Bleeding Disorders
From the Journals
Occult HCV infection is correlated to unfavorable genotypes in hemophilia patients
Unfavorable interferon gentoypes were correlated to occult HCV infection in paitents with hemophilia.
From the Journals
Turoctocog alfa prevented, treated bleeds in previously untreated pediatric patients with severe hemophilia A
In guardian 4, the first trial in its series to evaluate previously untreated patients, recombinant factor VIII was well tolerated, and...
Conference Coverage
Age, sex, and other factors linked to risk of intracranial hemorrhage in ITP
ORLANDO – Being older, male, and not having private insurance were some of the risk factors for intracranial hemorrhage among patients with immune...
Conference Coverage
Phase 2 studies show potential of FcRn blockade in primary ITP
ORLANDO – The results support continued investigation in phase 3 trial for rozanolixizumab and efgartigimod, according to investigators.
Conference Coverage
Think twice: Choosing Wisely recommendations on testing to avoid in pediatric hematology
ORLANDO – The list, which was released by ASH and the American Society of Pediatric Hematology/Oncology, includes five unnecessary tests or...
Conference Coverage
Best practice alerts really can work
SAN ANTONIO – A majority of alerts triggered by red blood cell orders were overridden, but for sound clinical reasons, investigators found.
Conference Coverage
Fresh RBCs offer no benefit over older cells in pediatric ICU
SAN ANTONIO – Exposure to fresh red cells may be associated with immune suppression because viable white cells may also be present in the product...
From the Journals
Emicizumab effective in children with hemophilia A and inhibitors
Emicizumab stands to become the “next-generation standard of care” for these pediatric patients, report says.
Conference Coverage
Fibrinogen concentrate effective, safe for postop bleeding
SAN ANTONIO – Favored more in Europe than North America, fibrinogen concentrate was noninferior to cryoprecipitate for control of bleeding after...
From the Journals
Updated international consensus recommendations on management of acute upper GI bleeding
Updated guidelines on management of nonvariceal acute upper GI bleeding address questions on endoscopic techniques and pharmacologic management....
Guidelines
ISTH releases draft guideline for TTP diagnosis, treatment
The guideline provides recommendations for adult patients with either immune or hereditary TTP, from acute events through remission, including...