Cutaneous Metastasis of Uterine Adenocarcinoma: A Case Report and Review of the Literature
This article has been peer reviewed and approved by Ranon Ephraim Mann, MD, Assistant Professor, Department of Medicine (Dermatology), Albert Einstein College of Medicine. Review date: June 2009.
Drs. Selim, Shaheen, Lockshin, and Khachemoune report no conflict of interest. The authors report no discussion of off-label use. Dr. Mann reports no conflict of interest. The staff of CCME of Albert Einstein College of Medicine and Cutis® have no conflicts of interest with commercial interest related directly or indirectly to this educational activity. Dr. Selim is Assistant Professor, Biotechnology Center, King Fahd University of Petroleum & Minerals, Dhahran, Saudi Arabia. Dr. Shaheen is a resident physician, Department of Internal Medicine, Saint Joseph Hospital, Chicago, Illinois. Dr. Lockshin is a dermatologist, Derm Associates, Silver Spring, Maryland. Dr. Khachemoune is attending physician, Veterans Affairs Hospital, Brooklyn, New York.
Abdulhafez A. Selim, MD, PhD; Shagufta Shaheen, MD; Norman Lockshin, MD; Amor Khachemoune, MD, CWS
Cutaneous metastases from cancer are relatively uncommon in clinical practice but when present may herald the diagnosis of internal malignancy. The most common sources of primary cancer are the breasts, lungs, large bowel, oral cavity, kidneys, stomach, ovaries, and malignant melanoma. Despite the high incidence of uterine adenocarcinoma, cutaneous metastases are uncommon. The most common presentation of cutaneous metastases is rapidly developing nodules or tumors. The diagnosis of cutaneous metastatic carcinoma hinges on histopathologic evaluation of the involved skin. We discuss and review the diagnosis and management of cutaneous metastasis of uterine adenocarcinoma.