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Bilateral leg edema and difficulty swallowing

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In our patient’s initial workup, a CT (FIGURE 2), barium study (FIGURE 3), and endoscopy were all used to rule out an obstructive lesion.

FIGURE 2
Massively distended esophagus

A chest CT revealed a distended esophagus—at times 8 cm in diameter—from the thoracic inlet to the gastric inlet, strongly suggestive of achalasia. The patient’s trachea was displaced anteriorly, his posterior right lung was compressed, he had bilateral pleural effusions, and had generalized edema that was suggestive of anasarca.

FIGURE 3
The “bird’s beak” of achalasia

A barium swallow study showed diffuse enlargement of the esophagus with a narrowing “bird’s beak” near the esophagogastric junction, consistent with achalasia.

Treatment targets the constricted LES

The goal of treatment in achalasia is to help food move through the constricted LES. Pharmacologic therapy, used to decrease LES resting tone, has limited benefit and becomes less effective as the disease progresses. Calcium channel blockers, particularly nifedipine, and nitrates are the most commonly used agents.5

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