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Adjustable Gastric Banding Shows Poor Long-Term Outcomes

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Data on LAGB Are Not Encouraging

"The data in this study, as well as the experience in our own institutions, should influence our choice of procedure [LAGB vs. laparoscopic Roux-en-Y gastric bypass] and the manner in which we inform our patients of the advantages and disadvantages of each procedure," said Dr. Clifford W. Deveney.

At long-term follow-up, patients who still had the band in place had lost 48% of their excess weight, and those who had had the band removed had lost 22% of their excess weight. Moreover, the number and type of obesity-related comorbidities increased over time.

"These data do not shed a favorable light on the use of LAGB," he noted.

Clifford W. Deveney, M.D., is in the department of surgery at Oregon Health and Science University, Portland. These remarks were taken from his "invited critique" accompanying Dr. Himpens’ report (Arch. Surg. 2011 March 21[doi:10.1001/archsurg.2011.36]). Dr. Deveney reported no financial disclosures.


 

FROM ARCHIVES OF SURGERY

The long-term outcomes of laparoscopic adjustable gastric banding appear to be relatively poor, according to a study published online March 21 in Archives of Surgery .

In a 13-year follow-up study of about half of the obese patients who underwent laparoscopic adjustable gastric banding (LAGB) at one institution between 1994 and 1997, only 43% maintained a loss of excess weight, nearly 60% required reoperation, and obesity-related comorbidities such as diabetes, hypertension, and sleep apnea persisted.

"The high failure rate of LAGB, at least in our hands, could be detrimental to its future continued widespread use as a restrictive weight loss operation," said Dr. Jacques Himpens and his associates at the European School of Laparoscopic Surgery, Saint Pierre University Hospital, Brussels.

In Europe there has been a marked shift in treatment, away from LAGB in favor of gastric bypass. "In contrast, in the United States, an opposite trend has been noted," even though some experts contend that LAGB "can result in a mediocre quality of life and a significant number of complications, and ... there is a tendency for patients to regain weight after some years," the investigators noted.

Dr. Himpens and his colleagues performed what they described as the first study of outcomes beyond the 10-year mark in patients who underwent LAGB using the perigastric technique. (The more recent "pars flaccida" technique and the current use of wider, softer bands than those used in the late 1990s may be improving outcomes, but that has not yet been proven, and many surgeons continue to use the perigastric technique, the researchers said.)

During the study period, 151 patients underwent LAGB using the perigastric technique at the hospital, but only 82 were available for a follow-up evaluation in 2009. "LAGB patients lost to follow-up are likely to experience very little weight loss. Our results must be viewed from this perspective," Dr. Himpens and his colleagues noted.

The 82 study subjects included 74 women and 8 men, with a mean body mass index of 42 kg/m2 (range 35-57), and a mean age of 50 years (range 28-73 years) at baseline.

Fifty patients (59%) developed complications, including 33 major complications such as pouch dilation, band erosion, and band infection. Incisional hernia, port-tubing disconnection, and port infection were considered minor complications.

It is noteworthy that most band erosions and pouch dilations developed "quite late," at a mean of 4 years after surgery, the authors wrote (Arch. Surg. 2011 March 21 [doi:10.1001/archsurg.2011.45]).

Approximately 60% of patients required at least one reoperation, because of complications or because they failed to lose weight or regained their weight.

Complete weight loss data were available for 70 patients. The mean percentage of excess weight loss was 43% in this group (range 24%-143%).

Overall, weight loss was modest. In the 70 patients, mean weight fell from 114 kg to 93 kg, and mean BMI decreased from 42 to 34. At follow-up, patient weight ranged from 37 to 165 kg, and BMI ranged from 35 to 57.

Hypertension, type 2 diabetes, and sleep apnea persisted or developed anew in 30%, 7%, and 8% of the participants, respectively.

Fourteen patients who switched to gastric bypass surgery after failure of LAGB showed better success with that procedure.

Despite these relatively poor outcomes with LAGB, 47 patients said they were "pleased" or "very pleased" with the procedure, and their scores on quality-of-life measures were the same as those in a nonsurgical population. This may explain why the public has not yet rejected "lap-band" surgery, even though many surgeons, at least in Europe, have done so, said Dr. Himpens and his associates.

Dr. Himpens is a consultant with Ethicon Endosurgery and Covidien, and his associates reported ties to Storz.

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