News
Less Than 50% of Accelerated Approvals Show Clinical Benefit
- Author:
- M. Alexander Otto, PA, MMS
Researchers review 46 cancer drugs granted accelerated approvals between 2013 and 2017.
News
Abecma Approved for Earlier Lines in Relapsed/Refractory Multiple Myeloma
- Author:
- M. Alexander Otto, PA, MMS
The FDA greenlighted a costly CAR T-cell therapy for earlier lines in the treatment of adults with relapsed/refractory myeloma.
News
Eliminating H pylori Lowers CRC Incidence, Mortality Risk
- Author:
- M. Alexander Otto, PA, MMS
Investigators review CRC incidence and mortality in a nationwide cohort of veterans tested for H pylori.
News
Polygenic Risk Scores Improve Breast Cancer Screening
- Author:
- M. Alexander Otto, PA, MMS
Researchers examine how well polygenic risk scores predict a person's risk for any breast cancer as well as invasive, in situ, and bilateral at...
News
FDA OKs Danicopan Add-On for Extravascular Hemolysis in Adults With PNH
- Author:
- M. Alexander Otto, PA, MMS
Danicopan to support treatment of a rare blood disorder, paroxysmal nocturnal hemoglobinuria, is approved by the Food and Drug Administration.
News
Upfront Low-Dose Radiation Improves Advanced SCLC Outcomes
- Author:
- M. Alexander Otto, PA, MMS
Researchers compared their new findings with those of standard first-line treatment results from the 2019 CASPIAN trial.
News
FDA Approves Ponatinib for Upfront Ph+ ALL
- Author:
- M. Alexander Otto, PA, MMS
Accelerated approval of ponatinib in treating adults with a subtype of acute lymphoblastic leukemia has been granted by the FDA.
News
Zanubrutinib Label Expands to Include RR Follicular Lymphoma
- Author:
- M. Alexander Otto, PA, MMS
The FDA gives expedited approval to zanubrutinib for treating relapsed or refractory cases of the most common type of non-Hodgkin lymphoma.
News
Nivolumab Wins First-Line Indication in Metastatic Urothelial Carcinoma
- Author:
- M. Alexander Otto, PA, MMS
Median overall survival was 21.7 months with nivolumab add-on vs 18.9 months with cisplatin/gemcitabine alone.
News
Pfizer Antibody-Drug Conjugate Picks Up Pediatric ALL Indication
- Author:
- M. Alexander Otto, PA, MMS
The FDA has given pediatric approval for inotuzumab ozogamicin to treat some types of relapsed or refractory acute lymphoblastic leukemia.
News
Doxorubicin Increases Breast Cancer Risk in Women With Hodgkin Lymphoma
- Author:
- M. Alexander Otto, PA, MMS
Investigators review breast cancer incidence in nearly 2,000 women treated for Hodgkin lymphoma.
News
Transcatheter Arterial Chemoembolization for Rectal Tumors?
- Author:
- M. Alexander Otto, PA, MMS
Overall, 20.7% of patients undergoing transcatheter arterial chemoembolization had a pathological complete response.
News
Hyperbaric Oxygen: Effective Against Cancer Radiation Harm?
- Author:
- M. Alexander Otto, PA, MMS
New study on hyperbaric oxygen therapy does not clarify benefit for patients following radiation.
News
Regrowth Predicts Metastasis in Rectal Cancer Watch and Wait
- Author:
- M. Alexander Otto, PA, MMS
Investigators compared outcomes for ‘watch-and-wait’ patients with those who had total mesorectal excisions after neoadjuvant therapy.
News
The Case for Biomarker Testing in Gastroesophageal Cancer
- Author:
- M. Alexander Otto, PA, MMS
Expert provides top three picks for biomarker testing for treatment selection.