Neuro-oncology
Guidelines
CNS lymphoma guidelines stress patient fitness, not age, in choosing treatment
Patients should be diagnosed fast, treated as aggressively as organ health permits, and in clinical trials if possible.
From the Journals
Bacteremic sepsis in ALL linked to later cognitive issues
Patients who survive acute lymphoblastic leukemia still may face cognitive impairment later in life because of sepsis during treatment.
From the Journals
Immunotherapies extend survival for melanoma patients with brain metastases
Patients with melanoma brain metastases receiving first-line checkpoint blockade immunotherapy had a 91% increase in 4-year survival.
From the Journals
Recombinant poliovirus appears safe, active as recurrent glioblastoma treatment
The survival data in a phase 1 study of 61 patients showed a plateau, with a 36-month survival rate of 21%, compared with 4% for a historical...
News
FDA: Gadolinium retention prompts new GBCA class warning, safety measures
Gadolinium-based contrast agents used for MRI will now carry a warning regarding potential retention in the bodies and brains of treated patients...
News
FDA: Gadolinium retention prompts new GBCA class warning, safety measures
Gadolinium-based contrast agents used for MRI will now carry a warning regarding potential retention in the bodies and brains of treated patients...
News
FDA approves biosimilar to bevacizumab
Bevacizumab-awwb is approved for the treatment of adults with certain colorectal, lung, brain, kidney, and cervical cancers.
From the Journals
Pembrolizumab, nivolumab linked to 3% rate of neurologic events
Ten of 347 patients (2.9%) receiving nivolumab or pembrolizumab developed subacute neurologic immune-related adverse events, typically...
Feature
Glioblastoma: Prognosis is poor, but new therapies are emerging
Intensive, up-front treatment may help elderly patients with glioblastoma the most.
Conference Coverage
Atezolizumab improves OS in NSCLC with brain metastases
GENEVA – Immune checkpoint inhibitors may improve survival in patients with non–small cell lung cancer (NSCLC) and brain metastases compared with...
Conference Coverage
Neuropathic pain puts cancer survivors out of work
Chronic neuropathic pain is a barrier to employment for many cancer survivors.