Rare Diseases
Conference Coverage
Upadacitinib Proves Successful in First JAK Inhibitor Trial for Giant Cell Arteritis
Results from the SELECT-GCA study showed that upadacitinib (Rinvoq) induced significant and sustained remission in people with new-onset or...
News from the FDA/CDC
FDA Grants New Pediatric Arthritis Indications for Upadacitinib
The JAK inhibitor’s safety profile for patients as young as 2 years was similar to the known safety profile in adults.
Latest News
Inebilizumab ‘MITIGATES’ Flare Risk in IgG4-Related Disease
Inebilizumab-cdon reduced the risk for flares by 87% in patients with IgG4-RD, the MITIGATE study showed.
Commentary
Don’t Miss the Dx: A 24-Year-Old Man With Sudden-Onset Hematuria, Proteinuria, Edema, and Hypertension
The patient was diagnosed with complement 3 glomerulonephritis, which may have a genetic component.
Latest News
FDA Requests More Information for RDEB Rx Under Review
Pz-cel, which comprises autologous, COL7A1 gene–corrected epidermal sheets, is being evaluated for its ability to enable normal type VII...
Guidelines
New British Behçet’s Disease Guidelines Emphasize Multidisciplinary Management
The British Society for Rheumatology and the British Association of Dermatologists developed guidelines for the management of people living with...
Latest News
New Insight Into ‘Demon’ Facial Visual Perception Disorder
Researchers create images that depict PMO, a condition causing visual distortion of faces.
Latest News
Tooth Enamel Disorder Is a Feature of Kindler EB
All 11 patients with information on enamel structure in their records had pitted enamel anomalies, with variable severity.
Feature
Autoimmunity’s Female Bias and the Mysteries of Xist
Researchers are homing in on a long non-coding RNA, essential to X chromosome inactivation, as the culprit in sex-biased autoimmune diseases like...
News from the FDA/CDC
Second FDA-Approved Tocilizumab Biosimilar Has Intravenous, Subcutaneous Formulations
It’s unclear when the new tocilizumab products will be commercially available.
Latest News
Oral Transmission of Chagas Disease Has Severe Effects
"A myth I would like to dispel is that Chagas disease is not being transmitted in the United States."