Article

Symmetrical Drug-Related Intertriginous and Flexural Exanthema Secondary to Topical 5-Fluorouracil

Cutis. 2012 May;89(5):225-228
By
Powers R
Gordon R
Roberts K
Kovach R
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We report the case of a 56-year-old man who developed a distinctive skin eruption after treating actinic keratoses on the dorsal aspects of his right and left hands with topical 5-fluorouracil (5-FU). The distribution of his rash was characteristic of symmetrical drug-related intertriginous and flexural exanthema (SDRIFE), also known as baboon syndrome.
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