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Nail the Genetic Disorder


 

2. Six months ago, this 36-year-old man’s left fourth finger began to bother him. He’s tried topical antibiotics, colloidal silver solution, and two different oral antibiotics. None have relieved the pain, which is severe enough to interfere with daily activity—particularly his job, which requires extensive computer time.

Diagnosis: “Infection” is only one potential cause of redness, swelling, increased warmth, and localized pain. Classically termed rubor, tumor, calor, and dolor, these are indicators of inflammation, which can occur in many conditions besides “infection.” In the case described, a simple hangnail was incompletely removed, leaving a shard of nail that then dug into the perionychial skin as it grew out. This set into motion a healing process that could not proceed to resolution, because the tissue was re-injured every time the finger struck the computer keyboard. This not only caused the wound to get stuck in a certain phase of healing (angioneogenesis) but also prevented completion of the process.

For more information on this case, see “Red and Swollen Doesn’t Mean “Infection.” Clin Rev. 2014;24(6):W1.

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