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Menus for Managing Patients With Cutaneous T-Cell Lymphoma

The complex nature of the immunology of the skin is represented in the malignancy of one of the key participants—cutaneous T-cells—in cutaneous immune responses.


 

Brian Poligone, MD, PhD, and Peter Heald, MD

In the management of patients with cutaneous T-cell lymphoma (CTCL), there are numerous distinct therapy options. Each of these therapies is discussed in terms of when to use it, what factors limit the success of the treatment, and what to expect. A menu is defined as a list of items from which to choose. The treatments for CTCL are presented in various menus where they are options for a particular goal in a particular setting of CTCL. The best recognized clinical scenarios of CTCL are those recognized by the staging system: limited patch plaque (T1), disseminated patch plaque (T2), erythroderma (T4), and tumor (T3). Each phase of the disease will have the menu of therapy options presented for a given goal of management.

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