Transplantation
News
Prophylaxis reduces bacteremia in some kids
In a phase 3 study, levofloxacin prophylaxis significantly reduced bacteremia in children with acute leukemias who received intensive chemotherapy...
News
Team identifies potential immunotherapy target for AML
New research could aid the development of immunotherapies tailored to patients with acute myeloid leukemia (AML) who are undergoing stem cell...
News
New guidelines on antimicrobial prophylaxis
Experts have published updated guidelines on antimicrobial prophylaxis for adults with cancer-related immunosuppression. The guidelines include...
News
Mechanism of cGVHD response to ECP still unclear
A prospective study did not reveal the mechanism driving response to extracorporeal photopheresis (ECP) in patients with chronic graft-versus-host...
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OMS721 receives orphan designation for use in HSCT
The European Commission has granted orphan designation to OMS721 for use in the setting of hematopoietic stem cell transplant (HSCT). OMS721 is a...
News
Auto-HSCT linked to higher AML, MDS risk
Patients undergoing autologous hematopoietic stem cell transplant (auto-HSCT) for lymphoma or myeloma have an increased risk of acute myeloid...
News
FDA grants fast track designation to dilanubicel
The US Food and Drug Administration (FDA) has granted fast track designation to dilanubicel (NLA101) for use in patients with high-risk...
News
A new way to expand HSCs for UCB transplant
Researchers say they have discovered a new approach to expand hematopoietic stem cells (HSCs) from umbilical cord blood (UCB). The team...
News
FDA advises against azithromycin use in allo-HSCT recipients
The US Food and Drug Administration (FDA) is warning against long-term use of azithromycin (Zithromax, Zmax) in patients who undergo allogeneic...
News
Kids may have higher risk of death long after allo-HSCT
Children may have an increased risk of premature death decades after allogeneic hematopoietic stem cell transplant (allo-HSCT), according to a...
News
Orphan designation recommended for OMS721
The European Medicines Agency’s (EMA’s) Committee for Orphan Medicinal Products (COMP) has issued a positive opinion recommending orphan drug...