Perioperative major adverse cardiovascular and cerebrovascular events (MACCEs) were more common among patients with diabetes mellitus (DM) vs without DM in an analysis of noncardiac surgeries. The analysis of >10.5 million noncardiac surgeries from a large US hospital admission included patients aged >45 years who underwent noncardiac surgery from January 2004 to December 2013. Perioperative MACCEs by DM status were evaluated over time. Researchers found:

• DM was present in ∼23% of surgeries and increased over time.
• Patients with DM experienced MACCEs in 3.3% of surgeries vs 2.8% of surgeries without DM.
• The odds of perioperative MACCEs after multivariable adjustment increased by 6% for DM patients vs an 8% decrease for patients without DM during the study period.
• Trends for individual end points were all less favorable for patients with DM vs those without DM.