 2015, estimated that people with schizophrenia, for example, might lose almost 30 years of life because of premature death. Individuals with serious mental illness also experience elevated morbidity from cardiovascular disease and cancer. The NIMH and other federal agencies have in recent years looked for ways to help people with SMI quit smoking, and better control their weight and cholesterol.

But approaches that sound promising for boosting physical fitness in this group of patients have not always proven successful. Joshua Breslau, PhD, ScD, of the Rand Corp. discussed findings from a 2014 paper where he and his colleagues reported somewhat disappointing results from a study of federal Primary and Behavioral Health Care Integration grants.

The researchers matched clinics receiving this funding with similar ones that did not. They found that people with mental illness treated at the clinics receiving the grants showed improvements in some indicators of physical health (diastolic blood pressure, total cholesterol, LDL cholesterol, and fasting plasma glucose) but not in others (systolic blood pressure, body mass index, HDL cholesterol, hemoglobin A1c, triglycerides, self-reported smoking). Dr. Breslau said he and his colleagues also found only limited benefits in quality of care for physical health conditions associated with the grant program. Still, he remains hopeful.

“There is some potential here,” Dr. Breslau said. “Sometimes, we are seeing positive effects, but it’s certainly not a slam-dunk.”

He noted that opening a new setting for primary care services could strain a workforce that’s already in short supply. In addition, he said, attempts to fold primary care services into mental health programs could, in some cases, result in replication of care of chronic conditions for certain patients with SMI.

We “may still not reach that portion of the target population that has the greatest need,” Dr. Breslau said in an interview. “The new services may turn out to be duplicative rather than filling a gap.”

In another session, Gail L. Daumit, MD, MHS, of Johns Hopkins University, Baltimore, discussed her plan to build on a past success in helping people with SMI lose weight.

In the ACHIEVE (Achieving Healthy Lifestyles In Psych Rehabilitation) trial, Dr. Daumit and her colleagues found that people enrolled in an intervention group lost an average of 3.2 kg more than did a control group after 18 months (N Engl J Med. 2013;368:1594-602). The intervention steps included alternating group and individual weight management sessions, on-site group physical activity three times weekly, and weigh-ins. The study had 291 patients who were randomized between the control and intervention groups.

Dr. Daumit said she intends to adapt the weight loss intervention approach tested in the ACHIEVE trial to a more portable method of intervention that can be used more broadly. She’s seeking to scale up effective interventions to address cardiovascular risk factors in people with SMI.

“Our goal is not just to get process-of-care measures like ‘counseling was delivered,’ ‘a medicine was started,’ but to actually show impact on health outcomes,” Dr. Daumit said.
 

 

 

Risks tied to antipsychotics

People with SMI face cardiovascular risks not only from unhealthy behaviors but also from the medications used to treat their psychiatric conditions. The American Diabetes Association and American Psychiatric Association in 2004 released a consensus statement on the impact of antipsychotics such as clozapine, olanzapine, and risperidone on obesity and diabetes. It included guidelines for monitoring the metabolic status of patients both at baseline and after initiating treatment, including checking body mass index, waist circumference, blood pressure, fasting glucose, and fasting lipids.

Yet, substantial evidence suggests that the medical community still has not paid enough attention to the health risks of those medications, said Alisa Busch, MD, of Harvard Medical School, Boston.

“A slew of research has shown since then that we have done a very poor job in adhering to those monitoring guidelines,” Dr. Busch said.



A fellow panelist, Marcela Horvitz-Lennon, MD, MPH, of the Rand Corp., presented results from her study showing continued common use of second-generation antipsychotics for off-label use for treatment of anxiety, posttraumatic stress disorder, and dementia in people of all ages.

Consistent with previous research, Dr. Horvitz-Lennon and her colleagues found that off-label use of second-generation antipsychotics was common during 2008-2012 in the four states they studied. They looked at available data from fee-for-service Medicare, Medicaid, and dually (Medicaid-Medicare) covered adult beneficiaries in California, Georgia, Mississippi, and Oklahoma.

Throughout the study period, California had the highest rate of fee-for-service beneficiaries whose SGA use was consistently off label (44.6%). Georgia had the lowest rate of always off-label use (35.1%), while Mississippi (42%) and Oklahoma (36.3%) fell somewhere in the middle.

When second-generation antipsychotics have approved uses such as schizophrenia, the known profile of a medication gives some assurance that the benefit of the medications will exceed the risk for that patient, she said. “When the medication is used off label, the implication is that there is no good evidence that the benefits are there,” Dr. Horvitz-Lennon said. “Hence, the potential for harm is most likely exceeding that likely or unlikely benefit.”

Dr. Daumit, Dr. Breslau, and Dr. Horvitz-Lennon said they had no financial disclosures.

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For people with SMI, disclosure still challenging

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– People working in the mental health field are more likely to disclose their past or present treatment for psychosis than are professionals in other fields, a researcher said at a National Institute of Mental Health conference on mental health services research.

The researcher, Nev Jones, PhD, presented the findings of a small survey she conducted in 2014 and 2015 of adults with current or past experiences of psychotic disorder who described themselves as having had or having a successful career. The research was not conducted for publication purposes but as part of an effort to develop tools for students with psychosis as they continued in higher education, said Dr. Jones, of the department of mental health law and policy at the University of South Florida, Tampa.

One of those tools was a closed program that was akin to Facebook; people with early psychosis could use this to “look at successful adults across a wide range of careers and how they had navigated accommodations, disclosure, education as well as vocational choice,” she said.

Dr. Jones did not ask participants about their gender and race, but she did query them on highest degree earned. The poll was disseminated with the assistance of the National Alliance on Mental Illness and that of Stanford (Calif.) University, where Dr. Jones was a postdoctoral fellow. Of the sample presented, 33% had a masters degree (MSW, MBA), and 15% had a doctoral level degree (JD, MD, PhD).

People who worked in fields outside of mental health care were far less likely to have revealed their conditions to colleagues or employers, with 14 of 67 participants having made no disclosure. Of 14 who had made no disclosure, 12 were in fields such as banking, economics, secondary education, nursing, pediatrics, and computer programming.

Dr. Jones said she received several calls from students and staff at Stanford who were unwilling to fill out the survey.

“They were very concerned about the risks of inadvertent disclosure, even though it was anonymous, because they had unique, potentially identifiable career paths that they could not lay out in their responses without the fear that that would disclose [identify] them,” Dr. Jones said.

An additional 17 of the 67 participants made what Dr. Jones termed “selective disclosures,” such as telling a coworker who was considered a friend or a supportive boss. The majority of the respondents to Jones’s survey – 36 of the 67 participants – were open about their conditions. All but one of the respondents in this broad-disclosure group worked in mental health fields.

Dr. Jones described the broad-disclosure designation as “meaning that there is nobody in their life who doesn’t know.”

“They’re out professionally. They’ve published a book. They speak,” Dr. Jones said. “If you Google them on the Internet, you would quickly learn that they had a psychiatric disability or psychosis.”

Dr. Jones herself falls into that camp. She’s told media outlets, including the online newspaper MinnPost, about her own experience being diagnosed with schizophrenia while a PhD student. The online magazine Pacific Standard ran a full-length feature about her return to academia.

 

 


About 100,000 adolescents and young adults in the United States experience first-episode psychosis each year, and the peak onset hits between 15 and 25 years of age, according to the NIMH. About a decade ago, the NIMH launched its Recovery After an Initial Schizophrenia Episode (RAISE) initiative to examine use of coordinated specialty care treatments for people who were experiencing a first episode of psychosis. Congress in 2014 moved to provide a stream of federal funding for those kinds of efforts.

“We’re going to be soon starting to discharge, on an annual basis, potentially tens of thousands of young people from these specialized early intervention programs,” Dr. Jones said. “So it becomes really pressing to understand what’s happening to them in the context of reintegration.”

Another presenter at the panel, Marjorie L. Baldwin, PhD, of Arizona State University, Tempe, is an economist who has published a book based, in part, on her son’s struggles, “Beyond Schizophrenia: Living and Working With a Serious Mental Illness” (Lanham, Md.: Rowman & Littlefield Publishers, 2016).

She presented findings from a pilot study for a larger project looking at the issue of disclosures of serious mental illness in the workplace. She and her colleague in this work, Steven C. Marcus, PhD, of the University of Pennsylvania, Philadelphia, separately spoke about the difficulties in securing funding for the project, including five failed R01 grant applications.

“The 6th time was the charm with NIH,” Dr. Baldwin said.

An initial hurdle was finding a cost-effective way to identify workers with serious mental illness who hold or have held what she termed “competitive jobs,” which Dr. Baldwin described as those that paid at least minimum wage and are not subsidized for people with disabilities.

“You cannot do this kind of a study with random dialing because it would be way too expensive,” she said. “Schizophrenia and serious mental illnesses are not rare, but they are fairly uncommon.”

Several years ago, though, she learned of a long-running health survey into which she could “piggyback” questions on mental health status. She presented results of a pilot study with about 230 people with serious mental illness who had held or had competitive jobs. Of this group, 52% had left their most recent job for reasons other than mental illness, while those conditions had caused an additional 21% to leave. But Dr. Baldwin and her colleagues found 27% still working.

Like Dr. Jones, Dr. Baldwin said some of those workers were in professional fields, such as accounting, law, education; others worked in the service and construction industries.

“Contrary to the stereotypes, people with serious mental illness whose symptoms are reasonably well controlled can work, and many are capable of supporting themselves in mainstream competitive jobs,” Dr. Baldwin said.

Dr. Jones had no disclosures tied to her survey. Dr. Baldwin and Dr. Marcus had no disclosures other than the NIH R01 grant.

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– People working in the mental health field are more likely to disclose their past or present treatment for psychosis than are professionals in other fields, a researcher said at a National Institute of Mental Health conference on mental health services research.

The researcher, Nev Jones, PhD, presented the findings of a small survey she conducted in 2014 and 2015 of adults with current or past experiences of psychotic disorder who described themselves as having had or having a successful career. The research was not conducted for publication purposes but as part of an effort to develop tools for students with psychosis as they continued in higher education, said Dr. Jones, of the department of mental health law and policy at the University of South Florida, Tampa.

One of those tools was a closed program that was akin to Facebook; people with early psychosis could use this to “look at successful adults across a wide range of careers and how they had navigated accommodations, disclosure, education as well as vocational choice,” she said.

Dr. Jones did not ask participants about their gender and race, but she did query them on highest degree earned. The poll was disseminated with the assistance of the National Alliance on Mental Illness and that of Stanford (Calif.) University, where Dr. Jones was a postdoctoral fellow. Of the sample presented, 33% had a masters degree (MSW, MBA), and 15% had a doctoral level degree (JD, MD, PhD).

People who worked in fields outside of mental health care were far less likely to have revealed their conditions to colleagues or employers, with 14 of 67 participants having made no disclosure. Of 14 who had made no disclosure, 12 were in fields such as banking, economics, secondary education, nursing, pediatrics, and computer programming.

Dr. Jones said she received several calls from students and staff at Stanford who were unwilling to fill out the survey.

“They were very concerned about the risks of inadvertent disclosure, even though it was anonymous, because they had unique, potentially identifiable career paths that they could not lay out in their responses without the fear that that would disclose [identify] them,” Dr. Jones said.

An additional 17 of the 67 participants made what Dr. Jones termed “selective disclosures,” such as telling a coworker who was considered a friend or a supportive boss. The majority of the respondents to Jones’s survey – 36 of the 67 participants – were open about their conditions. All but one of the respondents in this broad-disclosure group worked in mental health fields.

Dr. Jones described the broad-disclosure designation as “meaning that there is nobody in their life who doesn’t know.”

“They’re out professionally. They’ve published a book. They speak,” Dr. Jones said. “If you Google them on the Internet, you would quickly learn that they had a psychiatric disability or psychosis.”

Dr. Jones herself falls into that camp. She’s told media outlets, including the online newspaper MinnPost, about her own experience being diagnosed with schizophrenia while a PhD student. The online magazine Pacific Standard ran a full-length feature about her return to academia.

 

 


About 100,000 adolescents and young adults in the United States experience first-episode psychosis each year, and the peak onset hits between 15 and 25 years of age, according to the NIMH. About a decade ago, the NIMH launched its Recovery After an Initial Schizophrenia Episode (RAISE) initiative to examine use of coordinated specialty care treatments for people who were experiencing a first episode of psychosis. Congress in 2014 moved to provide a stream of federal funding for those kinds of efforts.

“We’re going to be soon starting to discharge, on an annual basis, potentially tens of thousands of young people from these specialized early intervention programs,” Dr. Jones said. “So it becomes really pressing to understand what’s happening to them in the context of reintegration.”

Another presenter at the panel, Marjorie L. Baldwin, PhD, of Arizona State University, Tempe, is an economist who has published a book based, in part, on her son’s struggles, “Beyond Schizophrenia: Living and Working With a Serious Mental Illness” (Lanham, Md.: Rowman & Littlefield Publishers, 2016).

She presented findings from a pilot study for a larger project looking at the issue of disclosures of serious mental illness in the workplace. She and her colleague in this work, Steven C. Marcus, PhD, of the University of Pennsylvania, Philadelphia, separately spoke about the difficulties in securing funding for the project, including five failed R01 grant applications.

“The 6th time was the charm with NIH,” Dr. Baldwin said.

An initial hurdle was finding a cost-effective way to identify workers with serious mental illness who hold or have held what she termed “competitive jobs,” which Dr. Baldwin described as those that paid at least minimum wage and are not subsidized for people with disabilities.

“You cannot do this kind of a study with random dialing because it would be way too expensive,” she said. “Schizophrenia and serious mental illnesses are not rare, but they are fairly uncommon.”

Several years ago, though, she learned of a long-running health survey into which she could “piggyback” questions on mental health status. She presented results of a pilot study with about 230 people with serious mental illness who had held or had competitive jobs. Of this group, 52% had left their most recent job for reasons other than mental illness, while those conditions had caused an additional 21% to leave. But Dr. Baldwin and her colleagues found 27% still working.

Like Dr. Jones, Dr. Baldwin said some of those workers were in professional fields, such as accounting, law, education; others worked in the service and construction industries.

“Contrary to the stereotypes, people with serious mental illness whose symptoms are reasonably well controlled can work, and many are capable of supporting themselves in mainstream competitive jobs,” Dr. Baldwin said.

Dr. Jones had no disclosures tied to her survey. Dr. Baldwin and Dr. Marcus had no disclosures other than the NIH R01 grant.

 

– People working in the mental health field are more likely to disclose their past or present treatment for psychosis than are professionals in other fields, a researcher said at a National Institute of Mental Health conference on mental health services research.

The researcher, Nev Jones, PhD, presented the findings of a small survey she conducted in 2014 and 2015 of adults with current or past experiences of psychotic disorder who described themselves as having had or having a successful career. The research was not conducted for publication purposes but as part of an effort to develop tools for students with psychosis as they continued in higher education, said Dr. Jones, of the department of mental health law and policy at the University of South Florida, Tampa.

One of those tools was a closed program that was akin to Facebook; people with early psychosis could use this to “look at successful adults across a wide range of careers and how they had navigated accommodations, disclosure, education as well as vocational choice,” she said.

Dr. Jones did not ask participants about their gender and race, but she did query them on highest degree earned. The poll was disseminated with the assistance of the National Alliance on Mental Illness and that of Stanford (Calif.) University, where Dr. Jones was a postdoctoral fellow. Of the sample presented, 33% had a masters degree (MSW, MBA), and 15% had a doctoral level degree (JD, MD, PhD).

People who worked in fields outside of mental health care were far less likely to have revealed their conditions to colleagues or employers, with 14 of 67 participants having made no disclosure. Of 14 who had made no disclosure, 12 were in fields such as banking, economics, secondary education, nursing, pediatrics, and computer programming.

Dr. Jones said she received several calls from students and staff at Stanford who were unwilling to fill out the survey.

“They were very concerned about the risks of inadvertent disclosure, even though it was anonymous, because they had unique, potentially identifiable career paths that they could not lay out in their responses without the fear that that would disclose [identify] them,” Dr. Jones said.

An additional 17 of the 67 participants made what Dr. Jones termed “selective disclosures,” such as telling a coworker who was considered a friend or a supportive boss. The majority of the respondents to Jones’s survey – 36 of the 67 participants – were open about their conditions. All but one of the respondents in this broad-disclosure group worked in mental health fields.

Dr. Jones described the broad-disclosure designation as “meaning that there is nobody in their life who doesn’t know.”

“They’re out professionally. They’ve published a book. They speak,” Dr. Jones said. “If you Google them on the Internet, you would quickly learn that they had a psychiatric disability or psychosis.”

Dr. Jones herself falls into that camp. She’s told media outlets, including the online newspaper MinnPost, about her own experience being diagnosed with schizophrenia while a PhD student. The online magazine Pacific Standard ran a full-length feature about her return to academia.

 

 


About 100,000 adolescents and young adults in the United States experience first-episode psychosis each year, and the peak onset hits between 15 and 25 years of age, according to the NIMH. About a decade ago, the NIMH launched its Recovery After an Initial Schizophrenia Episode (RAISE) initiative to examine use of coordinated specialty care treatments for people who were experiencing a first episode of psychosis. Congress in 2014 moved to provide a stream of federal funding for those kinds of efforts.

“We’re going to be soon starting to discharge, on an annual basis, potentially tens of thousands of young people from these specialized early intervention programs,” Dr. Jones said. “So it becomes really pressing to understand what’s happening to them in the context of reintegration.”

Another presenter at the panel, Marjorie L. Baldwin, PhD, of Arizona State University, Tempe, is an economist who has published a book based, in part, on her son’s struggles, “Beyond Schizophrenia: Living and Working With a Serious Mental Illness” (Lanham, Md.: Rowman & Littlefield Publishers, 2016).

She presented findings from a pilot study for a larger project looking at the issue of disclosures of serious mental illness in the workplace. She and her colleague in this work, Steven C. Marcus, PhD, of the University of Pennsylvania, Philadelphia, separately spoke about the difficulties in securing funding for the project, including five failed R01 grant applications.

“The 6th time was the charm with NIH,” Dr. Baldwin said.

An initial hurdle was finding a cost-effective way to identify workers with serious mental illness who hold or have held what she termed “competitive jobs,” which Dr. Baldwin described as those that paid at least minimum wage and are not subsidized for people with disabilities.

“You cannot do this kind of a study with random dialing because it would be way too expensive,” she said. “Schizophrenia and serious mental illnesses are not rare, but they are fairly uncommon.”

Several years ago, though, she learned of a long-running health survey into which she could “piggyback” questions on mental health status. She presented results of a pilot study with about 230 people with serious mental illness who had held or had competitive jobs. Of this group, 52% had left their most recent job for reasons other than mental illness, while those conditions had caused an additional 21% to leave. But Dr. Baldwin and her colleagues found 27% still working.

Like Dr. Jones, Dr. Baldwin said some of those workers were in professional fields, such as accounting, law, education; others worked in the service and construction industries.

“Contrary to the stereotypes, people with serious mental illness whose symptoms are reasonably well controlled can work, and many are capable of supporting themselves in mainstream competitive jobs,” Dr. Baldwin said.

Dr. Jones had no disclosures tied to her survey. Dr. Baldwin and Dr. Marcus had no disclosures other than the NIH R01 grant.

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NIMH urged to shift priorities toward children’s mental health

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ROCKVILLE, MD. – A researcher is calling for a major shift in funding and priorities within the National Institute of Mental Health to seize on ripe opportunities to better understand how social and environmental factors affect the development of children’s brains.

Kimberly E. Hoagwood, PhD, of NYU Langone Health
Dr. Kimberly E. Hoagwood


“This new agenda that I’m suggesting would prioritize child and family health over other populations,” Kimberly E. Hoagwood, PhD, of NYU Langone Health, said at a National Institute of Mental Health conference on mental health services research. “But if we want science to maximize the public health impact and we want our services implementation research to have the biggest impact, then I think we have to think about rebalancing the portfolio.”

Dr. Hoagwood made her argument during a well-received presentation at the meeting. In an interview afterward, Dr. Hoagwood confirmed that she’s advocating for a potential shifting of funds from basic neuroscience.

She previously argued a case for rebalancing priorities within mental health research in a paper published in the Journal of the American Academy of Child and Adolescent Psychiatry (2018 Jan;57[1]:10-3). In the paper, Dr. Hoagwood and her coauthors said the NIMH’s annual funding for child and adolescent services and intervention research decreased 42%, to $30.2 million, from fiscal 2005 to fiscal 2015.

“The NIMH made an explicit decision to invest in basic neuroscience in part because of concerns about the inadequacy of the diagnostic classification systems and limited understanding of the etiology of mental illness,” Dr. Hoagwood and her colleagues wrote in the paper. “This investment could well pay off in the future. However, at least 20% of children now suffer from mental health problems. They cannot be ignored.”

The share of NIMH’s annual budget dedicated to child and adolescent services and intervention research has hovered around 2%-3% in recent years, according to Dr. Hoagwood.

She argued that increased investment in child and adolescent services and intervention research is needed in part because of a flourishing atmosphere outside of the NIMH. At least two dozen notable initiatives looking at social and environmental factors are underway that could contribute greatly to the understanding of factors outside of genetics that influence early brain development, Dr. Hoagwood said.

Those initiatives include about a dozen Medicaid accountable care organizations that are identifying social risks such as poverty, homelessness, food insecurity, and unemployment. Efforts aimed at addressing the effects of poverty through the adoption of strategies such as living wage laws also are underway, she said.

Dr. Hoagwood highlighted the importance of work on the exposome, which the NIMH has described as a new approach to understanding the mechanisms by which environmental factors alter brain and behavior – starting from prenatal development. Dr. Hoagwood said this approach would collect samples to systematically monitor a range of broad-spectrum environmental exposures. She described it as the “complement to the genomic sequencing.”

Exposures in children’s early years to factors such as concentrated poverty can set trajectories for life, Dr. Hoagwood said. She called for launching multisite studies to look at how such factors affect brain development, and where and how early interventions can improve children’s healthy development. Data from community efforts and some of those experiments might, at least initially, be “messy beyond belief,” she said.

“We have to not shy away from it. The genomic sequencing has not shied away from messy data,” Dr. Hoagwood said. “We don’t need to do that, either. We need new methods. We need small experiments of novel payment approaches. We need to use our data systems better.”

Dr. Hoagwood had no financial disclosures to report.

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ROCKVILLE, MD. – A researcher is calling for a major shift in funding and priorities within the National Institute of Mental Health to seize on ripe opportunities to better understand how social and environmental factors affect the development of children’s brains.

Kimberly E. Hoagwood, PhD, of NYU Langone Health
Dr. Kimberly E. Hoagwood


“This new agenda that I’m suggesting would prioritize child and family health over other populations,” Kimberly E. Hoagwood, PhD, of NYU Langone Health, said at a National Institute of Mental Health conference on mental health services research. “But if we want science to maximize the public health impact and we want our services implementation research to have the biggest impact, then I think we have to think about rebalancing the portfolio.”

Dr. Hoagwood made her argument during a well-received presentation at the meeting. In an interview afterward, Dr. Hoagwood confirmed that she’s advocating for a potential shifting of funds from basic neuroscience.

She previously argued a case for rebalancing priorities within mental health research in a paper published in the Journal of the American Academy of Child and Adolescent Psychiatry (2018 Jan;57[1]:10-3). In the paper, Dr. Hoagwood and her coauthors said the NIMH’s annual funding for child and adolescent services and intervention research decreased 42%, to $30.2 million, from fiscal 2005 to fiscal 2015.

“The NIMH made an explicit decision to invest in basic neuroscience in part because of concerns about the inadequacy of the diagnostic classification systems and limited understanding of the etiology of mental illness,” Dr. Hoagwood and her colleagues wrote in the paper. “This investment could well pay off in the future. However, at least 20% of children now suffer from mental health problems. They cannot be ignored.”

The share of NIMH’s annual budget dedicated to child and adolescent services and intervention research has hovered around 2%-3% in recent years, according to Dr. Hoagwood.

She argued that increased investment in child and adolescent services and intervention research is needed in part because of a flourishing atmosphere outside of the NIMH. At least two dozen notable initiatives looking at social and environmental factors are underway that could contribute greatly to the understanding of factors outside of genetics that influence early brain development, Dr. Hoagwood said.

Those initiatives include about a dozen Medicaid accountable care organizations that are identifying social risks such as poverty, homelessness, food insecurity, and unemployment. Efforts aimed at addressing the effects of poverty through the adoption of strategies such as living wage laws also are underway, she said.

Dr. Hoagwood highlighted the importance of work on the exposome, which the NIMH has described as a new approach to understanding the mechanisms by which environmental factors alter brain and behavior – starting from prenatal development. Dr. Hoagwood said this approach would collect samples to systematically monitor a range of broad-spectrum environmental exposures. She described it as the “complement to the genomic sequencing.”

Exposures in children’s early years to factors such as concentrated poverty can set trajectories for life, Dr. Hoagwood said. She called for launching multisite studies to look at how such factors affect brain development, and where and how early interventions can improve children’s healthy development. Data from community efforts and some of those experiments might, at least initially, be “messy beyond belief,” she said.

“We have to not shy away from it. The genomic sequencing has not shied away from messy data,” Dr. Hoagwood said. “We don’t need to do that, either. We need new methods. We need small experiments of novel payment approaches. We need to use our data systems better.”

Dr. Hoagwood had no financial disclosures to report.

 

ROCKVILLE, MD. – A researcher is calling for a major shift in funding and priorities within the National Institute of Mental Health to seize on ripe opportunities to better understand how social and environmental factors affect the development of children’s brains.

Kimberly E. Hoagwood, PhD, of NYU Langone Health
Dr. Kimberly E. Hoagwood


“This new agenda that I’m suggesting would prioritize child and family health over other populations,” Kimberly E. Hoagwood, PhD, of NYU Langone Health, said at a National Institute of Mental Health conference on mental health services research. “But if we want science to maximize the public health impact and we want our services implementation research to have the biggest impact, then I think we have to think about rebalancing the portfolio.”

Dr. Hoagwood made her argument during a well-received presentation at the meeting. In an interview afterward, Dr. Hoagwood confirmed that she’s advocating for a potential shifting of funds from basic neuroscience.

She previously argued a case for rebalancing priorities within mental health research in a paper published in the Journal of the American Academy of Child and Adolescent Psychiatry (2018 Jan;57[1]:10-3). In the paper, Dr. Hoagwood and her coauthors said the NIMH’s annual funding for child and adolescent services and intervention research decreased 42%, to $30.2 million, from fiscal 2005 to fiscal 2015.

“The NIMH made an explicit decision to invest in basic neuroscience in part because of concerns about the inadequacy of the diagnostic classification systems and limited understanding of the etiology of mental illness,” Dr. Hoagwood and her colleagues wrote in the paper. “This investment could well pay off in the future. However, at least 20% of children now suffer from mental health problems. They cannot be ignored.”

The share of NIMH’s annual budget dedicated to child and adolescent services and intervention research has hovered around 2%-3% in recent years, according to Dr. Hoagwood.

She argued that increased investment in child and adolescent services and intervention research is needed in part because of a flourishing atmosphere outside of the NIMH. At least two dozen notable initiatives looking at social and environmental factors are underway that could contribute greatly to the understanding of factors outside of genetics that influence early brain development, Dr. Hoagwood said.

Those initiatives include about a dozen Medicaid accountable care organizations that are identifying social risks such as poverty, homelessness, food insecurity, and unemployment. Efforts aimed at addressing the effects of poverty through the adoption of strategies such as living wage laws also are underway, she said.

Dr. Hoagwood highlighted the importance of work on the exposome, which the NIMH has described as a new approach to understanding the mechanisms by which environmental factors alter brain and behavior – starting from prenatal development. Dr. Hoagwood said this approach would collect samples to systematically monitor a range of broad-spectrum environmental exposures. She described it as the “complement to the genomic sequencing.”

Exposures in children’s early years to factors such as concentrated poverty can set trajectories for life, Dr. Hoagwood said. She called for launching multisite studies to look at how such factors affect brain development, and where and how early interventions can improve children’s healthy development. Data from community efforts and some of those experiments might, at least initially, be “messy beyond belief,” she said.

“We have to not shy away from it. The genomic sequencing has not shied away from messy data,” Dr. Hoagwood said. “We don’t need to do that, either. We need new methods. We need small experiments of novel payment approaches. We need to use our data systems better.”

Dr. Hoagwood had no financial disclosures to report.

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Judge seeks replication of efforts to support people with SMI

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Florida’s Miami-Dade County reportedly has the largest percentage of residents with serious mental illnesses (SMI) among large U.S. communities. And a Florida judge who helped develop approaches aimed at sparing his state’s residents with mental illness from harmful, avoidable, and expensive bouts of prison time wants to see his strategies replicated.

Judge Steve Leifman of the 11th judicial circuit court in Miami-Dade County, Florida
Courtesy Judge Steve Leifman
Judge Steve Leifman

“There is something terribly wrong with a society that is willing to spend more money to incarcerate people who are ill than to treat them,” Judge Steve Leifman of the 11th judicial circuit court said at a National Institute of Mental Health conference on mental health services research.

Judge Leifman in 2000 created the Criminal Mental Health Project. It’s been recognized for its success in keeping people with SMI from becoming ensnared in the criminal justice system because of minor offenses. It also helps those who do spend time in jail from returning.

In Miami-Dade County, for example, 97 people were a significant driver of costs in the criminal justice system in a study that was completed in 2010, Judge Leifman said. The members of this group were largely men who suffered from schizophrenia spectrum disorders and were homeless with a co-occurring disorder. Combined, the number of arrests for this group was about 2,200 over a 5-year period, Judge Leifman said. They spent 27,000 days in the Miami-Dade County jail – costing taxpayers about $13.7 million.

“We joke, but it’s true. It would have been cheaper and more effective to send them to Harvard,” Judge Leifman said. “They would have had a shot at an education. They would have had housing. They probably would have done a lot better.”

Through the Criminal Mental Health Project, Judge Leifman and his colleagues seek to both prevent people with mental illness from being arrested and jailed for minor offenses, and to provide a support network for those who have reached jail. The project’s “prebooking diversion” efforts are built on a model developed in Memphis, Tenn., in the late 1980s. Through it, police officers get special training in recognizing mental illness and resolving crises in which people who have these disorders are involved.

The project’s “postbooking diversion” techniques require participants to voluntarily consent to mental health treatment and services. The program is open only to those less serious felonies, which can include drug charges and theft. Through participation in the Criminal Mental Health Project, people can have charges dismissed or reduced. The program provides them with connections to community-based treatment, support, and housing services, according to its website.

Participants in the program who were charged with minor felonies had 75% fewer jail bookings and jail days after enrolling in the Criminal Mental Health Project (N Engl J Med. 2016;374:1701-3).

Judge Leifman said the postbooking jail diversion program has, since 2001, served more than 4,000 individuals. Recidivism rates among participants charged with misdemeanors dropped from roughly 75% to 20%, he said.

Still, Judge Leifman describes his role as a judge as making him a “gatekeeper to the largest psychiatric facility in Florida – the Miami-Dade County Jail.” The jail houses about 1,200 people with serious mental illness on any given day, according to the Criminal Mental Health Project’s website.

Judge Leifman said that, ultimately, he wants more communities to devote more resources to providing medical care for people with mental illness.

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Florida’s Miami-Dade County reportedly has the largest percentage of residents with serious mental illnesses (SMI) among large U.S. communities. And a Florida judge who helped develop approaches aimed at sparing his state’s residents with mental illness from harmful, avoidable, and expensive bouts of prison time wants to see his strategies replicated.

Judge Steve Leifman of the 11th judicial circuit court in Miami-Dade County, Florida
Courtesy Judge Steve Leifman
Judge Steve Leifman

“There is something terribly wrong with a society that is willing to spend more money to incarcerate people who are ill than to treat them,” Judge Steve Leifman of the 11th judicial circuit court said at a National Institute of Mental Health conference on mental health services research.

Judge Leifman in 2000 created the Criminal Mental Health Project. It’s been recognized for its success in keeping people with SMI from becoming ensnared in the criminal justice system because of minor offenses. It also helps those who do spend time in jail from returning.

In Miami-Dade County, for example, 97 people were a significant driver of costs in the criminal justice system in a study that was completed in 2010, Judge Leifman said. The members of this group were largely men who suffered from schizophrenia spectrum disorders and were homeless with a co-occurring disorder. Combined, the number of arrests for this group was about 2,200 over a 5-year period, Judge Leifman said. They spent 27,000 days in the Miami-Dade County jail – costing taxpayers about $13.7 million.

“We joke, but it’s true. It would have been cheaper and more effective to send them to Harvard,” Judge Leifman said. “They would have had a shot at an education. They would have had housing. They probably would have done a lot better.”

Through the Criminal Mental Health Project, Judge Leifman and his colleagues seek to both prevent people with mental illness from being arrested and jailed for minor offenses, and to provide a support network for those who have reached jail. The project’s “prebooking diversion” efforts are built on a model developed in Memphis, Tenn., in the late 1980s. Through it, police officers get special training in recognizing mental illness and resolving crises in which people who have these disorders are involved.

The project’s “postbooking diversion” techniques require participants to voluntarily consent to mental health treatment and services. The program is open only to those less serious felonies, which can include drug charges and theft. Through participation in the Criminal Mental Health Project, people can have charges dismissed or reduced. The program provides them with connections to community-based treatment, support, and housing services, according to its website.

Participants in the program who were charged with minor felonies had 75% fewer jail bookings and jail days after enrolling in the Criminal Mental Health Project (N Engl J Med. 2016;374:1701-3).

Judge Leifman said the postbooking jail diversion program has, since 2001, served more than 4,000 individuals. Recidivism rates among participants charged with misdemeanors dropped from roughly 75% to 20%, he said.

Still, Judge Leifman describes his role as a judge as making him a “gatekeeper to the largest psychiatric facility in Florida – the Miami-Dade County Jail.” The jail houses about 1,200 people with serious mental illness on any given day, according to the Criminal Mental Health Project’s website.

Judge Leifman said that, ultimately, he wants more communities to devote more resources to providing medical care for people with mental illness.

 

Florida’s Miami-Dade County reportedly has the largest percentage of residents with serious mental illnesses (SMI) among large U.S. communities. And a Florida judge who helped develop approaches aimed at sparing his state’s residents with mental illness from harmful, avoidable, and expensive bouts of prison time wants to see his strategies replicated.

Judge Steve Leifman of the 11th judicial circuit court in Miami-Dade County, Florida
Courtesy Judge Steve Leifman
Judge Steve Leifman

“There is something terribly wrong with a society that is willing to spend more money to incarcerate people who are ill than to treat them,” Judge Steve Leifman of the 11th judicial circuit court said at a National Institute of Mental Health conference on mental health services research.

Judge Leifman in 2000 created the Criminal Mental Health Project. It’s been recognized for its success in keeping people with SMI from becoming ensnared in the criminal justice system because of minor offenses. It also helps those who do spend time in jail from returning.

In Miami-Dade County, for example, 97 people were a significant driver of costs in the criminal justice system in a study that was completed in 2010, Judge Leifman said. The members of this group were largely men who suffered from schizophrenia spectrum disorders and were homeless with a co-occurring disorder. Combined, the number of arrests for this group was about 2,200 over a 5-year period, Judge Leifman said. They spent 27,000 days in the Miami-Dade County jail – costing taxpayers about $13.7 million.

“We joke, but it’s true. It would have been cheaper and more effective to send them to Harvard,” Judge Leifman said. “They would have had a shot at an education. They would have had housing. They probably would have done a lot better.”

Through the Criminal Mental Health Project, Judge Leifman and his colleagues seek to both prevent people with mental illness from being arrested and jailed for minor offenses, and to provide a support network for those who have reached jail. The project’s “prebooking diversion” efforts are built on a model developed in Memphis, Tenn., in the late 1980s. Through it, police officers get special training in recognizing mental illness and resolving crises in which people who have these disorders are involved.

The project’s “postbooking diversion” techniques require participants to voluntarily consent to mental health treatment and services. The program is open only to those less serious felonies, which can include drug charges and theft. Through participation in the Criminal Mental Health Project, people can have charges dismissed or reduced. The program provides them with connections to community-based treatment, support, and housing services, according to its website.

Participants in the program who were charged with minor felonies had 75% fewer jail bookings and jail days after enrolling in the Criminal Mental Health Project (N Engl J Med. 2016;374:1701-3).

Judge Leifman said the postbooking jail diversion program has, since 2001, served more than 4,000 individuals. Recidivism rates among participants charged with misdemeanors dropped from roughly 75% to 20%, he said.

Still, Judge Leifman describes his role as a judge as making him a “gatekeeper to the largest psychiatric facility in Florida – the Miami-Dade County Jail.” The jail houses about 1,200 people with serious mental illness on any given day, according to the Criminal Mental Health Project’s website.

Judge Leifman said that, ultimately, he wants more communities to devote more resources to providing medical care for people with mental illness.

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