Conference ReCAP

Top Abstracts in Locally Advanced NSCLC From ASCO 2021


 

Dr Thomas Stinchcombe, from Duke Cancer Center in Durham, North Carolina, highlights key abstracts in locally advanced non–small cell lung cancer (NSCLC) presented at the 2021 annual meeting of the American Society of Clinical Oncology.

First, he reviews the IMpower010 trial, which compares atezolizumab vs best supportive care in patients with surgically resected NSCLC who had received adjuvant chemotherapy.

He then discusses surgical outcomes from the CheckMate 816 trial in patients with resectable NSCLC who had been treated with nivolumab plus platinum-doublet chemotherapy vs chemotherapy alone.

Finally, Dr Stinchcombe discusses the IMPACT trial, which looked at adjuvant gefitinib vs cisplatin/vinorelbine in completely resected NSCLC patients with EGFR mutations.
--

Thomas E. Stinchcombe, MD, Medical Oncology, Duke Cancer Center, Durham, North Carolina.

Thomas E. Stinchcombe, MD, has disclosed the following relevant financial relationships:
Received research funding from: Genentech/Roche; Blueprint Medicines; AstraZeneca
Received income in an amount equal to or greater than $250 from: Takeda; AstraZeneca; Genentech/Roche; Foundation Medicine; Pfizer; EMD Serono; Novartis; Daiichi Sankyo; Eli Lilly and Company; Medtronic.

Recommended Reading

Immunotherapy takes first major step into earlier NSCLC
MDedge Hematology and Oncology
NSCLC: Immune-related AEs during checkpoint inhibitor therapy may predict outcomes
MDedge Hematology and Oncology
Community practice lung cancer patients insufficiently tested for treatment-related biomarkers
MDedge Hematology and Oncology
KRAS inhibitor improved survival in phase 2 lung cancer trial
MDedge Hematology and Oncology
Vinorelbine survival benefit in mesothelioma overshadowed by advances in immuno-oncology
MDedge Hematology and Oncology
Urine metabolites could predict end of life in lung cancer
MDedge Hematology and Oncology
Nasal swab test helps identify malignant lung nodules
MDedge Hematology and Oncology
Surgical outcomes favor addition of nivolumab to neoadjuvant chemo in resectable lung cancers
MDedge Hematology and Oncology
HER3-targeted treatment demonstrates efficacy and safety in phase 1 lung cancer study
MDedge Hematology and Oncology
Key Presentations on Advanced Non–Small Cell Lung Cancer From ASCO 2021
MDedge Hematology and Oncology