Clinical Inquiries

Should you evaluate for CAD in seniors with premature ventricular contractions?

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In 2006, the American College of Cardiology, American Heart Association, and European Society of Cardiology published their Guidelines for Management of Patients with Ventricular Arrhythmias and the Prevention of Sudden Cardiac Death.3

The TABLE summarizes characteristics of patients with PVCs who were at higher risk of underlying cardiac disease and death. All patients with PVCs should have a history and physical examination, electrocardiogram, and electrolyte studies. Higher-risk patients should be considered for further evaluation, including stress testing, echocardiography, and ambulatory electrocardiogram (SOR: C, opinion).

TABLE
Characteristics of patients with PVCs who are at higher risk of cardiac disease/death

PATIENT CHARACTERISTICSLOWER RISKHIGHER RISK
MorphologyUnifocal PVCs<10 PVCs per hourComplex multifocal PVCs Ventricular tachycardia Ventricular fibrillation >10 PVCs per hour
SymptomsAsymptomaticPalpitations Presyncope Syncope
Preexisting conditionsNoneKnown history of CAD Structural heart disease Valvular heart disease Cardiomyopathy
CAD, coronary artery disease, PVCs, premature ventricular contractions.
Source: American College of Cardiology et al.3

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