Anemia
Feature
Novel research aims to improve ED care in sickle cell disease
Researchers are testing the best acute pain management strategies to respond to a vasoocclusive crisis.
Feature
Ongoing research aims to improve transplant outcomes in sickle cell
Over the past 2 years, the majority of novel transplant techniques have been primarily aimed at improving conditioning regimens and lowering rates...
News
CDC awards $1.2 million to learn about people with sickle cell disease
The funding will go toward a 1-year project to build infrastructure in nine states to gather unique data and conduct in-depth analysis among...
Conference Coverage
Novel gene therapies show promise for sickle cell cure
Gene-addition and gene-editing therapies are currently in clinical development.
From the Journals
Can we eradicate malaria by 2050?
A Lancet Commission report details a series of modeled projections that could point the way.
Feature
U.S. and African programs aim to improve understanding, treatment of sickle cell disease
The various programs include efforts to build a registry for patients with sickle cell disease and ways to optimize the use of hydroxyurea in...
From the Journals
Mitapivat elicits positive response in pyruvate kinase deficiency
The safety data from this phase 2 study suggest that mitapivat could be administered long term for patients with pyruvate kinase deficiency.
From the Journals
Quercetin may reduce iron overload in beta-thalassemia major
Quercetin is part of the flavone family that exists mainly in apples, berries, onions, tea, and red wine.
From the Journals
Two iron chelators better than one for thalassemia major
In a single-center study, deferasirox plus deferoxamine significantly decreased cardiac iron and serum ferritin, but deferasirox alone did not.
From the Journals
Timing, volume of transfusion may not matter in children with severe anemia
The TRACT trial showed no significant differences in 28-day mortality or other clinical outcomes by transfusion timing or volume.
From the Journals
Hemoglobin levels are associated with long-term dementia risk
Both low and high levels of hemoglobin are linked with an increased risk of dementia, according to a population-based study of adults in the...