Metastatic Breast Cancer
Latest News
Tumor-bed radiotherapy boost reduces DCIS recurrence risk
Regardless of the whole breast irradiation fractionation schedule, a 16 Gy tumor-bed boost halved the risk of DCIS recurrence at 5 years.
Feature
Getting cancer research on track again may require a ‘behemoth’ effort
Cancer Moonshot aims to cut cancer-related deaths in half, but funding and pandemic challenges may hinder progress.
News
FDA approves trastuzumab-deruxtecan for HER2-low breast cancer
Sixty percent of patients previously classified as having HER2-negative subtype are now considered HER2 low.
From the Journals
Node-negative triple-negative breast cancer prognosis lies within stromal lymphocytes
Every 10% increase in stromal tumor-infiltrating lymphocytes was associated with a 19% reduction in the risk of death.
Feature
Life and death decisions: What keeps oncologists up at night
“It’s part of the discomfort you live with as a patient and oncologist, and when I leave the clinic, that’s one thing that follows me home.”
From the Journals
Study confirms BRCA1 and BRCA2 linked to seven cancers
Some associations are stronger than others with biliary tract, esophageal, and gastric cancers rising to the top.
Feature
Sociogenomics may explain race disparities in breast cancer mortality
Research aimed at understanding and mitigating the effects of persistent marginalization urgently needed.
From the Journals
Quality of life benefit exaggerated in some cancer studies
From the Journals
‘Unexpected’: Breast cancer spreads most during sleep
The findings carry potential implications for the timing of biopsy and treatment of metastasis-prone cancers, the authors say.
From the Journals
Good chemo vs. bad chemo: When too much is a bad thing
Study questions the use of inpatient chemotherapy pointing to negative outcomes and high mortality among some patients.
The Practicing Oncologist
My picks for best of ASCO 2022
First-line treatment for colorectal cancer, possible new standard of care for breast cancer, and more.