From the Journals

Rosacea patients host the most mites


 

FROM JAAD

Infestation with Demodex mites was significantly more common in patients with rosacea compared with healthy controls, based on data from a meta-analysis of 1,513 adults with rosacea. The findings were published in the September issue of the Journal of the American Academy of Dermatology.

The cause of rosacea remains unclear and differs within subgroups, but previous studies have suggested an association between rosacea and the presence of Demodex mites, wrote Yin-Shuo Chang, MD, and Yu-Chen Huang, MD, both of Taipei Medical University, Taiwan (J Am Acad Dermatol. 2017; 77[3]:441-7).

Rosacea: Inflammatory papules and pustules observed over the nose in an individual with rosacea. M. Sand, et al/Head & face medicine/ISSN 1746-160X/CC BY 2.0

Rosacea: Inflammatory papules and pustules observed over the nose in an individual with rosacea.

The researchers reviewed data from 23 case-control studies including 1,513 adults with rosacea. Overall, rosacea patients were 9 times more likely to experience Demodex mite infestations than healthy controls (odds ratio, 9.039) and the infestations were significantly denser in rosacea patients compared with controls. The density of the mites was significantly higher than controls for patients with either erythematotelangiectatic rosacea (standardized mean difference 2.686 or papulopustular rosacea (standardized mean difference, 2.804).

Courtesy RegionalDerm.com

The Demodex mite

The findings were limited by several factors such as the variables in design among the studies in the analysis, and the inability of a meta-analysis to show a causal relationship, the researchers noted. However, the association between rosacea and the high prevalence of Dermodex mites “suggests that mites may play a pathogenic role in this disease,” they said.

The researchers had no financial conflicts to disclose.

Find the full study online here: http://www.jaad.org/article/S0190-9622(17)30429-2/fulltext.

Recommended Reading

Ocular rosacea remains a stubborn foe
MDedge Internal Medicine
‘Anxiety sensitivity’ tied to psychodermatologic disorders
MDedge Internal Medicine
A sweet new solution for rosacea
MDedge Internal Medicine
FDA approves topical oxymetazoline for rosacea
MDedge Internal Medicine
VIDEO: Oxymetazoline approval expands options for rosacea
MDedge Internal Medicine
Rosacea research reveals advances, promising therapies
MDedge Internal Medicine
Some data support botulinum toxin for psoriasis and rosacea
MDedge Internal Medicine
Dermatologist calls for paradigm shift on treating ocular rosacea
MDedge Internal Medicine
Clues to rosacea in patients of skin of color
MDedge Internal Medicine
Rosacea: Expert recommends treating erythema, papules/pustules simultaneously
MDedge Internal Medicine