Breast Cancer
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Genentech Appeals to FDAs Regulatory Flexibility on Avastin
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Radioactive Seeds Guide Surgeons to Nonpalpable Breast Lesions
Major Finding: Radioactive seed localization resulted in initial negative margins in 85% of cases and an overall re-excision rate of 2%. Data...
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Sequencing Reveals MAP3K1 Mutation in Luminal-Type Breast Cancer
Major Finding: A three-gene cluster of mutated MAP3K1, mutated PIK3CA, and wild-type TP53 was shown to be significantly associated with "luminal A...
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NCCN Breast Guidelines Stand by Bevacizumab
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Bone Micrometastases Show No Survival Impact in Early Breast Cancer
Major Finding: Overall survival was 92.7% in patients without BMM and 92.5% in those with BMM.Data Source: A prospective Swiss Multicenter Study...
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Clinical Trial Participation Tied to Improved Breast Cancer Outcomes
Major Finding: Among 1,220 women, 56% of patients treated by a surgical oncologist participated in a clinical trial, compared with 7% of general...
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Techniques Compared for Breast Tumor Detection
Major Finding: Positive margin rates were 10.5% for radio-guided seed localization and 11.9% for wire-guided localization.Data Source: Prospective...
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Eribulin Extends Survival of Women With Heavily Pretreated Breast Cancer
Major Finding: Median overall survival rate reached 13.1 months in women treated with eribulin, compared with 10.6 months in the control group (P...
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Trastuzumab Benefit Persists at 4 Years in HER2-Positive Breast Cancer
Major Finding: Disease-free survival at a median follow-up of 48.4 months in 1,703 women initially randomized to receive 1 year of treatment with...