Conference Coverage

European cardiologists seek involvement in acute stroke

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Multispecialty approach is key to U.S. rollout

The convergence of technological advancements for intracranial mechanical thrombectomy (stent retrievers) and the use of noninvasive imaging (CTA/MRA) to improve patient selection for revascularization have revolutionized the treatment of acute stroke as demonstrated by the recent publication of five randomized clinical trials supporting revascularization for acute ischemic stroke. Similar to our national goal for minimizing door to balloon time (DTB) for acute heart attacks, there will now be a similar effort directed at expediting stroke treatment.

Dr. Christopher J. White

However, we have not solved the manpower issue of offering this specialized therapy in the local hospitals where the stroke patients are. Unfortunately, the demand for endovascular stroke treatment has outstripped the ability of traditional radiology specialists to provide this care, in many hospitals. The good news is that many other specialists, including interventional neurologists, vascular surgeons, neurosurgeons, and interventional cardiologists have endovascular skills readily adaptable to treating patients with acute stroke.

At Ochsner Medical Center in New Orleans, we have demonstrated the feasibility of interventional cardiologists working 24-7–365 with neurologists as a team, to perform endovascular revascularization for acute stroke patients. Reassuringly, we found no difference in outcomes among those acute stroke patients treated by radiology specialists and those treated by the interventional cardiology team (Catheter. Cardiovasc. Interven. 2015;85:1043-50). Because there is an uneven distribution of radiology specialists in our communities where patients with strokes need time-sensitive treatment, we need to develop teams composed of a variety of physician specialties, including interventional cardiologists, who can deliver rapid and safe intracranial mechanical thrombectomy to selected patients with acute stroke in their local communities.

Dr. Christopher J. White is medical director of the John Ochsner Heart & Vascular Institute in New Orleans. He is an adviser to and consultant for Neovasc, and consults for Surmodics.


 

EXPERT ANALYSIS FROM EUROPCR 2015

References

“We must offer this intervention to as many patients as possible,” stressed Dr. Bonafe, professor of neuroradiology at the University of Toulouse and president of the French Society of Neuroradiology. “In most places it’s not offered at all, or only part-time by a few experts. So I think cardiologists should join the force, and everybody who is expert in procedural interventions should be trained for this in order to cover the need for the whole population.”

Dr. Kenneth K. Snyder observed that as recently as 2013, the rumor was that endovascular stroke therapy was dead. Three randomized trials published in the New England Journal of Medicine – IMS III, SYNTHESIS, and MR RESCUE – had found no difference between endovascular therapy and standard medical therapy.

But only 5% of the participants in those trials were treated with modern clot retrievers, which are much more effective than earlier-generation devices. And the negative trials didn’t specifically target large-vessel occlusions, which is where device therapy clearly works best.

“Stroke is now a surgical disease. Many of us have believed this from the get go. In centers with advanced systems of stroke care, endovascular therapy can significantly improve functional outcomes without compromising safety as compared to standard therapy,” said Dr. Snyder, a neurosurgeon specializing in endovascular therapy at the State University of New York at Buffalo.

In the United States, he noted, stroke is the fourth leading cause of mortality, the No. 1 cause of long-term disability, the most common discharge diagnosis to nursing homes, and carries a cost of $70 billion annually. Worldwide, stroke is the second leading cause of mortality. And stroke rates will continue to grow.

He said conflict between specialties regarding provision of state-of-the-art acute stroke therapy is not inevitable, as can be seen at the acute stroke unit at SUNY Buffalo.

“Our center is collaborative and multidisciplinary. We have 20 interventional suites. We all work next to each other and with each other – the cardiologists next to the interventional radiologists next to the neurosurgeons. It forces a great deal of collaboration. And we have a track record of training cardiologists both in observerships and also in formal training programs,” Dr. Snyder said.

The speakers declared having no financial conflicts.

bjancin@frontlinemedcom.com

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