Bleeding Disorders
News
Eltrombopag yields 40% response rate in pediatric immune thrombocytopenia
Key clinical point: Eltrombopag markedly outperformed placebo and had no new safety signals in children and adolescents with chronic immune...
News
Drug-induced iron deficiency decreased congenital erythropoietic porphyria symptoms
After 2 months of deferasirox therapy, the patient’s serum ferritin level dropped to 16 ng/mL
News
Dicloxacillin may cut INR levels in warfarin users
The antibiotic dicloxacillin appears to markedly decrease INR levels in patients taking warfarin.
News
World Federation of Hemophilia Seeks Proposals
Conference Coverage
Surgical bleeding risk ‘remarkable’ with platelet disorders
Key clinical point: Inherited platelet function disorders are associated with a significant surgical bleeding risk. Major finding: The frequency...
News
Gene therapy trial underway in hemophilia B
Key clinical point: BAX 335, a new gene therapy candidate, is now in a phase I-II trial in hemophilia B patients. Major finding: In the...
Guidelines
Study establishes protocol for perioperative dabigatran discontinuation
Key clinical point: The risk of stroke and major bleeding can be reduced to low levels using a formalized strategy for stopping and then...
Conference Coverage
Idarucizumab reverses dabigatran’s anticoagulant effects
Key clinical point: The investigational monoclonal antibody idarucizumab reversed the anticoagulant effects of dabigatran. Major finding:...
News
Promacta approved for pediatric treatment of chronic ITP
Conference Coverage
DDW: VIDEO: What we don’t know in the management of liver disease and coagulopathy
WASHINGTON – Your patient has cirrhosis, platelets 60,000 mm3, an INR of 2.0, serum creatinine of 1.2 mg/dL, and requires an endoscopic retrograde...