From the Journals

Single screening for Lynch syndrome beats sequential tests in CRC


 

FROM JAMA ONCOLOGY


Eesults from tumor sequencing are available in a median of 2 weeks, which may be longer than some other tests, but “it requires less time overall by eliminating multiple follow-up tests in a subset of cases,” the study authors wrote.

“While this new test is currently more expensive than traditional step-wise testing, it will eliminate many other tests for a subset of patients so that it may be more cost-effective overall. If it is not now, it will certainly be in the future as the costs of tumor sequencing continue to decline,” Ms. Pearlman said. “However, formal cost-analysis studies will be necessary to determine if this is a cost-effective approach.”

The study was funded by a grant from Pelotonia, an annual cycling event that supports cancer research, and the National Cancer Institute. Myriad Genetics donated the sequence testing used for some patients.

SOURCE: Hampel H et al. JAMA Oncol. 2018 Mar 29. doi: 10.1001/jamaoncol.2018.0104.

Pages

Recommended Reading

Opioids linked to mortality in IBD
MDedge Internal Medicine
AGA Clinical Practice Update: Incorporating psychological care in the management of chronic digestive diseases
MDedge Internal Medicine
VIDEO: Organ-sparing resection techniques should be way of the future
MDedge Internal Medicine
VIDEO: It is an exciting time in obesity treatment
MDedge Internal Medicine
Step-up diet: Less-intensive way to ID eosinophilic esophagitis food triggers?
MDedge Internal Medicine
Medical treatment of perianal fistulae often warranted, despite limited evidence
MDedge Internal Medicine
MDedge Daily News: Is kratom the answer to the opioid crisis?
MDedge Internal Medicine
Survival worse with alcohol-related HCC, compared with other types
MDedge Internal Medicine
Sessile serrated colon polyps may be detectable noninvasively
MDedge Internal Medicine
MDedge Daily News: Why low-calorie sucralose may fuel weight gain
MDedge Internal Medicine