Pediatrics
Q&A
Epinephrine is efficacious for outpatient treatment of bronchiolitis
BACKGROUND: Inhaled epinephrine is the most frequently prescribed bronchodilator for acute viral bronchiolitis. It stimulates alpha-receptors in...
Clinical Inquiries
What is the best treatment for Osgood-Schlatter disease?
EVIDENCE-BASED ANSWER: Osgood-Schlatter disease is a common cause of pain and tenderness at the tibial tuberosity in active adolescents. It is...
Q&A
Vaccinations containing thimerosal do not increase rates of autism
BACKGROUND: Thimerosal has historically been used as a preservative in many vaccines. Thimerosal contains ethyl mercury that has been postulated...
Clinical Inquiries
Are inhalers with spacers better than nebulizers for children with asthma?
EVIDENCE-BASED ANSWER: Metered-dose inhalers with a spacer (MDI/S) are as good as, or better than, nebulizers for children with asthma. This is...
Q&A
Sertraline effective for children and adolescents with major depression
BACKGROUND: Few treatment options are available for children and adolescents with major depressive disorder due to a lack of efficacy data,...
Q&A
Influenza vaccine does not prevent acute otitis media in young children
BACKGROUND: Influenza vaccines have been shown to prevent acute otitis media in children aged <2 years; reductions of 30% to 44% have been...
Q&A
Tubes for otitis media do not improve developmental outcomes
BACKGROUND: Ear infections are common occurrences in pediatric patients. Children who suffer from frequent bouts of these infections may have...
Clinical Inquiries
Is screening urinalysis in children worthwhile?
EVIDENCE-BASED ANSWER: Screening urinalysis in asymptomatic children has not been shown to be beneficial (strength of recommendation: B; based on...
Clinical Inquiries
Should jaundiced infants be breastfed?
EVIDENCE-BASED ANSWER: No studies have demonstrated that cessation of breastfeeding in jaundiced infants improves clinical outcomes, although this...
Clinical Inquiries
Which infants need lumbar puncture for suspected sepsis?
EVIDENCE-BASED ANSWER: Evidence from prospective and retrospective clinical trials suggests that for infants <2 months old, only those at high...
Clinical Inquiries
What medication best prevents migraine in children?
EVIDENCE-BASED ANSWER: Propranolol, valproic acid, and amitriptyline are effective prophylaxis for migraine in children to varying degrees, are...