Edited by Shrabasti Bhattacharya

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All rights reserved. This material may not be published, broadcast, copied, or otherwise reproduced or distributed without the prior written permission of Frontline Medical Communications Inc.</copyrightNotice> </rightsInfo> </provider> <abstract/> <metaDescription>Compared with the general population, patients with urticaria had a 49% higher risk of developing cancer in the first year following diagnosis,</metaDescription> <articlePDF/> <teaserImage/> <teaser>Researchers compare the incident cancer risk between patients with urticaria and the general population using data from Danish healthcare registries.</teaser> <title>Urticaria Linked to Higher Cancer Risk, Study Finds</title> <deck/> <disclaimer/> <AuthorList/> <articleURL/> <doi/> <pubMedID/> <publishXMLStatus/> <publishXMLVersion>1</publishXMLVersion> <useEISSN>0</useEISSN> <urgency/> <pubPubdateYear/> <pubPubdateMonth/> <pubPubdateDay/> <pubVolume/> <pubNumber/> <wireChannels/> <primaryCMSID/> <CMSIDs/> <keywords/> <seeAlsos/> <publications_g> <publicationData> <publicationCode>oncr</publicationCode> <pubIssueName/> <pubArticleType/> <pubTopics/> <pubCategories/> <pubSections/> </publicationData> <publicationData> <publicationCode>pn</publicationCode> <pubIssueName/> <pubArticleType/> <pubTopics/> <pubCategories/> <pubSections/> </publicationData> <publicationData> <publicationCode>im</publicationCode> <pubIssueName/> <pubArticleType/> <pubTopics/> <pubCategories/> <pubSections/> </publicationData> <publicationData> <publicationCode>fp</publicationCode> <pubIssueName/> <pubArticleType/> <pubTopics/> <pubCategories/> <pubSections/> </publicationData> <publicationData> <publicationCode>hemn</publicationCode> <pubIssueName/> <pubArticleType/> <pubTopics/> <pubCategories/> <pubSections/> </publicationData> <publicationData> <publicationCode>endo</publicationCode> <pubIssueName/> <pubArticleType/> <pubTopics/> <pubCategories/> <pubSections/> </publicationData> <publicationData> <publicationCode>chph</publicationCode> <pubIssueName/> <pubArticleType/> <pubTopics/> <pubCategories/> <pubSections/> </publicationData> <publicationData> <publicationCode>ob</publicationCode> <pubIssueName/> <pubArticleType/> <pubTopics/> <pubCategories/> <pubSections/> </publicationData> <publicationData> <publicationCode>nr</publicationCode> <pubIssueName/> <pubArticleType/> <pubTopics/> <pubCategories/> <pubSections/> <journalTitle>Neurology Reviews</journalTitle> <journalFullTitle>Neurology Reviews</journalFullTitle> <copyrightStatement>2018 Frontline Medical Communications Inc.,</copyrightStatement> </publicationData> </publications_g> <publications> <term>31</term> <term>25</term> <term>21</term> <term>15</term> <term canonical="true">18</term> <term>34</term> <term>6</term> <term>23</term> <term>22</term> </publications> <sections> <term>39313</term> <term canonical="true">27970</term> </sections> <topics> <term>270</term> <term>244</term> <term>245</term> <term>263</term> <term>203</term> <term canonical="true">37637</term> <term>179</term> <term>178</term> <term>181</term> <term>59374</term> <term>196</term> <term>197</term> <term>233</term> <term>243</term> <term>27442</term> <term>250</term> <term>49434</term> <term>303</term> <term>271</term> <term>61821</term> <term>192</term> <term>198</term> <term>59244</term> <term>67020</term> <term>214</term> <term>217</term> <term>221</term> <term>238</term> <term>240</term> <term>242</term> <term>39570</term> <term>256</term> <term>292</term> <term>31848</term> <term>210</term> </topics> <links/> </header> <itemSet> <newsItem> <itemMeta> <itemRole>Main</itemRole> <itemClass>text</itemClass> <title>Urticaria Linked to Higher Cancer Risk, Study Finds</title> <deck/> </itemMeta> <itemContent> <h2>TOPLINE:</h2> <p><span class="tag metaDescription">Compared with the general population, patients with urticaria had a 49% higher risk of developing cancer in the first year following diagnosis,</span> which decreased to 6% in subsequent years, in a cohort study using Danish healthcare databases.</p> <h2>METHODOLOGY:</h2> <ul class="body"> <li>Researchers conducted a retrospective cohort study using data from Danish healthcare registries and compared the incident cancer risk between patients with urticaria and the risk in the general population.</li> <li>They identified 87,507 patients (58% women) with a primary or secondary first-time hospital outpatient clinic, emergency room, or inpatient diagnosis of urticaria between 1980 and 2022, who were followed for a median of 10.1 years.</li> <li>Incident cancers, including nonmelanoma skin cancer, were identified using the Danish Cancer Registry and classified by the extent of spread at the time of diagnosis.</li> <li>This study computed the absolute cancer risk within the first year of an urticaria diagnosis and standardized incidence ratios (SIRs), with 95% CIs standardized to Danish national cancer rates.</li> </ul> <h2>TAKEAWAY:</h2> <ul class="body"> <li>For the first year of follow-up, the absolute risk for all cancer types was 0.7%, and it was 29.5% for subsequent years. The overall SIR for all types of cancer was 1.09 (95% CI, 1.06-1.11), which was based on 7788 observed cancer cases compared with 7161 cases expected over the entire follow-up period.</li> <li>Within the first year of follow-up, 588 patients with urticaria were diagnosed with cancer, for an SIR of 1.49 (95% CI, 1.38-1.62) for all cancer types.</li> <li>After the first year, the SIR for all cancer sites decreased and stabilized at 1.06 (95% CI, 1.04-1.09), with 7200 observed cancer cases.</li> <li>The risk was highest for hematological cancers in the first year, particularly Hodgkin lymphoma (SIR, 5.35; 95% CI, 2.56-9.85).</li> </ul> <h2>IN PRACTICE:</h2> <p>“Our study suggests that urticaria may be a marker of occult cancer and that it is associated with a slightly increased long-term cancer risk,” the authors wrote.</p> <h2>SOURCE:</h2> <p>The study was led by Sissel B.T. Sørensen, departments of dermatology and rheumatology, Aarhus University Hospital, Aarhus, Denmark. It was published <a href="https://academic.oup.com/bjd/advance-article-abstract/doi/10.1093/bjd/ljae264/7699818?redirectedFrom=fulltext&amp;login=true">online</a> on June 27, 2024, in the <em>British Journal of Dermatology</em>.</p> <h2>LIMITATIONS:</h2> <p>The study is limited by its observational design and reliance on registry data, which may be subject to misclassification or incomplete information. In addition, the study could not assess individual patient factors such as lifestyle or genetic predispositions that may influence cancer risk, and the results may not be generalizable to other populations. Finally, the exact biologic mechanisms linking urticaria and cancer remain unclear, warranting further investigation.</p> <h2>DISCLOSURES:</h2> <p>The study did not receive any funding. The authors reported that they had no relevant conflicts of interest.</p> <p> <em>This article was created using several editorial tools, including AI, as part of the process. Human editors reviewed this content before publication. A version of this article first appeared on <span class="Hyperlink"><a href="https://www.medscape.com/viewarticle/urticaria-linked-higher-cancer-risk-study-finds-2024a1000cao">Medscape.com</a></span>.</em> </p> </itemContent> </newsItem> <newsItem> <itemMeta> <itemRole>teaser</itemRole> <itemClass>text</itemClass> <title/> <deck/> </itemMeta> <itemContent> </itemContent> </newsItem> </itemSet></root>

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<root generator="drupal.xsl" gversion="1.7"> <header> <fileName>168591</fileName> <TBEID>0C050D21.SIG</TBEID> <TBUniqueIdentifier>MD_0C050D21</TBUniqueIdentifier> <newsOrJournal>News</newsOrJournal> <publisherName>Frontline Medical Communications</publisherName> <storyname/> <articleType>2</articleType> <TBLocation>QC Done-All Pubs</TBLocation> <QCDate>20240702T094045</QCDate> <firstPublished>20240702T111341</firstPublished> <LastPublished>20240702T111341</LastPublished> <pubStatus qcode="stat:"/> <embargoDate/> <killDate/> <CMSDate>20240702T111341</CMSDate> <articleSource/> <facebookInfo/> <meetingNumber/> <byline>Shrabasti Bhattacharya</byline> <bylineText>EDITED SHRABASTI BHATTACHARYA AND LISA GILLESPIE</bylineText> <bylineFull>EDITED SHRABASTI BHATTACHARYA AND LISA GILLESPIE</bylineFull> <bylineTitleText/> <USOrGlobal/> <wireDocType/> <newsDocType>News</newsDocType> <journalDocType/> <linkLabel/> <pageRange/> <citation/> <quizID/> <indexIssueDate/> <itemClass qcode="ninat:text"/> <provider qcode="provider:imng"> <name>IMNG Medical Media</name> <rightsInfo> <copyrightHolder> <name>Frontline Medical News</name> </copyrightHolder> <copyrightNotice>Copyright (c) 2015 Frontline Medical News, a Frontline Medical Communications Inc. company. All rights reserved. This material may not be published, broadcast, copied, or otherwise reproduced or distributed without the prior written permission of Frontline Medical Communications Inc.</copyrightNotice> </rightsInfo> </provider> <abstract/> <metaDescription>follow-up visits and new antibiotic dispensations were rare regardless of treatment, suggesting that not receiving antibiotics may not lead to additional health</metaDescription> <articlePDF/> <teaserImage/> <teaser>Study: Additional antibiotics or follow-up care was uncommon in pink eye, suggesting initial antibiotics may not be needed.</teaser> <title>Reducing Unnecessary Antibiotics for Conjunctivitis</title> <deck/> <disclaimer/> <AuthorList/> <articleURL/> <doi/> <pubMedID/> <publishXMLStatus/> <publishXMLVersion>1</publishXMLVersion> <useEISSN>0</useEISSN> <urgency/> <pubPubdateYear/> <pubPubdateMonth/> <pubPubdateDay/> <pubVolume/> <pubNumber/> <wireChannels/> <primaryCMSID/> <CMSIDs/> <keywords/> <seeAlsos/> <publications_g> <publicationData> <publicationCode>idprac</publicationCode> <pubIssueName/> <pubArticleType/> <pubTopics/> <pubCategories/> <pubSections/> </publicationData> <publicationData> <publicationCode>fp</publicationCode> <pubIssueName/> <pubArticleType/> <pubTopics/> <pubCategories/> <pubSections/> </publicationData> <publicationData> <publicationCode>im</publicationCode> <pubIssueName/> <pubArticleType/> <pubTopics/> <pubCategories/> <pubSections/> </publicationData> <publicationData> <publicationCode>pn</publicationCode> <pubIssueName/> <pubArticleType/> <pubTopics/> <pubCategories/> <pubSections/> </publicationData> </publications_g> <publications> <term canonical="true">20</term> <term>15</term> <term>21</term> <term>25</term> </publications> <sections> <term canonical="true">39313</term> </sections> <topics> <term canonical="true">271</term> <term>234</term> </topics> <links/> </header> <itemSet> <newsItem> <itemMeta> <itemRole>Main</itemRole> <itemClass>text</itemClass> <title>Reducing Unnecessary Antibiotics for Conjunctivitis</title> <deck/> </itemMeta> <itemContent> <h2>TOPLINE:</h2> <p>More than two thirds of children with conjunctivitis received antibiotics within a day of their initial ambulatory care visit; however, <span class="tag metaDescription">follow-up visits and new antibiotic dispensations were rare regardless of treatment, suggesting that not receiving antibiotics may not lead to additional health care use.</span></p> <h2>METHODOLOGY:</h2> <ul class="body"> <li>Researchers evaluated the frequency of topical antibiotic treatment and its association with subsequent health care use among commercially insured children with acute infectious conjunctivitis in the United States.</li> <li>This cohort study analyzed data from the 2021 MarketScan Commercial Claims and Encounters Database, including 44,793 children with conjunctivitis (median age, 5 years; 47% girls) and ambulatory care encounters.</li> <li>The primary exposure was a topical antibiotic prescription dispensed within 1 day of an ambulatory care visit, with outcomes assessed 2-14 days after the visit.</li> <li>The primary outcomes were ambulatory care revisits for conjunctivitis and same-day dispensation of a new topical antibiotic, and secondary outcomes included emergency department revisits and hospitalizations.</li> </ul> <h2>TAKEAWAY:</h2> <ul class="body"> <li>Topical antibiotics were dispensed within a day of an ambulatory care visit in 69% of the cases; however, they were less frequently dispensed following visits to eye clinics (34%), for children aged 6-11 years (66%), and for those with viral conjunctivitis (28%).</li> <li>Ambulatory care revisits for conjunctivitis within 2 weeks occurred in only 3.2% of children who had received antibiotics (adjusted odds ratio [aOR], 1.11; 95% CI, 0.99-1.25).</li> <li>Similarly, revisits with same-day dispensation of a new antibiotic were also rare (1.4%), with no significant association between antibiotic treatment and revisits (aOR, 1.10; 95% CI, 0.92-1.33).</li> <li>Hospitalizations for conjunctivitis occurred in 0.03% of cases, and emergency department revisits occurred in 0.12%, with no differences between children who received antibiotics and those who did not.</li> </ul> <h2>IN PRACTICE:</h2> <p>“Given that antibiotics may not be associated with improved outcomes or change in subsequent health care use and are associated with adverse effects and antibiotic resistance, efforts to reduce overtreatment of acute infectious conjunctivitis are warranted,” the authors wrote.</p> <h2>SOURCE:</h2> <p>The study was led by Daniel J. Shapiro, MD, MPH, of the Department of Emergency Medicine at the University of California, San Francisco, and <a href="https://jamanetwork.com/journals/jamaophthalmology/article-abstract/2820326?utm_campaign=articlePDF&amp;utm_medium=articlePDFlink&amp;utm_source=articlePDF&amp;utm_content=jamaophthalmol.2024.2211">published online</a> on June 27, 2024, in <em>JAMA Ophthalmology</em>.</p> <h2>LIMITATIONS:</h2> <p>The major limitations of the study included the inability to distinguish scheduled visits from unscheduled revisits, incomplete clinical data such as rare complications of conjunctivitis, and the inability to confirm the accuracy of the coded diagnosis of infectious conjunctivitis, especially in children who did not receive a thorough eye examination.</p> <h2>DISCLOSURES:</h2> <p>This study did not declare receiving funding from any sources. One author reported receiving grants from several sources outside the submitted work.</p> <p> <em>This article was created using several editorial tools, including AI, as part of the process. Human editors reviewed this content before publication. A version of this article first appeared on <span class="Hyperlink"><a href="https://www.medscape.com/viewarticle/cutting-down-unnecessary-antibiotics-pink-eye-2024a1000c5p">Medscape.com</a></span>.</em> </p> </itemContent> </newsItem> <newsItem> <itemMeta> <itemRole>teaser</itemRole> <itemClass>text</itemClass> <title/> <deck/> </itemMeta> <itemContent> </itemContent> </newsItem> </itemSet></root>

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All rights reserved. This material may not be published, broadcast, copied, or otherwise reproduced or distributed without the prior written permission of Frontline Medical Communications Inc.</copyrightNotice> </rightsInfo> </provider> <abstract/> <metaDescription>A study found that patients who die by suicide within a year after discharge from inpatient mental health care are less likely to have primary care consultation</metaDescription> <articlePDF/> <teaserImage/> <teaser>Evidence of discharge communication between the inpatient facility and primary care clinician was infrequent, highlighting a gap in continuity of care.</teaser> <title>Study Links Suicide to Missed Early Care After Discharge</title> <deck/> <disclaimer/> <AuthorList/> <articleURL/> <doi/> <pubMedID/> <publishXMLStatus/> <publishXMLVersion>1</publishXMLVersion> <useEISSN>0</useEISSN> <urgency/> <pubPubdateYear/> <pubPubdateMonth/> <pubPubdateDay/> <pubVolume/> <pubNumber/> <wireChannels/> <primaryCMSID/> <CMSIDs/> <keywords/> <seeAlsos/> <publications_g> <publicationData> <publicationCode>cpn</publicationCode> <pubIssueName/> <pubArticleType/> <pubTopics/> <pubCategories/> <pubSections/> </publicationData> <publicationData> <publicationCode>fp</publicationCode> <pubIssueName/> <pubArticleType/> <pubTopics/> <pubCategories/> <pubSections/> </publicationData> <publicationData> <publicationCode>im</publicationCode> <pubIssueName/> <pubArticleType/> <pubTopics/> <pubCategories/> <pubSections/> </publicationData> </publications_g> <publications> <term canonical="true">9</term> <term>15</term> <term>21</term> </publications> <sections> <term>27970</term> <term canonical="true">39313</term> </sections> <topics> <term canonical="true">61423</term> <term>248</term> <term>202</term> </topics> <links/> </header> <itemSet> <newsItem> <itemMeta> <itemRole>Main</itemRole> <itemClass>text</itemClass> <title>Study Links Suicide to Missed Early Care After Discharge</title> <deck/> </itemMeta> <itemContent> <h2>TOPLINE:</h2> <p>A study found that patients who die by suicide within a year after discharge from inpatient mental health care are less likely to have primary care consultation in the first 2 weeks, highlighting a gap during the high-risk transition period.</p> <h2>METHODOLOGY:</h2> <ul class="body"> <li>Researchers used a nested case-control study design, analyzing the records of 613 people who died by suicide within a year of being discharged from an inpatient psychiatric facility in England between 2001 and 2019.</li> <li>Of these, 93 (15.4%) died within 2 weeks of discharge.</li> <li>Each patient was matched with up to 20 control individuals who were discharged at a similar time but were living.</li> <li>Researchers evaluated primary care consultations after discharge.</li> </ul> <h2>TAKEAWAY:</h2> <ul class="body"> <li>People who died by suicide within a year were less likely to have had a primary care consultation within 2 weeks of discharge (adjusted odds ratio [aOR], 0.61; <em>P</em> = .01).</li> <li>Those who died by suicide had higher odds for a consultation in the week preceding their death (aOR, 1.71; <em>P</em> &lt; .001) and the prescription of three or more psychotropic medications (aOR, 1.73; <em>P</em> &lt; .001).</li> <li>Evidence of discharge communication between the facility and primary care clinician was infrequent, highlighting a gap in continuity of care.</li> <li>Approximately 40% of people who died within 2 weeks of discharge had a documented visit with a primary care clinician during that period.</li> </ul> <h2>IN PRACTICE:</h2> <p>“Primary care clinicians have opportunities to intervene and should prioritize patients experiencing transition from inpatient care,” the authors wrote.</p> <h2>SOURCE:</h2> <p>The study was led by Rebecca Musgrove, PhD, of the Centre for Mental Health and Safety at The University of Manchester in England, and published <a href="https://bjgpopen.org/content/early/2024/06/10/BJGPO.2023.0165">online on</a> June 12 in <em>BJGP Open</em>.</p> <h2>LIMITATIONS:</h2> <p>The study’s reliance on individuals registered with the Clinical Practice Research Datalink may have caused some suicide cases to be excluded, limiting generalizability. Lack of linked up-to-date mental health records may have led to the omission of significant post-discharge care data. Incomplete discharge documentation may undercount informational continuity, affecting multivariable analysis.</p> <h2>DISCLOSURES:</h2> <p>The study was supported by the National Institute of Health and Care Research. Some authors declared serving as members of advisory groups and receiving grants and personal fees from various sources.</p> <p> <em>This article was created using several editorial tools, including AI, as part of the process. Human editors reviewed this content before publication. A version of this article appeared on <span class="Hyperlink"><a href="https://www.medscape.com/viewarticle/study-links-suicide-missed-early-care-after-discharge-2024a1000c2y">Medscape.com</a></span>.</em> </p> </itemContent> </newsItem> <newsItem> <itemMeta> <itemRole>teaser</itemRole> <itemClass>text</itemClass> <title/> <deck/> </itemMeta> <itemContent> </itemContent> </newsItem> </itemSet></root>