Additionally, subdural empyema on neuroimaging increased from 1% to 16%, but was not associated with any particular serotype and was not associated with the cases of hemiparesis.
Overall, 52% of survivors had some sort of neurologic sequelae at the time of discharge, but there were no differences in terms of specific sequelae between the two groups.
The rates of morbidity and mortality for pneumococcal meningitis remain substantial and have not changed significantly since introduction of PCV13, Dr. Olarte said.
However, if the number of cephalosporin nonsusceptible pneumococci isolated from children with meningitis continues to decrease, modification of empiric antibiotic selection for suspected bacterial meningitis might be considered in the future, therefore ongoing surveillance is warranted, she said.
The studies were partially supported by Pfizer. The authors reported having no other disclosures.