Changes to how doctors are paid for drugs that are administered in-office could be on the way depending on the outcomes of two recent regulatory proposals from the Centers for Medicare and Medicaid Services. Also today, who are high-need, high-cost patients?, RA seroconversion is not associated with sustained drug-free remission, and a new myeloma frailty index based on biological cage. Listen to the MDedge Daily News for today’s top news.