In addition, the duration of CEE use in the WHI remains problematic since the median “adherent time” was 3.5 years. “Thus, the WHI results do not address the balance of risks and benefits associated with longer term estrogen use,” they said.
DR. JUNGHEIM and Dr. Colditz are at Washington University, St. Louis. These remarks were taken from their editorial comment accompanying Dr. LaCroix's report (JAMA 2011;305:1354-5). They reported no relevant financial disclosures.