Applied Evidence

Buprenorphine to treat opioid use disorder: A practical guide

Author and Disclosure Information

 

References

Four days later, Mr. R shows up at the clinic, apologizing for missing the appointment and assuring you that this won’t happen again. Rapid urine drug screening is positive for morphine. When confronted, he admits using heroin. He reports that his cravings had increased, for which he took buprenorphine and naloxone above the prescribed dosage, and ran out of films early. He then used heroin 3 times to prevent withdrawal.

In our experience, a common induction method is to give 2 to 4 mg buprenorphine, followed by a 1-hour assessment of withdrawal symptoms.

Mr. R admits that he has been having cravings for oxycodone since the start of treatment for addiction, but thought he was strong enough to overcome the cravings. He feels disappointed and embarrassed about this; he wants to continue with buprenorphine, he tells you, but worries that you will refuse to continue seeing him now.

Using shared decision-making, you opt to increase the buprenorphine dosage by 4 mg (to 16 mg/d—ie, 2 films of buprenorphine and naloxone, 8 mg/2 mg) to alleviate cravings. You instruct him to engage his support network, including his family and NA sponsor, and to start outpatient group therapy. He tells you that he is willing to go back to weekly clinic visits until he is stabilized.

CORRESPONDENCE
Tanner Nissly, DO, University of Minnesota Medical School Twin Cities, Department of Family Medicine and Community Health, 1020 West Broadway Avenue, Minneapolis, MN 55411; nissl003@umn.edu.

Pages

Recommended Reading

Opioid use has not declined meaningfully
MDedge Family Medicine
E-cigarettes: Prices down, sales up
MDedge Family Medicine
FDA proposes broader outcomes for OUD treatment drug approvals
MDedge Family Medicine
Barriers loom for HCV care in young people who inject drugs
MDedge Family Medicine
More deliveries now include opioid use disorder
MDedge Family Medicine
Treating sleep disorders in chronic opioid users
MDedge Family Medicine
Opioids, other causes linked to shorter lifespans, rising midlife mortality
MDedge Family Medicine
CDC: 2017 worst year yet for drug overdoses
MDedge Family Medicine
Witnessed overdose, HCV infection associated with greater opioid overdose risk
MDedge Family Medicine
Study examines the world of alcohol use
MDedge Family Medicine