A practice recommendation in “Travelers diarrhea: Prevention, treatment, and post-trip evaluation" (J Fam Pract. 2013;62:356-361) incorrectly called for self-treatment with a fluoroquinolone (or azithromycin) and loperamide for diarrhea that is bloody or accompanied by fever. In fact, both the Centers for Disease Control and Prevention and the Infectious Diseases Society of America advise against the use of loperamide by travelers with fever or bloody diarrhea. The practice recommendation should have read: “Advise travelers to initiate self-treatment for travelers’ diarrhea with a fluoroquinolone (or azithromycin if in South or Southeast Asia) at the onset of diarrhea if it is bloody or accompanied by fever.”