Myelodysplastic Syndrome

Monosomal karyotype, high prognostic risk score predicted transplantation failure

Publish date: March 31, 2014

Major finding: Patients with a monosomal karyotype had a 49% relapse rate and a 10% 5-year overall survival rate, and those considered high or...

Publish date: March 31, 2014

Major finding: The addition of cell-cycle inhibitor entinostat to a 10-day schedule of treatment with azacitidine led to a lower overall...

Publish date: December 27, 2013

Major finding: An increase in QTcF from baseline of more than 60 msec was seen in 19% of patients on quizartinib 60 mg and in 3% of those on 30 mg...

Publish date: October 4, 2013

The drug, CPI-613, targets metabolic changes that are thought to occur in many cancer cells. It has demonstrated activity and tolerability in a...

Publish date: July 2, 2012

In a multicenter trial, deferasirox reduced serum ferritin and labile plasma iron (LPI) in transfusion-dependent patients with myelodysplastic...

Publish date: March 14, 2012

Major Finding: In one study 97.3% of samples from patients with AML had mutations in 18 genes.