- inconsistent or no condom use.
- diagnosis of sexually transmitted infections.
- exchange of sex for commodities (such as money, food, shelter, or drugs).
- use of illicit drugs or alcohol dependence.
- incarceration.
- partner(s) of unknown HIV-1 status with any of the factors listed above.
Dosage and administration
2.1 Testing prior to initiation of Truvada for treatment of HIV-1 infection or for HIV-1 PrEP
Prior to or when initiating Truvada, test patients for hepatitis B virus infection [see Warnings and Precautions (5.1)].
Prior to initiation and during use of Truvada, on a clinically appropriate schedule, assess serum creatinine, estimated creatinine clearance, urine glucose and urine protein in all patients. In patients with chronic kidney disease, also assess serum phosphorus