GI Oncology
News
New immunomodulator shows promise in pancreatic cancer
Key clinical point: IMM-101 appears safe and efficacious when added to gemcitabine as first-line therapy. Major finding: Median overall survival...
News
Choose colonoscopy over sigmoidoscopy for screening of proximal advanced serrated lesions
Key clinical point: Screening colonoscopy is more effective than sigmoidoscopy for detection of proximal advanced serrated lesions and,...
Conference Coverage
Survival seen in mCRC trials has limited generalizability to real world
Key clinical point: Survival of patients with metastatic colorectal cancer in the real world falls short of that in clinical trials. Major finding...
Conference Coverage
AFP may help guide ramucirumab therapy in advanced HCC
Key clinical point: Pretreatment AFP levels may be a biomarker for ramucirumab benefit. Major finding: Patients with AFP levels of 400 ng/mL or...
News
Statins found to have a survival benefit in colorectal cancer
Key clinical point: Patients with colorectal cancer who take statins are less likely to die. Major finding: Relative to nonusers, statin users had...
News
Preoperative hepatic, regional arterial chemo nets better outcomes in early CRC
Key clinical point: Preoperative arterial chemotherapy improves outcomes, but mainly for stage III patients. Major finding: Five-year disease-free...
Conference Coverage
New kinase inhibitor is highly active in MET-amplified gastric cancer
Key clinical point: AMG 337 promoted tumor regression in patients with MET-amplified esophagogastric cancers. Major finding: The response rate was...
News
Vitamin D appears protective in patients with metastatic colorectal cancer
Key clinical point: Patients with higher 25-hydroxyvitamin D levels had better progression-free and overall survival. Major finding: Median...
Conference Coverage
Skipping surgery is an option for some patients with rectal cancer
Key clinical point: Patients with rectal cancer who have a clinical complete response to neoadjuvant therapy can safely skip surgery. Major...
News
Outcomes of stage III colon cancer appear better for aspirin, COX-2 inhibitor users
Key clinical point: Among patients with stage III colon cancer, users of aspirin or COX-2 inhibitors appear less likely to have a recurrence and...
News
Microbiota organization influences colorectal cancers
Key clinical point: The organization of the mucosa-associated microbial community is an important factor in CRC pathogenesis, particularly in the...